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Kikuchi-Fujimoto disease: Case report

Year 2011, , 433 - 436, 01.12.2011
https://doi.org/10.5799/ahinjs.01.2011.04.0088

Abstract

Kikuchi-Fujimoto disease is rare self-limiting disease with unknown etiology characterized by fever and lymphadenopathy. Laboratory findings are non-specific. Although, viral, chemical agents, and autoimmunity are suggested in etiology, exact cause has not been identified. It is often misdiagnosed as malign lymphoma. Histologically, involved nodes show localized proliferation of histiocytes and immunoblast associated with abundant nuclear debris and tissue necrosis. In this article, 29 years-old female patient applied with neck lymphadenopathy diagnosed as Kikuchi-Fujimoto disease is discussed. J Clin Exp Invest 2011; 2 (4): 433-436

References

  • Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phago- cytes: a clinicopathological study. Acta Hematol Jpn 1972;35(3):379-80.
  • Wustenberg EG, Theissig F, Offergeld C, Huttenbrink KB. Necrotizing lymphadenitis (Kikuchi-Fujimoto dis- ease) as a rare cause of cervical lymphadenopathies. Diagnosis and differential diagnosis. Laryngorhinoot- ologie 2000; 79(2):93-5
  • Aslan V, Bildirici K, Eren Ö, Gülbaş Z. Kikuchi-Fujimoto Hastalığı: Olgu sunumu. Türkiye Ekopatoloji Dergisi 2001 7(1-2) 46-8.
  • Yoshino T, Mannami T, Ichimura K, Takenaka K, Nose S, Yamadori I, Akagi T. Two cases of histiocytic ne- crotizing lymphadenitis (Kikuchi-Fujimoto’s disease) following diffuse large B-cell lymphoma. Hum Pathol 2000; 31(10): 1328-31.
  • Huh J, Chi HS, Kim SS, Gong G. A study of the vi- ral etiology of histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease). J Korean Med Sci 1998; 13(1): 27-30.
  • Lorenzo AH, Amat CG, de la Victoria LOM, et al. His- tiocytic necrotizing lymphadenitis: Kikuchi-Fujimoto disease. Apropos of 6 cases. An Med Interna 1999; 16:301-4.
  • Bosch X, Guilabert A. Kikuchi-Fujimoto disease. Or- phanet J Rare Dis 200623;1(1):18-20.
  • Ramirez AL, Johnson J, Murr AH. Kikuchi-Fujimoto’s disease: an easily misdiagnosed clinical entity. Otolar- yngol Head Neck Surg 2001;125(5):651-3.
  • Spies J, Foucar K, Thompson CT, LeBoit PE. The his- topathology of cutaneous lesions of Kikuchi’s disease (necrotizing lymphadenitis): a report of five cases. Am J Surg Pathol 1999; 23(9):1040-7.
  • Jang YJ, Park KH, Seok HJ. Management of Kikuchi’s disease using glucocorticoid. J Laryngol Otol 2000; 114(9): 709-11.
  • Sugiyama A, Araki E, Arakawa K, et al. A case of subacute necrotizing lymphadenitis complicated with brachial plexus neuritis. Rinsho Shinkeigaku 1998; 38(10-11):941-4.

Kikuchi-Fujimoto Hastalığı: Olgu Sunumu

Year 2011, , 433 - 436, 01.12.2011
https://doi.org/10.5799/ahinjs.01.2011.04.0088

Abstract

Kikuchi-Fujimoto hastalığı etiyolojisi belli olmayan, kendiliğinden düzelen, ateş ve lenfadenopati ile karakterize nadir bir hastalıktır. Laboratuar bulgularında belirgin bir özellik göstermez. Etiyolojisi konusunda çeşitli viral, kimyasal ajanlar ve otoimmunite suçlansa da esas neden bilinmemektedir. Sıklıkla malign lenfoma ile karışmaktadır. Histopatolojik olarak lenf düğümlerinde histiosit ve immunoblastların lokalize proliferasyonu ile bol miktarda nukleer debris ve doku nekrozu izlenir. Bu makalede, kliniğimize boyunda lenfadenopati ile başvuran ve Kikuchi-Fujimoto hastalığı tanısı konan, 29 yaşında kadın hasta tartışıldı.

