İntravitreal Anti-VEGF enjeksiyonu sonrası göz içi basınç ve oküler aksiyel uzunluk değişiklikleri

Öz

Amaç: İntravitreal anti-vasküler endotelyal growth faktör (anti-VEGF) enjeksiyonu sonrası göziçi basıncı (GİB) ve oküler aksiyel uzunluk (AU) değişikliklerinin değerlendirilmesi. Yöntemler: Kliniğimizde intravitreal bevacizumab veya ranibizumab enjeksiyonu uygulanan hastalar prospektif olarak değerlendirildi. GİB, Tono-Pen kullanılarak ve oküler AU, ultrason biyometri kullanılarak, enjeksiyondan önce (GİB0, AU0), enjeksiyondan 1 dakika (GİB1, AU1) ve 24 saat (GİB2, AU2) sonra ölçüldü. Artmış GİB ve AU ile ilişkili faktörler lojistik regresyon analizi kullanılarak incelendi. Bulgular: Ortalama yaş 66,7±12 olup 53\'ü (%55) erkek ve 43\'ü (%45) kadın olmak üzere toplam 96 hasta değerlendirildi. GİB0\'ın 15,2±3,5 mmHg\'dan, 22,2±8,6 mmHg\'ya (GİB1) yükseldiği görülmüştür (p

Anahtar Kelimeler

• İntravitreal enjeksiyon, intraoküler basınç, oküler aksiyel uzunluk.

Alterations in intraocular pressure and ocular axial length after intravitreal Anti-VEGF injection

Abstract

Objective: To evaluate the effect of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection on intraocular pressure (IOP) and ocular axial length (AL). Methods: A prospective series of consecutive patients undergoing injection of intravitreal bevacizumab or ranibizumab in our clinic was investigated. IOP was measured with Tono-Pen and ocular AL with ultrasound biometry before (IOP0, AL0) and about 1 min (IOP1, AL1) and 24 hours (IOP2, AL2) after intravitreal injection. Logistic regression analysis was used to investigate factors (lens status, presence of glaucoma and previous intravitreal injection) associated with increased IOP and AL. Results: We recruited 96 patients with a mean age of 66.7±12 years, 53 (55%) men and 43 (45%) women. One minute after the injection (IOP1), mean IOP increased from 15.2±3.5 mmHg (IOP0) to 22.2±8.6 mmHg (p

Keywords

• Intravitreal injection, intraocular pressure, ocular axial length.

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