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Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan

Year 2017, , 61 - 65, 01.09.2017
https://doi.org/10.5152/jbachs.2017.144

Abstract

Purpose: This study aimed to determine factors that affected the development of new onset cardiovascular events among patients with end-stage renal disease ESRD undergoing hemodialysis HD at the Khartoum HD centers in Sudan.Methods: A prospective observational study was conducted among anemic ESRDpatients undergoing HD at Khartoum State HD centers. A total of 1015 patients undergoing HD were recruited from 12 HD centers. A standardized data collection form was used for collecting the required data. Logistic regression analysis was performed.Results: Of 1015 recruited patients, 534 52.6% were included in the final analysis; the 481 patients who were excluded comprised 194 19.1% patients who were transferred to other centers, 165 16.3% who died, 84 8.3% who were lost during follow-up, and 38 3.7% who underwent renal transplantation. The significant factors that affected the development of new cardiovascular events in 154 28.8% anemic ESRD patients were advanced age [for patients aged 45-64 years: odds ratio OR , 1.94; 95% confidence interval CI , 1.18-3.18; p=0.009 and for patients aged ≥65 years: OR, 10.88; 95% CI, 6.12-19.33; p

References

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  • Pisoni RL, Bragg-Gresham JL, Young EW, et al. Anemia manage- ment and outcomes from 12 countries in the dialysis outcomes and practice patterns study (DOPPS). Am J Kidney Dis 2004; 44:94-111. [CrossRef]
  • Finkelstein FO, Story K, Firanek C, et al. Health-related quality of life and hemoglobin levels in chronic kidney disease patients. Clin J Am Soc Nephrol 2009; 4:33-38. [CrossRef]
  • Borghi, L, Meschi T, Guerra A, Briganti A, Schianchi T, Allegri F. He- moglobin variability in nondialysis chronic kidney disease: exam- ining the association with mortality. Clin J Am Soc Nephrol 2009; 4:1176-1182. [CrossRef]
  • Anderson G, Steinberg EP, Whittle J, Powe NR, Antebi S, Herbert R. Development of clinical and economic prognoses from Medicare claims data. JAMA 1990; 263:967-972. [CrossRef]
  • Wilson PW, D’agostino RB, Levy D, Belanger AM, Silbershatz H, Kan- nel WB. Prediction of coronary heart disease using risk factor cate- gories. Circulation J 1998; 97:1837-1847. [CrossRef]
  • Sarnak MJ, Levey AS. Cardiovascular disease and chronic re- nal disease: a new paradigm. Am J Kidney Dis 2000; 35:117-131. [CrossRef]
  • Sliwa K, Wilkinson D, Hansen C, et al. Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study. Lancet J 2008; 371:915-922. [CrossRef]
  • Silva LS, Oliveira RA, Silva GB, et al. Cardiovascular disease in pa- tients with end-stage renal disease on hemodialysis in a develop- ing country. Saudi J Kidney Dis Transpl 2012; 23:262-266.
  • Li S, Foley R, Collins A. Anemia and cardiovascular disease, hos- pitalization,end stage renal disease, and death in older patients with chronic kidney disease. Geriatr Nephrol Urol 2005; 37:395-402. [CrossRef]
  • Charlton KE, Steyn K, Levitt NS, et al. Diet and blood pressure in South Africa: Intake of foods containing sodium, potassium, calcium, and magnesium in three ethnic groups. Nutrition J 2005; 21:39-50. [CrossRef]
  • Mensah GA. Ischaemic heart disease in Africa. Heart 2008; 94:836- 843. [CrossRef]
  • Kendrick J, Chonchol MB. Nontraditional risk factors for cardiovas- cular disease in patients with chronic kidney disease. Nat Clin Pract Nephrol 2008; 4:672-681. [CrossRef]
  • Census. The 5th Sudan population and housing census-2008, prior- ity results 2009; Population Census Council, 2008.
