Acute kidney injury due to rhabdomyolysis after status epilepticus: Two pediatric case reports

Year 2013, , 517 - 520, 01.12.2013

Ahmet Midhat Elmacı Fatih Akın Erhan Aksoy

https://doi.org/10.5799/ahinjs.01.2013.04.0337

Abstract

Rhabdomyolysis is defined as degeneration of skeletal muscle due to traumatic or non-traumatic causes. With the injury of sarcolemma, myocyte contents (myoglobin, enzymes and electrolytes) leakage into the plasma and urine occurs. If rhabdomyolysis is not recognized and untreated, severe even fatal complications such as acute kidney injury (AKI), hypocalcemia, hyperkalemia, hypovolemia, muscle necrosis, cardiac arrythmias and compartment syndrome may occur. Status epilepticus is an uncommon cause of rhabdomyolysis and myoglobinuria. We report here two pediatric patients, who developed myoglobinuria and AKI due to status epilepticus. J Clin Exp Invest 2013; 4 (4): 517-520

Keywords

Epilepsy, child, rhabdomyolysis, kidney injury

Acute kidney injury due to rhabdomyolysis after status epilepticus: Two pediatric case reports

Abstract

Rabdomiyoliz, travmatik veya non-travmatik sebeplerle çizgili kas hücrelerinin hasara uğramasıdır. Hasar sonrası kas hücre içeriği (miyoglobin, enzim ve elektrolitler) dolaşıma katılır. Rabdomiyoliz teşhis ve tedavi edilmezse akut böbrek hasarı (ABH), hipokalsemi, hiperkalemi, hipovolemi, kas nekrozu, kardiyak aritmi ve kompartman sendromu gibi ciddi komplikasyonlara neden olabilir. Status epileptikus, rabdomiyoliz ve miyoglobinürinin nadir sebeplerindendir. Bu yazıda status epileptikus sonrası miyoglobinüri ve ABH gelişen iki pediatrik olgu sunulmuştur.

Keywords

Epilepsi, çocuk, rabdomiyoliz, böbrek hasarı

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