Yedi Yaşında Lupus Nefriti Tanılı Çocuk Vaka

Year 2018, , 39 - 42, 01.04.2018

Manolya Kara Nur Canpolat Işın Kılıçaslan Salim Çalışkan Lale Sever Özgür Kasapçopur

https://doi.org/10.5222/j.child.2018.42104

Abstract

Sistemik lupus eritematozus SLE çocuklarda erişkinler- den daha ender gözlenen otoimmün bir hastalıktır. Hastalık 10 yaşın altındaki çocuklarda özellikle erkeklerde oldukça enderdir. Tüm yaş grupları içinde 16 yaşın üzerinde hasta- lığın gözükme sıklığı %15 civarındadır. Lupus nefriti, has- talığın en ciddi organ tutulumundan biridir. Vakaların yaklaşık %90’ında böbrek tutulumu gözlenmektedir. Lupus nefriti hipertansiyon, proteinüri ve böbrek yetmezliği ile prezente olabileceği gibi asemptomatik de seyredebilir. Seyri sırasında trombotik mikroanjiyopati gibi ağır komp- likasyonlar gelişebilir. Literatürdeki son yayınlara göre böbrek tutulumu çocuklarda daha sık gözlenmektedir. Çocuklarda gelişen lupus nefriti daha ağır seyredebilmek- tedir. Burada, öncesinde yanlışlıkla Henoch Schöenlein Purpura tanısı alan 7 yaşında lupus nefriti vakası sunul- muştur

Keywords

Çocukluk çağı, lupus nefriti, sistemik lupus eritematozus

A Case of Seven-Year-Old Boy with Lupus Nephritis

Abstract

Systemic lupus erythematosus SLE is an autoimmune disorder which is less often observed in children than adults. It is uncommon in children younger than ten years, especi- ally in boys. In all age groups, nearly 15% of all cases have onset of disease over 16 years of age. Lupus nephritis is one of the most serious organ involvements of the disease and its symptoms are generally related to hypertension, proteinuria, and renal failure. But it may be also asymptomatic. Renal disease occurs in 90% of patients in the course of the disease. During its course serious complications as thrombotic mic- roangiopathy. may develop. Recent reports suggest that renal involvement is more frequent in children than in adults. Childhood-onset lupus nephritis can be more severe than the late-onset disease. We present a 7-year-old boy with lupus nephritis who was previously misdiagnosed as Henoch - Schönlein Purpura HSP

Keywords

Childhood, lupus nephritis, systemic lupus erythematosus

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