Review

Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals

Volume: 6 Number: 3 September 29, 2022
EN

Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals

Abstract

Learning and memory regulate the necessary mental processes such as evaluating stimuli from the environment and developing appropriate behaviors. People consciously or unconsciously resort to memory functions in every process they perform. Experiences that emerge through interaction with the environment lead to changes and shaping of behaviors. Thus, learning of different behavioral phenomena takes place. Memory ensures that this learned behavioral information is stored and used when necessary. The central nervous system is capable of storing and processing information in mammals. Research on learning and memory in humans is limited due to ethical rules. Therefore, different experimental tests evaluating learning and memory states in rodents have been designed to find effective treatment strategies. The aim of this review is to provide information about the most commonly used learning and memory tests in experimental animals.

Keywords

References

  1. 1. Pittenger C, Kandel ER. In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358(1432):757-63.
  2. 2. Hall JE, Guyton AC. Guyton and Hall textbook of medical physiology. 13 th edition. Philadelphia, Saunders Elsevier, 2016.
  3. 3. Gasparini L, Racchi M, Binetti G, Trabucchi M, Solerte SB, Alkon D, et al.Peripheralmarkers in testing pathophysiological hypotheses and diagnosingAlzheimer's disease. FASEB J. 1998 Jan;12(1):17-34.
  4. 4. Waxman A, Chugani H, Seibyl J. Medical imaging in neurological disorders.J Am Pharm Assoc (Wash). 2002 Sep-Oct;42(5 Suppl 1):S48-9.
  5. 5. Phelps EA, LeDoux JE. Contributions of the amygdala to emotion processing: from animal models to human behavior. Neuron. 2005;48(2):175-187. doi:10.1016/j.neuron.2005.09.025 6. Morgane PJ, Galler JR, Mokler DJ. A review of systems and networks of the limbic forebrain/limbic midbrain. Prog Neurobiol. 2005 Feb;75(2):143-60.
  6. 7. Mineur YS, Obayemi A, Wigestrand MB, Fote GM, Calarco AC, Li AM, et al. Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior. Proc Natl Acad Sci U S A. 2013;110(9):3573-3578. doi:10.1073/pnas.1219731110
  7. 8. Morris R. Developments of a water-maze procedure for studying spatial-learning in the rat. J. Neurosci. Methods. (1984) 11, 47–60.
  8. 9. Shultz SR, McDonald SJ, Corrigan F, Semple BD, Salberg S, Zamani A, et al. Clinical Relevance of Behavior Testing in Animal Models of Traumatic Brain Injury. J Neurotrauma. 2020;37(22):2381-2400. doi:10.1089/neu.2018.6149

Details

Primary Language

English

Subjects

Health Care Administration

Journal Section

Review

Publication Date

September 29, 2022

Submission Date

November 1, 2021

Acceptance Date

April 17, 2022

Published in Issue

Year 2022 Volume: 6 Number: 3

APA
Dalkiran, B., Açıkgöz, B., & Dayı, A. (2022). Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals. Journal of Basic and Clinical Health Sciences, 6(3), 938-945. https://doi.org/10.30621/jbachs.1017172
AMA
1.Dalkiran B, Açıkgöz B, Dayı A. Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals. JBACHS. 2022;6(3):938-945. doi:10.30621/jbachs.1017172
Chicago
Dalkiran, Bahar, Burcu Açıkgöz, and Ayfer Dayı. 2022. “Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals”. Journal of Basic and Clinical Health Sciences 6 (3): 938-45. https://doi.org/10.30621/jbachs.1017172.
EndNote
Dalkiran B, Açıkgöz B, Dayı A (September 1, 2022) Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals. Journal of Basic and Clinical Health Sciences 6 3 938–945.
IEEE
[1]B. Dalkiran, B. Açıkgöz, and A. Dayı, “Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals”, JBACHS, vol. 6, no. 3, pp. 938–945, Sept. 2022, doi: 10.30621/jbachs.1017172.
ISNAD
Dalkiran, Bahar - Açıkgöz, Burcu - Dayı, Ayfer. “Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals”. Journal of Basic and Clinical Health Sciences 6/3 (September 1, 2022): 938-945. https://doi.org/10.30621/jbachs.1017172.
JAMA
1.Dalkiran B, Açıkgöz B, Dayı A. Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals. JBACHS. 2022;6:938–945.
MLA
Dalkiran, Bahar, et al. “Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals”. Journal of Basic and Clinical Health Sciences, vol. 6, no. 3, Sept. 2022, pp. 938-45, doi:10.30621/jbachs.1017172.
Vancouver
1.Bahar Dalkiran, Burcu Açıkgöz, Ayfer Dayı. Behavioral Tests Used in the Evaluation of Learning and Memory in Experimental Animals. JBACHS. 2022 Sep. 1;6(3):938-45. doi:10.30621/jbachs.1017172

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