Analysis of Cancers in A University Hospital Employees between 2006 and 2022

Abstract

Objective: Healthcare workers are exposed to a variety of hazardous chemicals and agents that may have long-term effects on their health. One of the health problems caused by these chemicals and agents is cancer. The aim of this descriptive study is to evaluate the cancers seen in those working in a university hospital between 01.01.2006 and 30.06.2022. Material – Methods: All healthcare professionals diagnosed with cancer between 01.01.2006-30.06.2022 were included in this descriptive study. The age, sex, occupation, working unit, and cancer type of the patients were evaluated. Data were analyzed with the statistical program SPSS-22 (SPSS Inc., Chicago, IL, USA). Data were presented using descriptive statistics (means and standard deviations for continuous variables; numbers and percentages for categorical variables). Results: Between 01.01.2006 and 30.06.2022, 186 people working at Sivas Cumhuriyet University were diagnosed with cancer. Forty-seven point eight percent (n = 89) of them are male; the mean age of those diagnosed with cancer is 46.0 ± 8.9 (min 22, max 62). The most common cancers are thyroid (21.5%), breast (16.7%), head and neck (9.7%), hematopoietic system (9.1%), and gastric-colon (8.6%) cancers. When evaluated according to occupational groups, 22.6% of them are office workers, 19.9% are academicians, 15.6% are workers, 14.0% are nurses, 10.2% are health technicians, and 8.2% are research assistants. Conclusion: In this institution, which has 2721 personnel, approximately 16 employees are diagnosed with cancer each year. Detailed records of patients diagnosed with cancer, especially healthcare professionals, should be kept. More studies are needed in detail on behaviors related to occupational exposures and cancer risk. It may be beneficial reducing the burden of work-related cancers also for the well-being of healthcare workers.

Keywords

• healthcare professionals
• cancer
• epidemiology

References

1. Takala J. Eliminating occupational cancer. Ind Health. 2015;53(4):307-9. doi: 10.2486/indhealth.53-307. PMID: 26377441; PMCID: PMC4551060.
2. Rai R, Fritschi L, Carey RN, Lewkowski K, Glass DC, Dorji N, El-Zaemey S. The estimated prevalence of exposure to carcinogens, asthmagens, and ototoxic agents among healthcare workers in Australia. Am J Ind Med. 2020 Jul;63(7):624-633. doi: 10.1002/ajim.23108. Epub 2020 Mar 31. PMID: 32236973.
3. Kwon SC, Kim I, Song J, Park J. Does formaldehyde have a causal association with nasopharyngeal cancer and leukaemia? Ann Occup Environ Med. 2018 Jan 31;30:5. doi: 10.1186/s40557-018-0218-z. PMID: 29423228; PMCID: PMC5791191.
4. Blackwell M, Kang H, Thomas A, Infante P. Formaldehyde: evidence of carcinogenicity. Am Ind Hyg Assoc J. 1981 Jul;42(7):A34, A36, A38, passim. PMID: 7018209.
5. Kwak K, Paek D, Park JT. Occupational exposure to formaldehyde and risk of lung cancer: A systematic review and meta-analysis. Am J Ind Med. 2020 Apr;63(4):312-327. doi: 10.1002/ajim.23093. Epub 2020 Jan 30. PMID: 32003024.
6. Halk Sağlığı Genel Müdürlüğü ET: 01.07.2022. EA: https://hsgm.saglik.gov.tr/tr/kanser- nedir-belirtileri.html
7. Global Status Report on Noncommunicable Diseases 2014, WHO, Erişim tarihi: 30.08.2021, http:// apps.who.int/iris/bitstream/handle/10665/148114/ 9789241564854_eng.pdf? sequence
8. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality World wide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4. PMID: 33538338.

