A Case Report of a Pregnant Woman with Chronic Hepatit B: Use of Tenofovir in Pregnancy

Abstract

Objective: To overview the effects of tenofovir use in chronic Hepatit B in pregnancy and asses the effects on the vertical transmission of HBV from mother to baby. Case Report: We presented a pregnant woman who has Chronic Hepatit B with high viral load in the 26th week of her pregnancy. She took tenofovir in the 37th week of her pregnancy once a day along six days. Then she gave birth to a healthy baby at the 37th week of the pregnancy. Hepatit B Immunoglobulin HBIG and Hepatit B vaccine had applied to the baby. In the follow-up, the mother’s viral load was decreased. HBV DNA was not detected in the baby. Conclusion: Only six-day tenofovir use in this pregnant woman with chronic Hepatit B may contribute to preventing vertical transmission of HBV from mother to baby. However, the importance of HBIG and vaccination should not be forgotten

Keywords

• Tenofovir,chronic Hepatit B,pregnancy,vertical transmission

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