Current Ablation Type Surgical Treatment Modalities in Treatment-Resistant Major Depression: Review of The Recent Major Surgical Series

Year 2019, Volume: 3 Issue: 1, 1 - 8, 01.03.2019

Bulent Bakar Cansel Cetin Jonathan Oppong Ahmet Melih Erdogan

https://doi.org/10.30621/jbachs.2019.452

Cited By: 2

Abstract

Purpose: Major depression is currently a disease with high morbidity and mortality rates. About 20% of patients have treatment-resistant major depression TRMD . This article which consisted of a recent large clinical case series reported in medical literature is constituted to screen ablative surgical treatment methods and their safety and efficacy in patients with TRMD.Methods: Four types of ablative surgical modality i. e. anterior cingulotomy, anterior capsulotomy, subcaudate tractotomy, limbic leucotomy in TRMD patients were evaluated and patients’ data which was used to describe the basis of radiologic and operative procedures and findings, and outcome was obtained from PubMed/Medline database between years 2000–2018.Results: In literature, studies showed that about 40–60% of patients had complete remission and 35% of patients showed partial remission following anterior cingulotomy. It was reported that approximately 50% of patients were responsive and 40% of patients were remission following anterior capsulotomy. Studies demonstrated that about 55–75% of patients were responsive to treatment after performing subcaudate tractotomy. Long term clinical recovery was seen 36–76% of patients applied limbic leucotomy in literature.Conclusion: In conclusion, the long term therapeutic effects and mechanism of action of these surgical techniques that were used last two decades in the management of patients with TRMD are still under investigation and the need for research on the long-term benefits of these surgical modalities should be considered

Keywords

cingulotomy, capsulotomy, subcaudate tractotomy, limbic leucotomy, treatment-resistant major depression

