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Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis

Year 2024, Volume: 8 Issue: 1, 200 - 205, 31.01.2024
https://doi.org/10.30621/jbachs.1379119

Abstract

Background and Purpose: Some have proposed that the cardiovascular risk among individuals with DH differs from that of the general population. This study aimed to analyze cardiovascular risk factors in DH patients and compare them to a matched control group without DH or celiac disease.

Methods: This was a retrospective hospital-based study involving patients diagnosed with DH, both clinically and histopathologically, along with age- and sex-matched control subjects without the disease. The presence of ischemic heart disease, and the risk factors including laboratory values, treatment and comorbidity histories were evaluated comparatively. (SPSS version 28.0).

Results: Thirty-five patients with DH and 49 controls were included. No significant difference was found between the DH patients and controls regarding the prevalence of ischemic heart disease (22.9% vs. 14.3%, p:0.312). Diabetes mellitus was significantly higher and HDL cholesterol levels were significantly lower in the DH group (respectively, p: 0.044 and p: 0.018). Celiac autoantibodies, the laboratory values, or treatments did not show any significant correlation with heart disease in DH.

Conclusion: This study revealed that HDL cholesterol were significantly lower in DH patients compared to general population. More research is needed to optimize the cardiovascular health of DH patients.

References

  • UpToDate [Internet]. Dermatitis herpetiformis. [Accessed date: 24 August 2023]. Available from: https://www.uptodate.com/contents/dermatitis-herpetiformis.
  • Conroy M, Allen N, Lacey B, Soilleux E, Littlejohns T. Association between coeliac disease and cardiovascular disease: prospective analysis of UK Biobank data. BMJ Med 2023;2(1):e000371.
  • Nilsson N, Leivo J, Collin P, et al. Risk of vascular diseases in patients with dermatitis herpetiformis and coeliac disease: a long-term cohort study. Ann Med 2023;55(1):2227423.
  • Holmes GKT, Muirhead A. Mortality in coeliac disease: a population-based cohort study from a single centre in Southern Derbyshire, UK. BMJ Open Gastroenterol 2018;5(1):e000201.
  • Lear JT, Neary RH, Jones P, Fitzgerald DA, English JSC. Risk factors for ischaemic heart disease in patients with dermatitis herpetiformis. J R Soc Med 1997;90(5):247-249.
  • Pillan MN, Spandrio S, Sleiman I, Meini A, Scalvini T, Balestrieri GP. Effects of a gluten-free diet on serum lipids and lipoprotein (a) levels in a group of patients with celiac disease. J Pediatr Gastroenterol Nutr 1994;18(2):183-185.

Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis

Year 2024, Volume: 8 Issue: 1, 200 - 205, 31.01.2024
https://doi.org/10.30621/jbachs.1379119

Abstract

References

  • UpToDate [Internet]. Dermatitis herpetiformis. [Accessed date: 24 August 2023]. Available from: https://www.uptodate.com/contents/dermatitis-herpetiformis.
  • Conroy M, Allen N, Lacey B, Soilleux E, Littlejohns T. Association between coeliac disease and cardiovascular disease: prospective analysis of UK Biobank data. BMJ Med 2023;2(1):e000371.
  • Nilsson N, Leivo J, Collin P, et al. Risk of vascular diseases in patients with dermatitis herpetiformis and coeliac disease: a long-term cohort study. Ann Med 2023;55(1):2227423.
  • Holmes GKT, Muirhead A. Mortality in coeliac disease: a population-based cohort study from a single centre in Southern Derbyshire, UK. BMJ Open Gastroenterol 2018;5(1):e000201.
  • Lear JT, Neary RH, Jones P, Fitzgerald DA, English JSC. Risk factors for ischaemic heart disease in patients with dermatitis herpetiformis. J R Soc Med 1997;90(5):247-249.
  • Pillan MN, Spandrio S, Sleiman I, Meini A, Scalvini T, Balestrieri GP. Effects of a gluten-free diet on serum lipids and lipoprotein (a) levels in a group of patients with celiac disease. J Pediatr Gastroenterol Nutr 1994;18(2):183-185.
There are 6 citations in total.

Details

Primary Language English
Subjects Dermatology
Journal Section Research Article
Authors

Fatmagül Gülbaşaran 0000-0002-7550-6052

Özlem Özbağcivan 0000-0001-7190-3969

Doğuhan Çil 0009-0009-0095-1889

Mehmet Birhan Yılmaz 0000-0002-8169-8628

Early Pub Date January 31, 2024
Publication Date January 31, 2024
Submission Date October 20, 2023
Acceptance Date December 12, 2023
Published in Issue Year 2024 Volume: 8 Issue: 1

Cite

APA Gülbaşaran, F., Özbağcivan, Ö., Çil, D., Yılmaz, M. B. (2024). Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis. Journal of Basic and Clinical Health Sciences, 8(1), 200-205. https://doi.org/10.30621/jbachs.1379119
AMA Gülbaşaran F, Özbağcivan Ö, Çil D, Yılmaz MB. Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis. JBACHS. January 2024;8(1):200-205. doi:10.30621/jbachs.1379119
Chicago Gülbaşaran, Fatmagül, Özlem Özbağcivan, Doğuhan Çil, and Mehmet Birhan Yılmaz. “Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients With Dermatitis Herpetiformis”. Journal of Basic and Clinical Health Sciences 8, no. 1 (January 2024): 200-205. https://doi.org/10.30621/jbachs.1379119.
EndNote Gülbaşaran F, Özbağcivan Ö, Çil D, Yılmaz MB (January 1, 2024) Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis. Journal of Basic and Clinical Health Sciences 8 1 200–205.
IEEE F. Gülbaşaran, Ö. Özbağcivan, D. Çil, and M. B. Yılmaz, “Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis”, JBACHS, vol. 8, no. 1, pp. 200–205, 2024, doi: 10.30621/jbachs.1379119.
ISNAD Gülbaşaran, Fatmagül et al. “Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients With Dermatitis Herpetiformis”. Journal of Basic and Clinical Health Sciences 8/1 (January 2024), 200-205. https://doi.org/10.30621/jbachs.1379119.
JAMA Gülbaşaran F, Özbağcivan Ö, Çil D, Yılmaz MB. Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis. JBACHS. 2024;8:200–205.
MLA Gülbaşaran, Fatmagül et al. “Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients With Dermatitis Herpetiformis”. Journal of Basic and Clinical Health Sciences, vol. 8, no. 1, 2024, pp. 200-5, doi:10.30621/jbachs.1379119.
Vancouver Gülbaşaran F, Özbağcivan Ö, Çil D, Yılmaz MB. Retrospective Evaluation of Risk Factors for Ischemic Heart Disease in Patients with Dermatitis Herpetiformis. JBACHS. 2024;8(1):200-5.