Peripheral Blood Cell Changes And Outcomes After Partial Splenic Embolization For Hypersplenism İn Cirrhotic Patients

Abstract

Peripheral Blood Cell Changes And Outcomes After Partial Splenic Embolization For Hypersplenism İn Cirrhotic Patients

Abstract

Background and Purpose: Partial splenic embolization is a common treatment for hypersplenism in patients with cirrhosis. In this investigation, we evaluated the effectiveness and safety of partial splenic embolization in patients with cirrhosis. Methods: We retrospectively investigated 17 patients with hypersplenism secondary to cirrhosis who underwent partial splenic embolization. Following partial splenic embolization, peripheral blood cell counts were measured at regular intervals over a period of twelve months.Post-procedural complications were recorded. Results: This study included 17 individuals, with a mean age of 54.5 ± 10 years. Hemoglobin, platelet, neutrophil, lymphocyte, and white blood cell counts showed statistically significant increases.when compared to the pre-procedure levels at each time point (pre-procedure vs. 1st day p<0.001; pre-procedure vs. 1st week p<0.001; pre-procedure vs. 1st month p<0.001; pre-procedure vs. 6th month p<0.001; pre-procedure vs. 1st year p<0.001). The most common complication was post-embolization syndrome (88.2%), which was managed with conservative treatment. One patient died of esophageal variceal bleeding. Conclusion: Partial splenic embolization improves long-term hematological parameters, with manageable side effects

Keywords

• Partial splenic embolization
• cirrhosis
• hypersplenism

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