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Anesthetic management in an appendix tumor patient undergoing hyperthermic chemotherapy

Year 2013, , 234 - 237, 01.06.2013
https://doi.org/10.5799/ahinjs.01.2013.02.0274

Abstract

Cytoreductive surgery combined with hyperthermic intra­peritoneal chemotherapy (HIPEC) is a complex and mul­tidiscipliner procedure that is being used increasingly for peritoneal and appendix malignency. First of all the mac­roscopic tumor tissues are extracted after that peritoneal perfusion is started with giving heated 42°C chemother­apeutic solution via abdominal drains. It is important to maintain normovolemia, to regulate coagulation and renal parameters during perioperative period, to compansate hypothermia during cytoreductive surgery and hyperther­mia during HIPEC and to regulate hemodynamic changes due to increased abdominal pressure during HIPEC. In this case report, we aimed to share anaesthetic experi­ence and to evaluate anaesthetic problems in 45 years old ASA I patient undergoing cytoreductive surgery and hypertermic intraperitoneal chemotherapy in which newly established in our hospital for appendix tumor. J Clin Exp Invest 2013; 4 (2): 234-237

References

  • Bell JC, Rylah BG, Chambers RW, et al.Perioperatif manegement of patients undergoing cytoreduc- tive surgery combined with heated intraperitoneal chemotherapy for peritoneal surface malinency:A multi-ınstitutional experience. Ann Surg Oncol 2012;19:4244-4251.
  • Glockzin G, Schlitt HJ, Piso P. Peritoneal carcinoma- tosis: patient selection, perioperative complications and quality of life related to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. World J Surgical Oncol 2009;7:5-8.
  • Yonemura Y, Elnemr A, Endou Y, et al. Multidisci- pliplinary therapy for treatment of patients with peri- toneal carsinomatosis from gastric cancer.World J Gastrointest Oncol 2010;15;2:85-97.
  • Schmidt C, Creutzenberg M, Hobbhahn J, Bucher M. Peri-operative anaesthetic management of cytoreduc- tive surgery with hyperthermic intraperitoneal chemo- therapy. Anaesthesia 2008;63:389-95.
  • Pretto G, Grando M, Junior NC, Bergold RA, de Castro RAC,Santiago A. Anesthesia for peritonectomy with hyperthermic intraperitoneal chemotherapy.Case re- port. Rev Bras de Anesthesiol 2010;60:551-557.
  • Tang L, Mei LJ, Yang XJ, et al. Cytoreductive surgery plus intraperitoneal chemotherapy improves survival of gasric cancer with peritoneal carcinamatosis:evidence from an experimental study. J Translat Med 2011;9:53- 7.
  • Scumann R, Wilson G, Hariskov S, et al. Impact of in- traoperative anesthetic and fluid management on 30- day postoperative outcomes in a newly established peritoneal surface malignancy program. J Anesth Clin Res 2012;3:244-248.

Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım

Year 2013, , 234 - 237, 01.06.2013
https://doi.org/10.5799/ahinjs.01.2013.02.0274

Abstract

Sitoredüktif cerrahi ile birlikte uygulanan hipertermik intra­peritoneal kemoterapi (HİPEK), peritoneal ve apandise ait malignitelerde gittikçe artan oranda kullanılan, kompleks ve multidisipliner bir yöntemdir. Önce görülebilen bütün tümör dokuları çıkarılır, daha sonra 42°C\'ye ısıtılmış ke­moterapötik solüsyon, drenler yolu ile batına verilerek pe­ritoneal perfüzyon yapılır. Perioperatif dönemde normo­voleminin sürdürülmesi, sitoredüktif faz sırasında hipoter­minin, HİPEK sırasında hiperterminin kompanse edilmesi ve intraabdominal basıncın artmasına bağlı ortaya çıkan hemodinamik değişikliklerin regüle edilmesi, koagülasyon ve renal parametrelerin takip edilerek düzeltilmesi önem­lidir. Biz de nüks apandis müsinöz tümörü nedeniyle sitoredük­tif cerrahi ve HİPEK planlanan 45 yaşındaki ASA I erkek hastamız nedeniyle, hastanemizde yeni yapılmaya başla­nan bu yöntem konusundaki deneyimimizi paylaşmayı ve anestezi açısından oluşabilecek sorunları gözden geçir­meyi amaçladık.

