Kikuchi-Fujimoto disease: Case report

Abstract

Kikuchi-Fujimoto disease is rare self-limiting disease with unknown etiology characterized by fever and lymphadenopathy. Laboratory findings are non-specific. Although, viral, chemical agents, and autoimmunity are suggested in etiology, exact cause has not been identified. It is often misdiagnosed as malign lymphoma. Histologically, involved nodes show localized proliferation of histiocytes and immunoblast associated with abundant nuclear debris and tissue necrosis. In this article, 29 years-old female patient applied with neck lymphadenopathy diagnosed as Kikuchi-Fujimoto disease is discussed. J Clin Exp Invest 2011; 2 (4): 433-436

Keywords

• Kikuchi-Fujimoto disease, lymphadenopathy, neck mass

Kikuchi-Fujimoto Hastalığı: Olgu Sunumu

Öz

Kikuchi-Fujimoto hastalığı etiyolojisi belli olmayan, kendiliğinden düzelen, ateş ve lenfadenopati ile karakterize nadir bir hastalıktır. Laboratuar bulgularında belirgin bir özellik göstermez. Etiyolojisi konusunda çeşitli viral, kimyasal ajanlar ve otoimmunite suçlansa da esas neden bilinmemektedir. Sıklıkla malign lenfoma ile karışmaktadır. Histopatolojik olarak lenf düğümlerinde histiosit ve immunoblastların lokalize proliferasyonu ile bol miktarda nukleer debris ve doku nekrozu izlenir. Bu makalede, kliniğimize boyunda lenfadenopati ile başvuran ve Kikuchi-Fujimoto hastalığı tanısı konan, 29 yaşında kadın hasta tartışıldı.

Anahtar Kelimeler

• Kikuchi-Fujimoto hastalığı, lenfadenopati, boyun kitlesi

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