  • Dupont W, Plummer W. PS power and sample size program avail- able for free on the internet. Controlled Clin Trials 1997-2009. Version 3.1.2.
  • Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N & Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999; 130:461-470. [CrossRef]
  • World Health Organization. Global data on Body mass index, Body mass index (BMI) classification. World Health Organization 2006 [cited 23 March 2014; Available from: http://apps.who.int/bmi/in- dex.jsp?introPage=intro_3.html.
  • Kidney Disease, Improving Global Outcomes (KDIGO) Anemia Work Group. KIDGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Kidney Int Suppl 2012; 2:279-335.
  • Field A. Discovering statistics using SPSS. 2nd ed. London: SAGE Publications LTD; 2005.
  • Tong J, Liu M, Li H, et al. Mortality and Associated Risk Factors in Dialysis Patients with Cardiovascular Disease. Kidney Blood Press Res 2016; 41:479-487. [CrossRef]
  • USRDS. USRDS Annual Data Report: Epidemiology of Kidney Dis- ease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2015; [Accessed 20 March 2016]; Available from: https:// www.usrds.org/2015/view/v2_06.aspx.
  • Banaga AS, Mohammed EB, Siddig RM, et al. Causes of end stage renal failure among haemodialysis patients in Khartoum State/Su- dan. BMC Res Notes 2015; 8:502. [CrossRef]
  • Khalil SI. Cardiovascular disease in Sudan: Past, present and future prospects. Sudan Heart J 2013; 1.
  • Hallan SI, Matsushita K, Sang Y, et al. Age and association of kidney measures with mortality and end-stage renal disease. JAMA 2012; 308:2349-2360. [CrossRef]
  • Yilmaz FM, Yilmaz G, Duranay M, et al. Cardiovascular risk factors in hemodialysis and peritoneal dialysis patients. Scand J Clin Lab Invest Suppl 2005; 65:739-745. [CrossRef]
  • Singh AK, Szczech L, Tang KL, et al. Correction of Anemia with Epo- etin Alfa in Chronic Kidney Disease (CHIOR). N Engl J Med 2006; 355:2085-2098. [CrossRef]
  • Rule AD, Bergstralh EJ, Melton LJ, Li X, Weaver AL, Lieske JC. Kid- ney Stones and the Risk for Chronic Kidney Disease. Clin J Am Soc Nephrol 2009; 4:804-811. [CrossRef]
  • Elsharif M, Elsharif E. Causes of end-stage renal disease in Sudan: a single-center experience. Saudi J Kidney Dis Transpl 2011; 22:373-6.
  • Ferraro PM, Taylor EN, Eisner BH, et al. History of kidney stones and the risk of coronary heart disease JAMA 2013; 310:408-415. [CrossRef]
  • Liu Y, Li S, Zeng Z, et al. Kidney stones and cardiovascular risk:A Meta analysis of Cohort Studies. Am J Kidney Dis 2014; 64:402-410. [CrossRef]
  • Glover LM, Bass MA, Carithers T, et al. Association of kidney stones with atherosclerotic cardiovascular disease among adults in the United States: Considerations by race-ethnicity. Physiol. Behav 2016; 157:63-66. [CrossRef]
  • Reiner AP, Kahn A, Eisner BH, et al. Kidney stones and subclinical atherosclerosis in young adults: the CARDIA study. J Urol 2011; 185:920-925. [CrossRef]
  • Lomashvili KA, Narisawa S, Millán JL. Vascular calcification is dependent on plasma levels of pyrophosphate. Kidney Int 2014; 85:1351-1356. [CrossRef]
  • Hadi HA, Carr CS, Al Suwaidi J. Endothelial dysfunction: cardiovas- cular risk factors, therapy, and outcome. Vasc Health Risk Manag 2005; 1:183-198.
  • Madore F, Stampfer MJ, Willett WC, Speizer FE & Curhan GC. Neph- rolithiasis and risk of hypertension in women. Am J Kidney Dis 1998; 32:802-807. [CrossRef]
  • Borghi L, Meschi T, Guerra A, et al. Essential arterial hypertension and stone disease. Kidney Int 1999; 55:2397-406. [CrossRef]
  • Domingos F, Serra A. Nephrolithiasis is associated with an in- creased prevalence of cardiovascular disease. Nephrol Dial Trans- plant 2011; 26:864-868. [CrossRef]
Year 2017, , 61 - 65, 01.09.2017
https://doi.org/10.5152/jbachs.2017.144