References

  • Bell JC, Rylah BG, Chambers RW, et al.Perioperatif manegement of patients undergoing cytoreduc- tive surgery combined with heated intraperitoneal chemotherapy for peritoneal surface malinency:A multi-ınstitutional experience. Ann Surg Oncol 2012;19:4244-4251.
  • Glockzin G, Schlitt HJ, Piso P. Peritoneal carcinoma- tosis: patient selection, perioperative complications and quality of life related to cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. World J Surgical Oncol 2009;7:5-8.
  • Yonemura Y, Elnemr A, Endou Y, et al. Multidisci- pliplinary therapy for treatment of patients with peri- toneal carsinomatosis from gastric cancer.World J Gastrointest Oncol 2010;15;2:85-97.
  • Schmidt C, Creutzenberg M, Hobbhahn J, Bucher M. Peri-operative anaesthetic management of cytoreduc- tive surgery with hyperthermic intraperitoneal chemo- therapy. Anaesthesia 2008;63:389-95.
  • Pretto G, Grando M, Junior NC, Bergold RA, de Castro RAC,Santiago A. Anesthesia for peritonectomy with hyperthermic intraperitoneal chemotherapy.Case re- port. Rev Bras de Anesthesiol 2010;60:551-557.
  • Tang L, Mei LJ, Yang XJ, et al. Cytoreductive surgery plus intraperitoneal chemotherapy improves survival of gasric cancer with peritoneal carcinamatosis:evidence from an experimental study. J Translat Med 2011;9:53- 7.
  • Scumann R, Wilson G, Hariskov S, et al. Impact of in- traoperative anesthetic and fluid management on 30- day postoperative outcomes in a newly established peritoneal surface malignancy program. J Anesth Clin Res 2012;3:244-248.
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Yonca Yanlı This is me

Erdem Akçay This is me

Cafer Yürük This is me

Nurten Bakan This is me

Publication Date June 1, 2013
Published in Issue Year 2013

Cite

APA Yanlı, Y., Akçay, E., Yürük, C., Bakan, N. (2013). Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım. Journal of Clinical and Experimental Investigations, 4(2), 234-237. https://doi.org/10.5799/ahinjs.01.2013.02.0274
AMA Yanlı Y, Akçay E, Yürük C, Bakan N. Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım. J Clin Exp Invest. June 2013;4(2):234-237. doi:10.5799/ahinjs.01.2013.02.0274
Chicago Yanlı, Yonca, Erdem Akçay, Cafer Yürük, and Nurten Bakan. “Hipertermik Kemoterapi Uygulanan Apandis tümörü hastasında Anestezik yaklaşım”. Journal of Clinical and Experimental Investigations 4, no. 2 (June 2013): 234-37. https://doi.org/10.5799/ahinjs.01.2013.02.0274.
EndNote Yanlı Y, Akçay E, Yürük C, Bakan N (June 1, 2013) Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım. Journal of Clinical and Experimental Investigations 4 2 234–237.
IEEE Y. Yanlı, E. Akçay, C. Yürük, and N. Bakan, “Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım”, J Clin Exp Invest, vol. 4, no. 2, pp. 234–237, 2013, doi: 10.5799/ahinjs.01.2013.02.0274.
ISNAD Yanlı, Yonca et al. “Hipertermik Kemoterapi Uygulanan Apandis tümörü hastasında Anestezik yaklaşım”. Journal of Clinical and Experimental Investigations 4/2 (June 2013), 234-237. https://doi.org/10.5799/ahinjs.01.2013.02.0274.
JAMA Yanlı Y, Akçay E, Yürük C, Bakan N. Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım. J Clin Exp Invest. 2013;4:234–237.
MLA Yanlı, Yonca et al. “Hipertermik Kemoterapi Uygulanan Apandis tümörü hastasında Anestezik yaklaşım”. Journal of Clinical and Experimental Investigations, vol. 4, no. 2, 2013, pp. 234-7, doi:10.5799/ahinjs.01.2013.02.0274.
Vancouver Yanlı Y, Akçay E, Yürük C, Bakan N. Hipertermik kemoterapi uygulanan apandis tümörü hastasında anestezik yaklaşım. J Clin Exp Invest. 2013;4(2):234-7.