Recurrent Guillain-Barré syndrome associated with idiopathic thrombocytopenic purpura

Abstract

Guillain-Barré syndrome (GBS) usually present with acute inflammatory polyradiculoneuropathy having clinical features of rapid and progressive weakness at the limbs, symmetric decrease or loss of tendon reflexes. The exact mechanism of clinical picture is not well known but immune factors are blamed. Patients having GBS have an recurrence rate ranging between 1% and 10%. Idiopathic thrombocytopenic purpura (ITP) is an acquired systemic disease presented with mild to severe thrombocytopenia. The patient who followed with ITP diagnosis for 12 years underwent 2 times GBS attacks within 2-year interval. We would like to present this case due to rare association of ITP diagnosis & GBS attacks. J Clin Exp Invest 2012; 3(2): 284-286

Keywords

• Guillain-Barré syndrome, Idiopathic thrombocytopenic purpura, recurrent.

Recurrent Guillain-Barré syndrome associated with idiopathic thrombocytopenic purpura

Abstract

Guillain-Barré sendromu (GBS), genellikle hızlı ve ilerleyici giden, asendan simetrik kuvvet kaybı ve arefleksi ile karakterize akut enflamatuar polinradikülonöropatidir. Klinik tablonun gelişim mekanizması tam olarak bilinmemekle birlikte immun faktörler suçlanmaktadır. GBS geçiren hastaların %1-10\'unda tekrarlama ihtimali vardır. İdiyopatik trombositopenik purpura (İTP), ortadan şiddetliye kadar değişebilen trombositopeninin eşlik ettiği edinsel sistemik bir hastalıktır. 12 yıldır İTP tanısıyla takip edilirken, 2 yıl arayla GBS geçiren olgu nadir gözlendiği için sunulacaktır.

Keywords

• Guillain-Barré sendromu, idiyopatik trombositopenik purpura, tekrarlayan

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