References

• Volpini M, Giacobbe P, Cosgrove GR, Levitt A, Lozano AM, lipsman n. The history and future of ablative neurosurgery for major depressive disorder. Stereotact Funct Neurosurg 2017;95:216–228. [CrossRef]
• Christmas D, Eljamel MS, Butler S, et al. Long term outcome of thermal anterior capsulotomy for chronic, treatment refractory depression. J Neurol Neurosurg Psychiatry 2011;82:594–600. [CrossRef]
• Lapidus KA, Kopell BH, Ben-Haim S, Rezai AR, Goodman WK. History of psychosurgery: a psychiatrist’s perspective. World Neurosurg 2013;80:S27.e1–16. [CrossRef]
• Leiphart JW, Valone FH 3rd. Stereotactic lesions for the treatment of psychiatric disorders. J Neurosurg 2010;113:1204–1211.
• Luigjes J, de Kwaasteniet BP, de Koning PP, et al. Surgery for psychiatric disorders. World Neurosurg 2013;80:S31.e17–28. [CrossRef]
• Sachdev PS, Chen X. Neurosurgical treatment of mood disorders: traditional psychosurgery and the advent of deep brain stimulation. Curr Opin Psychiatry 2009;22:25–31. [CrossRef]
• Kim MC, Lee TK, Choi CR. Review of long-term results of stereotactic psychosurgery. Neurol Med Chir (Tokyo) 2002;42:365–371. [CrossRef]
• Christmas D, Matthews K. Neurosurgical treatments for patients with chronic, treatment-refractory depression: a retrospective, consecutive, case series comparison of anterior capsulotomy, anterior cingulotomy and vagus nerve stimulation. Stereotact Funct Neurosurg 2015;93:387–392. [CrossRef]
• Eljamel MS. Ablative neurosurgery for mental disorders: is there still a role in the 21st century? A personal perspective. Neurosurg Focus 2008;25:E4. [CrossRef]
• Hurwitz TA, Honey CR, Allen J, et al. Bilateral anterior capsulotomy for intractable depression. J Neuropsychiatry Clin Neurosci 2012;24:176– 182. [CrossRef]
• Steele JD, Christmas D, Eljamel MS, Matthews K. Anterior cingulotomy for major depression: clinical outcome and relationship to lesion characteristics. Biol Psychiatry 2008;63:670–677. [CrossRef]
• Ridout N, O’Carroll RE, Dritschel B, Christmas D, Eljamel M, Matthews K. Emotion recognition from dynamic emotional displays following anterior cingulotomy and anterior capsulotomy for chronic depression. Neuropsychologia 2007;45:1735–1743. [CrossRef]
• Montoya A, Weiss AP, Price BH, et al. Magnetic resonance imaging- guided stereotactic limbic leukotomy for treatment of intractable psychiatric disease. Neurosurgery 2002;50:1043–1052. [CrossRef]
• Shields DC, Asaad W, Eskandar EN, et al. Prospective assessment of stereotactic ablative surgery for intractable major depression. Biol Psychiatry 2008;64:449–454. [CrossRef]
• Kelly D, Richardson A, Mitchell-Heggs N. Stereotactic limbic leucotomy: neurophysiological aspects and operative technique. Br J Psychiatry 1973;123:133–140. [CrossRef]
• Subramanian L, Bracht T, Jenkins P, et al. Clinical improvements following bilateral anterior capsulotomy in treatment-resistant depression. Psychol Med 2017;47:1097–1106. [CrossRef]
• Hodgkiss AD, Malizia AL, Bartlett JR, Bridges PK. Outcome after the psychosurgical operation of stereotactic subcaudate tractotomy, 1979–1991. J Neuropsychiatry Clin Neurosci 1995;7:230–234. [CrossRef]
• Kelly D, Richardson A, Mitchell-Heggs N, Greenup J, Chen C, Hafner RJ. Stereotactic limbic leucotomy: a preliminary report on forty patients. Br J Psychiatry 1973;123:141–148. [CrossRef]
• Kelly D, Mitchell-Heggs N. Stereotactic limbic leucotomy - a follow- up study of thirty patients. Postgrad Med J 1973;49:865–882. [CrossRef]
• Krack P, Hariz MI, Baunez C, Guridi J, Obeso JA. Deep brain stimulation: from neurology to psychiatry? Trends Neurosci 2010;33:474–484. [CrossRef]
• Richter EO, Davis KD, Hamani C, Hutchison WD, Dostrovsky JO, Lozano AM. Cingulotomy for psychiatric disease: microelectrode guidance, a callosal reference system for documenting lesion location, and clinical results. Neurosurgery 2008;62(6 Suppl 3):622– 630. [CrossRef]
• Aydin S, Abuzayed B. Psychosurgery: review of latest concepts and applications. J Neurol Surg A Cent Eur Neurosurg 2013;74:29–46. [CrossRef]
• Gentil AF, Eskandar EN, Marci CD, Evans KC, Dougherty DD. Physiological responses to brain stimulation during limbic surgery: further evidence of anterior cingulate modulation of autonomic arousal. Biol Psychiatry 2009;66:695–701. [CrossRef]
• Shah DB, Pesiridou A, Baltuch GH, Malone DA, O’Reardon JP. Functional neurosurgery in the treatment of severe obsessive compulsive disorder and major depression: overview of disease circuits and therapeutic targeting for the clinician. Psychiatry (Edgmont) 2008;5:24–33.
• Heilbronner SR, Haber SN. Frontal cortical and subcortical projections provide a basis for segmenting the cingulum bundle: implications for neuroimaging and psychiatric disorders. J Neurosci 2014;34:10041– 10054. [CrossRef]
• Gasquoine PG. Localization of function in anterior cingulate cortex: from psychosurgery to functional neuroimaging. Neurosci Biobehav Rev 2013;37:340–348. [CrossRef]
• Steele JD, Currie J, Lawrie SM, Reid I. Prefrontal cortical functional abnormality in major depressive disorder: a stereotactic meta- analysis. J Affect Disord 2007;101:1–11. [CrossRef]
• Bridges PK, Bartlett JR, Hale AS, Poynton AM, Malizia AL, Hodgkiss AD. Psychosurgery: stereotactic subcaudate tractomy. An indispensable treatment. Br J Psychiatry 1994;165:599–611. [CrossRef]
• Andrade P, Noblesse LH, Temel Y, et al. Neurostimulatory and ablative treatment options in major depressive disorder: a systematic review. Acta Neurochir (Wien) 2010;152:565–577. [CrossRef]
• Rizvi SJ, Donovan M, Giacobbe P, Placenza F, Rotzinger S, Kennedy SH. Neurostimulation therapies for treatment resistant depression: a focus on vagus nerve stimulation and deep brain stimulation. Int Rev Psychiatry 2011;23:424–436. [CrossRef]
• Rush AJ, George MS, Sackeim HA, et al. Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study. Biol Psychiatry 2000;47:276–286. [CrossRef]
• Rush AJ, Marangell LB, Sackeim HA, et al. Vagus nerve stimulation for treatment-resistant depression: a randomized, controlled acute phase trial. Biol Psychiatry 2005;58:347–354. [CrossRef]
• Morishita T, Fayad SM, Higuchi MA, Nestor KA, Foote KD. Deep brain stimulation for treatment-resistant depression: systematic review of clinical outcomes. Neurotherapeutics 2014;11:475–484.
• Lozano AM, Mayberg HS, Giacobbe P, Hamani C, Craddock RC, Kennedy SH. Subcallosal cingulate gyrus deep brain stimulation for treatment-resistant depression. Biol Psychiatry 2008;64:461–467. [CrossRef] https://doi.org/10.1016/j.biopsych.2008.05.034
• Kennedy SH, Giacobbe P, Rizvi SJ, et al. Deep brain stimulation for treatment-resistant depression: follow-up after 3 to 6 years. Am J Psychiatry 2011;168:502–510. [CrossRef]
• Malone DA Jr, Dougherty DD, Rezai AR, et al. Deep brain stimulation of the ventral capsule/ventral striatum for treatment-resistant depression. Biol Psychiatry 2009;65:267–275. [CrossRef]
• Narang P, Retzlaff A, Brar K, Lippmann S. Deep brain stimulation for treatment-refractory depression. South Med J 2016;109:700–703. [CrossRef]