Abstract

References

  • National Kidney Foundation, K/DOQI Clinical Practice Guidelines for Anemia of Chronic Kidney Disease, 2000. Am J Kidney Dis 2001; 37:182-238. [CrossRef]
  • Pisoni RL, Bragg-Gresham JL, Young EW, et al. Anemia manage- ment and outcomes from 12 countries in the dialysis outcomes and practice patterns study (DOPPS). Am J Kidney Dis 2004; 44:94-111. [CrossRef]
  • Finkelstein FO, Story K, Firanek C, et al. Health-related quality of life and hemoglobin levels in chronic kidney disease patients. Clin J Am Soc Nephrol 2009; 4:33-38. [CrossRef]
  • Borghi, L, Meschi T, Guerra A, Briganti A, Schianchi T, Allegri F. He- moglobin variability in nondialysis chronic kidney disease: exam- ining the association with mortality. Clin J Am Soc Nephrol 2009; 4:1176-1182. [CrossRef]
  • Anderson G, Steinberg EP, Whittle J, Powe NR, Antebi S, Herbert R. Development of clinical and economic prognoses from Medicare claims data. JAMA 1990; 263:967-972. [CrossRef]
  • Wilson PW, D’agostino RB, Levy D, Belanger AM, Silbershatz H, Kan- nel WB. Prediction of coronary heart disease using risk factor cate- gories. Circulation J 1998; 97:1837-1847. [CrossRef]
  • Sarnak MJ, Levey AS. Cardiovascular disease and chronic re- nal disease: a new paradigm. Am J Kidney Dis 2000; 35:117-131. [CrossRef]
  • Sliwa K, Wilkinson D, Hansen C, et al. Spectrum of heart disease and risk factors in a black urban population in South Africa (the Heart of Soweto Study): a cohort study. Lancet J 2008; 371:915-922. [CrossRef]
  • Silva LS, Oliveira RA, Silva GB, et al. Cardiovascular disease in pa- tients with end-stage renal disease on hemodialysis in a develop- ing country. Saudi J Kidney Dis Transpl 2012; 23:262-266.
  • Li S, Foley R, Collins A. Anemia and cardiovascular disease, hos- pitalization,end stage renal disease, and death in older patients with chronic kidney disease. Geriatr Nephrol Urol 2005; 37:395-402. [CrossRef]
  • Charlton KE, Steyn K, Levitt NS, et al. Diet and blood pressure in South Africa: Intake of foods containing sodium, potassium, calcium, and magnesium in three ethnic groups. Nutrition J 2005; 21:39-50. [CrossRef]
  • Mensah GA. Ischaemic heart disease in Africa. Heart 2008; 94:836- 843. [CrossRef]
  • Kendrick J, Chonchol MB. Nontraditional risk factors for cardiovas- cular disease in patients with chronic kidney disease. Nat Clin Pract Nephrol 2008; 4:672-681. [CrossRef]
  • Census. The 5th Sudan population and housing census-2008, prior- ity results 2009; Population Census Council, 2008.
  • Dupont W, Plummer W. PS power and sample size program avail- able for free on the internet. Controlled Clin Trials 1997-2009. Version 3.1.2.
  • Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N & Roth D. A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group. Ann Intern Med 1999; 130:461-470. [CrossRef]
  • World Health Organization. Global data on Body mass index, Body mass index (BMI) classification. World Health Organization 2006 [cited 23 March 2014; Available from: http://apps.who.int/bmi/in- dex.jsp?introPage=intro_3.html.
  • Kidney Disease, Improving Global Outcomes (KDIGO) Anemia Work Group. KIDGO Clinical Practice Guideline for Anemia in Chronic Kidney Disease. Kidney Int Suppl 2012; 2:279-335.
  • Field A. Discovering statistics using SPSS. 2nd ed. London: SAGE Publications LTD; 2005.
  • Tong J, Liu M, Li H, et al. Mortality and Associated Risk Factors in Dialysis Patients with Cardiovascular Disease. Kidney Blood Press Res 2016; 41:479-487. [CrossRef]
  • USRDS. USRDS Annual Data Report: Epidemiology of Kidney Dis- ease in the United States. Bethesda, MD: National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases. 2015; [Accessed 20 March 2016]; Available from: https:// www.usrds.org/2015/view/v2_06.aspx.
  • Banaga AS, Mohammed EB, Siddig RM, et al. Causes of end stage renal failure among haemodialysis patients in Khartoum State/Su- dan. BMC Res Notes 2015; 8:502. [CrossRef]
  • Khalil SI. Cardiovascular disease in Sudan: Past, present and future prospects. Sudan Heart J 2013; 1.
  • Hallan SI, Matsushita K, Sang Y, et al. Age and association of kidney measures with mortality and end-stage renal disease. JAMA 2012; 308:2349-2360. [CrossRef]
  • Yilmaz FM, Yilmaz G, Duranay M, et al. Cardiovascular risk factors in hemodialysis and peritoneal dialysis patients. Scand J Clin Lab Invest Suppl 2005; 65:739-745. [CrossRef]
  • Singh AK, Szczech L, Tang KL, et al. Correction of Anemia with Epo- etin Alfa in Chronic Kidney Disease (CHIOR). N Engl J Med 2006; 355:2085-2098. [CrossRef]
  • Rule AD, Bergstralh EJ, Melton LJ, Li X, Weaver AL, Lieske JC. Kid- ney Stones and the Risk for Chronic Kidney Disease. Clin J Am Soc Nephrol 2009; 4:804-811. [CrossRef]
  • Elsharif M, Elsharif E. Causes of end-stage renal disease in Sudan: a single-center experience. Saudi J Kidney Dis Transpl 2011; 22:373-6.
  • Ferraro PM, Taylor EN, Eisner BH, et al. History of kidney stones and the risk of coronary heart disease JAMA 2013; 310:408-415. [CrossRef]
  • Liu Y, Li S, Zeng Z, et al. Kidney stones and cardiovascular risk:A Meta analysis of Cohort Studies. Am J Kidney Dis 2014; 64:402-410. [CrossRef]
  • Glover LM, Bass MA, Carithers T, et al. Association of kidney stones with atherosclerotic cardiovascular disease among adults in the United States: Considerations by race-ethnicity. Physiol. Behav 2016; 157:63-66. [CrossRef]
  • Reiner AP, Kahn A, Eisner BH, et al. Kidney stones and subclinical atherosclerosis in young adults: the CARDIA study. J Urol 2011; 185:920-925. [CrossRef]
  • Lomashvili KA, Narisawa S, Millán JL. Vascular calcification is dependent on plasma levels of pyrophosphate. Kidney Int 2014; 85:1351-1356. [CrossRef]
  • Hadi HA, Carr CS, Al Suwaidi J. Endothelial dysfunction: cardiovas- cular risk factors, therapy, and outcome. Vasc Health Risk Manag 2005; 1:183-198.
  • Madore F, Stampfer MJ, Willett WC, Speizer FE & Curhan GC. Neph- rolithiasis and risk of hypertension in women. Am J Kidney Dis 1998; 32:802-807. [CrossRef]
  • Borghi L, Meschi T, Guerra A, et al. Essential arterial hypertension and stone disease. Kidney Int 1999; 55:2397-406. [CrossRef]
  • Domingos F, Serra A. Nephrolithiasis is associated with an in- creased prevalence of cardiovascular disease. Nephrol Dial Trans- plant 2011; 26:864-868. [CrossRef]
There are 37 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Omalhassan Amir This is me

