Changing of Uric Acid Levels by Age and Sex in Patients with Diabetes Mellitus

Year 2016, , 1 - 6, 01.03.2016

Nilgün Basaran Osman Evliyaoglu , Veysel Sucu Okan Dikker Leyla Bulut Fatma Tezcan Vesile Kalaslıoğlu Rıza Sandıkçı Müberra Vardar

https://doi.org/10.5799/jcei.328707

Abstract

Objective: We examined the association between uric acid and glycemic status by the aspects of age and sex.
Methods: The retrospective was performed study at Okmeydanı Educate and Research Hospital. All data were obtained
from the patient records. Only one sample of HbA1c or glucose measurement within a year was included. To evaluate
the pattern of glucose control, we categorized the patients according to HbA1c levels and grouped them according to
a range of values. HbA1c was measured by high performance liquid chromatography, routine biochemistry parameters
were determined by photometric method.
Results: Serum uric acid levels showed an increasing trend with the age in female group and this trend became significant
after 30 years old (p<0.001). The significant effect of HbA1c and gender on uric acid levels were determined in the
subjects having no renal failure. There was a significant increase of uric acid levels in prediabetics than normal group
and decrease in unregulated diabetics. But in both sex groups the pattern of changing was different.
Conclusion: In conclusion, we found that age is an important factor examining the serum uric acid levels of female
subjects. The peak values of serum uric acid were detected in prediabetic group in males but in females this peak point
was diabetic group. J Clin Exp Invest 2016; 7 (1): 1-6

Keywords

Diabetes mellitus, uric acid, age, gender

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