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Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia

Year 2013, , 136 - 140, 01.06.2013
https://doi.org/10.5799/ahinjs.01.2013.02.0253

Abstract

Objectives: We intended to examine 541 brucellosis cases by offering our experiences regarding this preventable infectious disease that is significant for our country. Methods: We evaluated 1210 hospitalized patients between the dates of January 2006 and December 2010 in Siirt General Hospital and 541 brucellosis cases were reviewed retrospectively. Patients with Rose Bengal plate test positive and has Wright agglutination test a titer of 1:160 or higher were included in this study. Results: A 53.6% of brucellosis cases were male and 46.4% were female. The mean age (±SD) of patients was 41.23±2.7 years. Between the ages 31 and 50 is the range brucellosis is most commonly encountered in both men and women. Hematological evidence discovered that for 67% of patient\'s sedimentation is 20-40 mm/hour, 53% leukocyte count is in normal range, 36% of patients had leukocytosis, 10% had leukopenia, and 8% had thrombocytopenia. Most common three symptoms were joint pain (90%), myalgia (75%) and fatigue (70%). The most involved systems were musculoskeletal (28%), hematological (22%), and gastrointestinal systems (20%). Most commonly encountered systemic findings were sacroiliitis (20%), anemia (14%) and liver dysfunction (12%). Brucella was observed most commonly is May (30%) in Siirt. A 47% of our cases are occupied in agriculture and stockbreeding that are risky occupations regarding brucellosis, supports the conventional data regarding brucellosis epidemiology. Conclusion: Despite the campaigns, infection rate is still high and it affects both animal industry and human health in our country. Data about brucellosis should be validated by large multicenter studies. J Clin Exp Invest 2013; 4 (2): 136-140

Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia

Year 2013, , 136 - 140, 01.06.2013
https://doi.org/10.5799/ahinjs.01.2013.02.0253

Abstract

Amaç: Ülkemiz açısından önem arz eden ve önlenebilir bir enfeksiyon olan bruselloz ile ilgili deneyimlerimizi sunarak konuyu irdelemek amacıyla 541 bruselloz olgusu değerlendirilmiştir. Yöntemler: Ocak 2006-Aralık 2010 tarihleri arasında yatırılarak takip ve tedavileri yapılan 1210 hasta geriye dönük olarak incelenmiş, Rose Bengal pozitif ve Wright aglutinasyon testi titresi 1/160 ve üzeri olan 541 bruselloz olgusu çalışmaya dahil edilmiştir. Bulgular: Çalışmamıza alınan 541olgunun %53,6\'sı erkek %46,4\'ü kadın olup, yaş ortalamaları 41,23±2,7 idi. Hem erkeklerde hem de kadınlarda brusellozun en sık görüldüğü yaş aralığı 31-50 yaş arası olmuştur. Hematolojik bulgulardan hastaların %67\'sinde sedimentasyon 20-40 mm/saat, %53\'ünde lökosit sayısı normal aralıkta iken, hastaların %36\'sında lökositoz, %10\'unda lökopeni, %8\'inde trombositopeni bulunmuştur. En sık gözlenen üç semptom eklem ağrısı (%90), kas ağrısı (%75) ve halsizlik (%70) olmuştur. En sık tutulan sistemler sırasıyla kas iskelet (%28), hematolojik (%22) ve gastrointestinal sistemler (%20) olmuştur. Kas iskelet sistemi bulgularından sakroileit (%20), hematolojik bulgulardan anemi (%14) ve gastrointestinal sistemden ise karaciğer fonksiyon bozukluğu (%12) en sık raslanan sistemik bulgular olmuştur. Bu endemik hastalığın en çok (%30) gözlemlendiği ay Mayıs olmuştur. Olgularımızın %47\'sinin bruselloz açısından riskli meslek olan tarım ve hayvancılıkla uğraşıyor olması, bruselloz epidemiolojisi hakkındaki klasik bilgileri destekler niteliktedir. Sonuç: Önleyici programlara rağmen bu enfeksiyonun oranı hala yüksek olup, hem insan sağlığını hem de hayvancılık sektörünü etkiler. Bundan dolayı bu yaygın enfeksiyon hastalığı ile ilgili daha geniş serilerin irdelendiği çalışmalara ihtiyaç duyulmaktadır.

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Details

Primary Language Turkish
Journal Section Research Article
Authors

Fatih Demircan This is me

Fırat Zafer Mengeloğlu This is me

Faruk Kılınç This is me

Affan Denk This is me

Publication Date June 1, 2013
Published in Issue Year 2013

Cite

APA Demircan, F., Mengeloğlu, F. Z., Kılınç, F., Denk, A. (2013). Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia. Journal of Clinical and Experimental Investigations, 4(2), 136-140. https://doi.org/10.5799/ahinjs.01.2013.02.0253
AMA Demircan F, Mengeloğlu FZ, Kılınç F, Denk A. Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia. J Clin Exp Invest. June 2013;4(2):136-140. doi:10.5799/ahinjs.01.2013.02.0253
Chicago Demircan, Fatih, Fırat Zafer Mengeloğlu, Faruk Kılınç, and Affan Denk. “Evaluation of Epidemiological Data of 541 Patients With Brucellosis in Siirt, a City in South-Eastern Anatolia”. Journal of Clinical and Experimental Investigations 4, no. 2 (June 2013): 136-40. https://doi.org/10.5799/ahinjs.01.2013.02.0253.
EndNote Demircan F, Mengeloğlu FZ, Kılınç F, Denk A (June 1, 2013) Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia. Journal of Clinical and Experimental Investigations 4 2 136–140.
IEEE F. Demircan, F. Z. Mengeloğlu, F. Kılınç, and A. Denk, “Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia”, J Clin Exp Invest, vol. 4, no. 2, pp. 136–140, 2013, doi: 10.5799/ahinjs.01.2013.02.0253.
ISNAD Demircan, Fatih et al. “Evaluation of Epidemiological Data of 541 Patients With Brucellosis in Siirt, a City in South-Eastern Anatolia”. Journal of Clinical and Experimental Investigations 4/2 (June 2013), 136-140. https://doi.org/10.5799/ahinjs.01.2013.02.0253.
JAMA Demircan F, Mengeloğlu FZ, Kılınç F, Denk A. Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia. J Clin Exp Invest. 2013;4:136–140.
MLA Demircan, Fatih et al. “Evaluation of Epidemiological Data of 541 Patients With Brucellosis in Siirt, a City in South-Eastern Anatolia”. Journal of Clinical and Experimental Investigations, vol. 4, no. 2, 2013, pp. 136-40, doi:10.5799/ahinjs.01.2013.02.0253.
Vancouver Demircan F, Mengeloğlu FZ, Kılınç F, Denk A. Evaluation of epidemiological data of 541 patients with brucellosis in Siirt, a city in south-eastern Anatolia. J Clin Exp Invest. 2013;4(2):136-40.