Azmi Sarriff This is me

Mohamed Babikir Abdelraheem This is me

Amer Hayat Khan This is me

Bachok Norsa’adah This is me

Publication Date September 1, 2017
Published in Issue Year 2017

Cite

APA Amir, O., Sarriff, A., Abdelraheem, M. B., Khan, A. H., et al. (2017). Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan. Journal of Basic and Clinical Health Sciences, 1(3), 61-65. https://doi.org/10.5152/jbachs.2017.144
AMA Amir O, Sarriff A, Abdelraheem MB, Khan AH, Norsa’adah B. Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan. JBACHS. September 2017;1(3):61-65. doi:10.5152/jbachs.2017.144
Chicago Amir, Omalhassan, Azmi Sarriff, Mohamed Babikir Abdelraheem, Amer Hayat Khan, and Bachok Norsa’adah. “Factors Affecting the Development of Cardiovascular Events Among Patients With End-Stage Renal Disease Undergoing Hemodialysis in Sudan”. Journal of Basic and Clinical Health Sciences 1, no. 3 (September 2017): 61-65. https://doi.org/10.5152/jbachs.2017.144.
EndNote Amir O, Sarriff A, Abdelraheem MB, Khan AH, Norsa’adah B (September 1, 2017) Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan. Journal of Basic and Clinical Health Sciences 1 3 61–65.
IEEE O. Amir, A. Sarriff, M. B. Abdelraheem, A. H. Khan, and B. Norsa’adah, “Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan”, JBACHS, vol. 1, no. 3, pp. 61–65, 2017, doi: 10.5152/jbachs.2017.144.
ISNAD Amir, Omalhassan et al. “Factors Affecting the Development of Cardiovascular Events Among Patients With End-Stage Renal Disease Undergoing Hemodialysis in Sudan”. Journal of Basic and Clinical Health Sciences 1/3 (September 2017), 61-65. https://doi.org/10.5152/jbachs.2017.144.
JAMA Amir O, Sarriff A, Abdelraheem MB, Khan AH, Norsa’adah B. Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan. JBACHS. 2017;1:61–65.
MLA Amir, Omalhassan et al. “Factors Affecting the Development of Cardiovascular Events Among Patients With End-Stage Renal Disease Undergoing Hemodialysis in Sudan”. Journal of Basic and Clinical Health Sciences, vol. 1, no. 3, 2017, pp. 61-65, doi:10.5152/jbachs.2017.144.
Vancouver Amir O, Sarriff A, Abdelraheem MB, Khan AH, Norsa’adah B. Factors Affecting the Development of Cardiovascular Events Among Patients with End-Stage Renal Disease Undergoing Hemodialysis in Sudan. JBACHS. 2017;1(3):61-5.