Primitive neuroectodermal tumor of the posterior mandible: A case report

Abstract

Primitive neuroectodermal tumor is a term used to de­scribe a category of neoplasms of neuroectodermal ori­gin with variable cell differentiation. These tumors arise in many places throughout the body. The chest wall, larynx, abdomen, and pelvis being the most common primary sites; in rare cases, they occur in the head and neck area. Only 3% of cases have been reported within the skull and jaws. In this report, a rare case of primitive neuroectoder­mal tumor in the left side posterior mandible in a young adult is described. J Clin Exp Invest 2013; 4 (1): 101-104

Keywords

• Neuroectodermal tumors, primitive, periph­eral, oral cavity, mandible

Posterior mandibulanın primitif nöroektodermal tümörü: Olgu sunumu

Abstract

Primitif nöroektodermal tümör, nöroektodermal kaynaklı değişik hücre farklılaşması ile birlikte olan bir neoplazm kategorisini tanımlamak için kullanılan bir terimdir. Bu tü­mörler vücutta birçok yerden kaynak alır. Göğüs duvarı, larinks, karın ve pelvis en sık tutulan bölgeler olup, nadi­ren baş ve boyun bölgesinde oluşur. Olguların yalnızca %3\'ü kafatası ve çeneden köken alır. Bu raporda genç bir erişkinde mandibula sol arka kısmında gelişmiş nadir bir nöroektodermal tümör olgusu sunulmaktadır.

Keywords

• Nöroektodermal tümörler, primitif, periferik, ağız içi, mandibula

References

1. Mills S. Neuroectodermal neoplasms of head and neck with emphasis on neuroectodocrine carcinoma. Mod Pathol 2002;5:264-278.
2. Chowdhury K, Manoukian JJ, Rochon L, et al. Ex- tracranial primitive neuroectodermal tumor of the head and neck. Arch Otolaryngol Head Neck Surg 1990;116:475-478.
3. Helsel JC, Mrak RE, Hanna E et al. Peripheral primitive neuroectodermal tumor of the parotid gland region: report of a case with fine-needle aspiration findings. Diag Cytopathol 2000;22:161-166.
4. Hyun CB, Lee YR, Bemiller TA. Metastatic peripheral primitive neuroectodermal tumor (PNET) masquerad- ing as liver abscess. J Clin Gastroenterol 2002;35:93- 97.
5. Jones JE, McGill T. Peripheral primitive neuroectoder- mal tumors of the head and neck. Arch Otolaryngol Head Neck Surg 1995;121:1392-1395.
6. Kao SY, Yang J, Yang AH, et al. Peripheral primitive neuroectodermal tumor of the maxillary gingivae with metastasis to cervical lymph nodes: report of a case. J Oral Maxillofac Surg 2002;60:821-825.
7. Votta TJ, Fantuzzo JJ, Boyd BC. Peripheral neuroecto- dermal tumor associated with the anterior mandible: a case report and review of the literature. Oral Surg Oral Med Oral Path Oral Radiol Endod 2005;105:592-597.
8. Garcia AG, Pereira C. Primitive neuroectodermal tu- mor of the upper jaw. J Oral Maxill Fac Surg 1999; 57: 616-623.

9. Pereira CM, Alves F. Mouth metastasis of periph- eral primitive neuroectodermal tumor, Oral Disease 2005;11:44-45.
10. Stout AP. A tumor of the ulnar nerve. Proc NY Pathol Soc 1918;12:2-12.
11. Kahn HJ, Thorner PS. Monoclonal antibody MB2: A potential marker for Ewing’s sarcoma and primitive neuroectodermal tumor. Pediatr Pathol 1989;9:153- 162.
12. de Alava E, Gerald WL. Molecular biology of the Ew- ing’s sarcoma/primitive neuroectodermal tumor fam- ily. J Clin Oncol 2000;18:204-213.
13. Jurgens H, Bier V. Malignant peripheral neuroecto- dermal tumors a retrospective analysis of 42 patients. Cancer 1988;61:349-357.
14. Hollis LJ, Poole S. Primitive neuroectodermal tumor of masseter muscle. J Laryngol Otol 1996; 27:1179.
15. Jurgens H, Bier V, Harma D, Beck J. Malignant periph- eral neuroectodermal tumors: a retrospective analysis of 42 patients. Cancer 1988;61:349-357.