Is the occurrence of Gestational Diabetes Mellitus in pregnancies higher following In Vitro Fertilization treatment? Why? A retrospective cohort study

Year 2024, Volume: 8 Issue: 3, 750 - 758, 30.09.2024

Nuran Nur Aypar Akbağ , Merlinda Aluş Tokat , Sevcan Özöztürk , Elif Ünsal Avdal , Recep Emre Okyay , Ömer Erbil Doğan

https://doi.org/10.30621/jbachs.1543485

Abstract

Purpose: This study aim to determine the occurrence of gestational diabetes mellitus (GDM) in pregnancies after IVF treatment and to evaluate the factors that reduce this risk.
Material and Methods: This retrospective cohort study was conducted using the medical records of pregnant women who conceived following IVF at the in-vitro fertilization center between 2002–2019. The data were obtained from medical records and phone interviews. Univariate and multivariate logistic regression analyses were performed.
Results: The incidence of GDM was found to be 16.7%. The regression model indicated that the risk of GDM was 4.57 times higher in the age group 36–40 at conception during the IVF cycle than the age group 31–35 (95% CI = 1.18–17.73, p = .028). Furthermore, women who conceived after the second IVF trial had a risk of GDM 3.464 times higher than those that conceived after their first IVF trial (95% CI = 1.07–11.23, p= .038).
Conclusion: As age and number of IVF trials increase in infertile women, the risk of GDM increases after IVF treatment.

Keywords

Gestational Diabetes Mellitus, In Vitro Fertilization, Risk Factors

Ethical Statement

Approval was gained for ethical compliance from the non-invasive Research Ethics Committee of the Dokuz Eylul University (2019 / 10–23).

Supporting Institution

No

Project Number

No

Thanks

None

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