Objective: To measure and compare macular thicknesses
(MT) in patients that have amblyopia and control group eyes with optical
coherence tomography (OCT) and to define OCT as an early diagnosis
tool.
Methods: 27 patients having amblyopia associated
strabismus classified as group 1, 18 patients having amblyopia
associated anisometropia classified as group 2 and 45 healthy volunteers
classified as group 3 were enrolled into the study. All participants
were underwent into the full ophthalmological examination and were
measured MT by OCT.
Results: There was a statistical significance between
control group and group 1 in central MT (p=0.01). But there was no
significant differences between areas as we divided the macular
thicknesses other quadrants. When we compare group 2 and group 3 there
was thinner statistical significance in temporal quadrants (p=0.04).
There was no significant difference between the other quadrants and
central MT (p<0.05). There was significant difference between group 1
and group 2 in central MT (p=0.03). No significant difference was found
between group 1 and group 2 in other quadrants (p<0.05).
Conclusion: Changes in macular thicknesses in
strabismic amblyopia measured by OCT shows that structural changes can
develop in amblyopia. OCT gives hope as early diagnosis tool with the
non-invasive feature in vivo. J Clin Exp Invest 2016; 7 (2): 178-183
Subjects | Health Care Administration |
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Journal Section | Research Article |
Authors | |
Publication Date | June 16, 2016 |
Published in Issue | Year 2016 |