Coexistance of JAK2V617F mutation and BCR/ABL translocation in one patient

Year 2010, , 138 - 140, 01.06.2010

Osman Yokuş Fatih Kurnaz Özlem Şahin Balçık Burak Uz Murat Albayrak

https://doi.org/10.5799/ahinjs.01.2010.02.0029

Abstract

Keywords

JAK2V617F mutasyonu, BCR/ABL translokasyonu, miyeloproliferatif bozukluklar, miyelofibroz

Coexistance of JAK2V617F mutation and BCR/ABL translocation in one patient

Abstract

liland DG. Expression of Jak2V617F causes a polycthemia vera-like disease with associated myelofibrosis in a murine bone marrow transplant model. Blood 2006;107:4274–81. 4. Jelinek J, Oki Y, Gharibyan V et al. JAK2 mutation 1849G>T is rare in acute leukemias but can be found in CMML, Phil- adelphia chromosome-negative CML, and megakaryocytic leukemia. Blood 2005;106:3370–3

Keywords

JAK2V617F mutation, BCR/ABL translocation, miyeloproliferative disorders, myelofibrosis

References

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