Evaluation of Socio-demographic Factors and Comorbidities in Adult Hemophilia Patients

Year 2024, , 483 - 489, 31.05.2024

Fatma Keklik Karadağ , Zühal Demirci , Fatoş Dilan Köseoğlu , Güray Saydam , Fahri Şahin

https://doi.org/10.30621/jbachs.1416117

Abstract

Evaluation of Socio-demographic Factors and Comorbidities in Adult Hemophilia Patients

Abstract

Purpose: The association between socio-demographic factors and hemophilia status and the prevalence of comorbidities were evaluated.
Material and Methods: Patients with hemophilia A (n=111) and B (n=24) who were filled a questionnaire form about their sociodemographic factors were included in our study. Factor and inhibitor levels, comorbidities, factor replacement therapies, hemophilic arthropathy, viral status and annual bleeding episodes were recorded.
Results: Median age was 39 years in 135 hemophilia patients and 63.1 % of all the patients had severe hemophilia which was significantly higher among hemophilia A patients (p=0.002). Most of the patients (74.8%) were treated with prophylactic factor replacement therapy. Inhibitor status was positive in 8.9% of all patients. Unemployment rate was found 33.3%. Annual bleeding episodes were higher in patients who had a job. Most of the patients (60 %) were graduated from at least high school. The prevalence of cardiovascular disease, hypertension, diabetes mellitus and obesity were 6.7%; 17.8%, 13.3%, 11.9% respectively. Although there is no association between the obesity and annual bleeding episodes, right ankle was the most affected joint in overweight/obese patients.
Conclusion: Age-related comorbidities and the relation of hemophilia status and social life are needed to be more investigated.

Keywords

Hemophilia, comorbidity, sociodemographic, adult

Ethical Statement

The study was approved by Ege University, Clinical Research Ethics Committee (Date: 09.08.2016, Decision No: 16-7/1).

Supporting Institution

The authors declare no conflict of interest.

Thanks

None

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