References

  • Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phago- cytes: a clinicopathological study. Acta Hematol Jpn 1972;35(3):379-80.
  • Wustenberg EG, Theissig F, Offergeld C, Huttenbrink KB. Necrotizing lymphadenitis (Kikuchi-Fujimoto dis- ease) as a rare cause of cervical lymphadenopathies. Diagnosis and differential diagnosis. Laryngorhinoot- ologie 2000; 79(2):93-5
  • Aslan V, Bildirici K, Eren Ö, Gülbaş Z. Kikuchi-Fujimoto Hastalığı: Olgu sunumu. Türkiye Ekopatoloji Dergisi 2001 7(1-2) 46-8.
  • Yoshino T, Mannami T, Ichimura K, Takenaka K, Nose S, Yamadori I, Akagi T. Two cases of histiocytic ne- crotizing lymphadenitis (Kikuchi-Fujimoto’s disease) following diffuse large B-cell lymphoma. Hum Pathol 2000; 31(10): 1328-31.
  • Huh J, Chi HS, Kim SS, Gong G. A study of the vi- ral etiology of histiocytic necrotizing lymphadenitis (Kikuchi-Fujimoto disease). J Korean Med Sci 1998; 13(1): 27-30.
  • Lorenzo AH, Amat CG, de la Victoria LOM, et al. His- tiocytic necrotizing lymphadenitis: Kikuchi-Fujimoto disease. Apropos of 6 cases. An Med Interna 1999; 16:301-4.
  • Bosch X, Guilabert A. Kikuchi-Fujimoto disease. Or- phanet J Rare Dis 200623;1(1):18-20.
  • Ramirez AL, Johnson J, Murr AH. Kikuchi-Fujimoto’s disease: an easily misdiagnosed clinical entity. Otolar- yngol Head Neck Surg 2001;125(5):651-3.
  • Spies J, Foucar K, Thompson CT, LeBoit PE. The his- topathology of cutaneous lesions of Kikuchi’s disease (necrotizing lymphadenitis): a report of five cases. Am J Surg Pathol 1999; 23(9):1040-7.
  • Jang YJ, Park KH, Seok HJ. Management of Kikuchi’s disease using glucocorticoid. J Laryngol Otol 2000; 114(9): 709-11.
  • Sugiyama A, Araki E, Arakawa K, et al. A case of subacute necrotizing lymphadenitis complicated with brachial plexus neuritis. Rinsho Shinkeigaku 1998; 38(10-11):941-4.
There are 11 citations in total.

Details

Primary Language Turkish
Journal Section Case Report
Authors

Mehmet Haksever This is me

Hülya Haksever This is me

H. Mete İnançlı This is me

Ümit Tunçel This is me

Füsun Ardıç This is me

Publication Date December 1, 2011
Published in Issue Year 2011

Cite

APA Haksever, M., Haksever, H., İnançlı, H. M., Tunçel, Ü., et al. (2011). Kikuchi-Fujimoto Hastalığı: Olgu Sunumu. Journal of Clinical and Experimental Investigations, 2(4), 433-436. https://doi.org/10.5799/ahinjs.01.2011.04.0088
AMA Haksever M, Haksever H, İnançlı HM, Tunçel Ü, Ardıç F. Kikuchi-Fujimoto Hastalığı: Olgu Sunumu. J Clin Exp Invest. December 2011;2(4):433-436. doi:10.5799/ahinjs.01.2011.04.0088
Chicago Haksever, Mehmet, Hülya Haksever, H. Mete İnançlı, Ümit Tunçel, and Füsun Ardıç. “Kikuchi-Fujimoto Hastalığı: Olgu Sunumu”. Journal of Clinical and Experimental Investigations 2, no. 4 (December 2011): 433-36. https://doi.org/10.5799/ahinjs.01.2011.04.0088.
EndNote Haksever M, Haksever H, İnançlı HM, Tunçel Ü, Ardıç F (December 1, 2011) Kikuchi-Fujimoto Hastalığı: Olgu Sunumu. Journal of Clinical and Experimental Investigations 2 4 433–436.
IEEE M. Haksever, H. Haksever, H. M. İnançlı, Ü. Tunçel, and F. Ardıç, “Kikuchi-Fujimoto Hastalığı: Olgu Sunumu”, J Clin Exp Invest, vol. 2, no. 4, pp. 433–436, 2011, doi: 10.5799/ahinjs.01.2011.04.0088.
ISNAD Haksever, Mehmet et al. “Kikuchi-Fujimoto Hastalığı: Olgu Sunumu”. Journal of Clinical and Experimental Investigations 2/4 (December 2011), 433-436. https://doi.org/10.5799/ahinjs.01.2011.04.0088.
JAMA Haksever M, Haksever H, İnançlı HM, Tunçel Ü, Ardıç F. Kikuchi-Fujimoto Hastalığı: Olgu Sunumu. J Clin Exp Invest. 2011;2:433–436.
MLA Haksever, Mehmet et al. “Kikuchi-Fujimoto Hastalığı: Olgu Sunumu”. Journal of Clinical and Experimental Investigations, vol. 2, no. 4, 2011, pp. 433-6, doi:10.5799/ahinjs.01.2011.04.0088.
Vancouver Haksever M, Haksever H, İnançlı HM, Tunçel Ü, Ardıç F. Kikuchi-Fujimoto Hastalığı: Olgu Sunumu. J Clin Exp Invest. 2011;2(4):433-6.