Geotrichum candidum: A Rare Infection Agent in Urinary System: Case Report and Review of The Literature

Year 2017, , 127 - 129, 29.12.2017

Fulya Bayındır Bilman , Mevliye Yetik

https://doi.org/10.5799/jcei.382434

Abstract

Geotrichum is a species of fungi that can be found in every
environment in nature, in soil, in water and in air. As it can be found in
plants and in cereals and milk products, it has also been shown to be found in
normal human flora (mucus and faeces). Geotrichum candidum, mostly
saprophytic, can cause clinical picture called Geotrichosis. Neoplasms,
leukosis, HIV infection, diabetes mellitus, and kidney transplantation are
generally the underlying diseases in such cases. In a case in which we detected
G.candidum reproduction in urinary tract infection, we aimed to
present the case with its clinic findings and to review the literature.

Keywords

Geotrichum candidum, Geotrichosis, fungus, immunsupressive host

References

• 1. Larone DH Medically Important Fungi. A Guide to Identification Fifth edn 2011, Washington, DC. American Society for Microbiology. https:// doi.org/10.1128/9781555816605. 2. Walsh TJ, Groll A, Hiemenz J, Fleming R, Roilides E, and Anaissie E. Infections due to emerging and uncommon medically important fungal pathogens. Clin Microbiol and Infect, 2004;10:48–66. 3. Alvarez-Lerma F, Palomar M, Leo´ n C, et al. Fungal colonization and/or infection in intensive care units. Multicenter study of 1,562 patients. Med Clin (Barc). 2003;121:161–6.
• 4. Chitasombat MN, Kofteridis DP, Jiang Y, Tarrand J, Lewis RE, Kontoyiannis DP. Rare opportunistic (non-Candida, non-Cryptococcus) yeast bloodstream infections in patients with cancer. J Infect. 2012;64:68- 75. 5. Verghese, P. Ravichandran. Geotrichum candidum infection in a renal transplant recipient. Indian J Nephrol. 2003;13:72–4.
• 6. André N, Coze C, Gentet JC, Perez R, Bernard JL. Geotrichum candidum septicemia in a child with hepatoblastoma. Pediatr Infect Dis J. 2004;23(1):86.
• 7. Henrich TJ, Mart FM, Milner Jr DA and Thorner AR, Disseminated Geotrichum candidum infection in a patient with relapsed acute myelogenous leukemia following allogeneic stem cell transplantation and review of the literature. Transpl Infect Dis. 2009;11:458–62. 8. García-Lozano T, Sánchez Yepes M, Aznar Oroval E, Ortiz Muñoz BA, Guillén Bernardo I. Intra-abdominal seroma and lymphopenia without leucopenia in a cancer patient. Geotrichum candidum infection. Rev Iberoam Micol. 2014;31:152-3. 9. Myint T, Dykhuizen MJ, McDonald CH, Ribes JA. Post operative fungal endopthalmitis due to Geotrichum candidum. Med Mycol Case Rep. 2015;10:4-6. 10. Mahapatra A. Coinfection of Cryptosporidium and Geotrichum in a case of AIDS. Indian J Pathol Microbiol. 2005;48:25-7.
• 11. Kassamali H, Anaissie E, Ro J, et al. Disseminated Geotrichum candidum infection. J Clin Microbiol. 1987;25:1782–83.
• 12. Prakash PY, Seetaramaiah VK, Thomas J, Khanna V, Rao SP. Renal fungal bezoar owing to Geotrichum candidum. Med Mycol Case Rep. 2012;1:63– 5.
• 13. Hrdy DB, Nassar NN, Rinaldi MG. Traumatic joint infection due to Geotrichum candidum. Clin Infect Dis. 1995;20:468-9.
• 14. Sfakianakis A, Krasagakis K, Stefanidou M, et al. Invasive cutaneous infection with Geotrichum candidum: sequential treatment with amphotericin B and voriconazole. Med Mycol. 2007;45:81-4.