9. Wolrd Cancer Research Fund İnternational. Home - Cancer trends - Global cancer data by country AT: 20.09.2022. AA https://www.wcrf.org/cancer-trends/global-cancer-data-by-country/
10. Halk Sağlığı Genel Müdürlüğü ET: 01.07.2022. EA: https://hsgm.saglik.gov.tr/depo/birimler/kanserdb/istatistik/Turkiye_Kanser_Istatistikleri_2016.pdf
11. Çelikgün S., Koç T., Tuncer E., Özer H., Nur N., Cancer Map between 2010-2019 Sivas City. International Journal of Academic Medicine and Pharmacy. 2021; 3 (3); 273-276
12. Çelikgün S, Nur N. 2004-2014 yılında Sivas İlinde görülen kanser vakalarının değerlendirilmesi. ET: 01.07.2022. EA: https://pubmed.ncbi.nlm.nih.gov/30918606/
13. Ekpanyaskul C, Sangrajrang S. Cancer Incidence among Healthcare Workers in Cancer Centers: A 14-Year Retrospective Cohort Study in Thailand. Ann Glob Health. 2018 Aug 31;84(3):429-435. doi: 10.29024/aogh.2324. PMID: 30835381; PMCID: PMC6748292.
14. Ergin, A., Özdilek, R. & Dutucu, N. (2019). 2012-2017 Yılları Arasında Kadınlarda Görülen Kanser Türleri ve Dağılımları: Bir Üniversite Hastanesi Örneği. Kadın Sağlığı Hemşireliği Dergisi, 5 (1), 1-21. Retrievedfromhttps://dergipark.org.tr/tr/pub/kashed/issue/45494/494445
15. Acikgoz A, Yoruk S, Turkmen H, Ergor G. The Relationship between Risk Levels of Breast Cancer and Use of Early Diagnosis and Screening Services in Healthcare Workers in Turkey. Iran J Public Health. 2020 Jul;49(7):1289-1297. doi: 10.18502/ijph.v49i7.3582. PMID: 33083295; PMCID: PMC7548488.
16. WHO Library Cataloguing-in-Publication Data International classification of diseases for oncology (ICD-O) – 3rd edition, 1st revision. 1.Neoplams - classification. I.World Health Organization. II.ICD-O. ISBN 978 92 4 154849 6 (NLM classification: QZ 15) ISBN 978 924 069212 1 (PDF)
17. Kaya ve ark. Knowledge, Attitudes and Behaviors of Health Workers About Cancer Screenings Ankara Med J, Vol. 17, Num. 1, 2017.
18. Kim HL, Park HJ, Sim YH, Choi EY, Shim KW, Lee SW, Lee HS, Chun H. Cancer Prevalence among Physicians in Korea: A Single Center Study. Korean J FamMed. 2016 Mar;37(2):91-6. doi: 10.4082/kjfm.2016.37.2.91. Epub 2016 Mar 25. PMID: 27073607; PMCID: PMC4826997.
19. Shen CT, Hsieh HM, Pan CH, Wu MT, Chuang YS. BreastCancer Risk Among Female Health Professionals: A 35-Year Population-Based Longitudinal Cohort Study in Taiwan. Am J PrevMed. 2021 Dec;61(6):831-840. doi: 10.1016/j.amepre.2021.05.024. Epub 2021 Aug 9. PMID: 34384653.
20. Shen CC, Hu YW, Hu LY, Perng CL, Su TP, Teng CJ, et all. the risk of cancer among Taiwanese female registered nurses: a nationwide retrospective study. PLoS One. 2013 Jul 16;8(7):e68420. doi: 10.1371/journal.pone.0068420. PMID: 23874621; PMCID: PMC3713041.
21. Kjaer TK, Hansen J. Cancer incidence among large cohort of female Danish registered nurses. Scand J Work Environ Health. 2009 Dec;35(6):446-53. doi: 10.5271/sjweh.1358. Epub 2009 Oct 1. PMID: 19806273.
22. Rix, B. A., & Lynge, E. (1996). Cancer incidence in Danish health care workers. Scandinavian Journal of Social Medicine, 24(2), 114–120. doi:10.1177/140349489602400205
23. Engel C, Rasanayagam S. “Working Women and Breast Cancer: The State of the Evidence” http://www.breastcancerfund.org/assets/pdfs/ publications/working-women-and-breast-cancer.pdf
24. Jia Y, Lu Y, Wu K, ve ark. “Does night work increase the risk of breast cancer? A systematic review and metaanalysis of epidemiological studies.” Cancer Epidemiology. 2013;37: 197-206
25. Brophy JT, Keith MM, Watterson A ve ark. “Breast Cancer Risk in Relation to Occupations with Exposure to Carcinogens and Endocrine Disruptors: A Canadian Case-Control Study” Environmental Health, 2012;11(87): 1-17.
26. Labrèche F. “Occupations and Breast Cancer: Evaluation of associations between breast cancer and workplace exposures” http://www.canoshweb.org/sites/canoshweb.org/files/odp/html/breastca.htm (12/11/2015)
27. Davas, A. (2015). Kadın Sağlık Çalışanlarında Meme Kanseri Meslek Hastalığı Olarak Kabul Edilmeli Mi? Mesleki Sağlık ve Güvenlik Dergisi. 19-23
28. Hlalker H, Weiner J. The cancer and work environment register. Arbete och Halsa 9. Soh: Arbetarskyddsverket, 1984
29. Brown, Shannon Cameron, RisaAlberts, and Mark Schoenberg. "Cancer incidence and mortality among workers exposed to benzidine." American journal of industrial medicine 54.4 (2011): 300-306.
30. Chou LB, Chandran S, Harris AH, Tung J, Butler LM. “Increased breast cancer prevalence among female orthopedic surgeons” Journal of Womens Health (Larchmont), 2012;21(6):683-689.
31. https://gco.iarc.fr/today/data/factsheets/populations/792-turkey-fact-sheets.pdf