Pediyatrik Akut Solunum Sıkıntısı Sendromu

Year 2017, , 99 - 102, 01.07.2017

Gürkan Atay Kemal Nişli

https://doi.org/10.5222/j.child.2017.099

Abstract

Akut Solunum Sıkıntısı Sendromu ARDS mortalite ve morbitesi yüksek seyreden, dünya genelinde yaygın ve önemli bir klinik tablodur. Diffüz akciğer parankim infilt- rasyonu ile karekterize hipokseminin ön planda olduğu ARDS hakkında tanımlandığı 1967 yılından beri oldukça fazla araştırma ve uzlaşı raporu yazılmış ve özellikle yetiş- kin akciğer hasarı üzerine odaklanmıştır. Risk faktörleri, etiyoloji, patofizyoloji ve veriler göz önüne alındığında çocukluk yaş grubunu tam olarak kapsamadığı anlaşılmış ve Pediatrik ARDS PARDS için ayrı uzlaşı raporları düzenlenmiştir. Bu derlemede PARDS tanı ve tedavisi hakkında,güncel bilgiler ışığında bahsedilecektir

Keywords

Pediyatrik akut solunum sıkıntısı sendromu, tanı, tedavi

Pediatric Acute Respiratory Distress Syndrome

Abstract

Acute Respiratory Distress Syndrome ARDS is a worldwi- de and important clinical situation with increased morbi- dity and mortality. Since the year 1967 when ARDS, which is characterized with diffuse pulmonary parenchymal damage and hypoxemia was first defined many research and consensus reports have been written which especially focused on adult type pulmonary distress. When risk fac- tors, etiology, pathophysiology, and relevant data were considered, it has been understood that it did not entirely included pediatric age group. Thus, different consensus reports were edited for pediatric ARDS PARDS . In this review, diagnosis and treatment strategies about PARDS will be discussed in the light of updated information

Keywords

Pediatric acute respiratory distress syndrome, diagnosis, treatment

References

• Ashbaugh DG, Bigelow DB, Petty Tl, et al. Acute respiratory distress in adults. Lancet 1967;2:319-32. https://doi.org/10.1016/S0140-6736(67)90168-7
• Brun-Buisson C, Minelli C, Bertolini G, et al. Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study. Intensive Care Med 2004;30:51-61. https://doi.org/10.1007/s00134-003-2136-x
• Rubenfeld GD, Caldwell E, Peabody E, et al. Incidence and outcomes of acute lung injury. N Engl J Med 2005;353:1685-93. https://doi.org/10.1056/NEJMoa050333
• Villar J, Blanco J, A-ón JM, et al. The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation. Intensive Care Med 2011;37:1932-41. https://doi.org/10.1007/s00134-011-2380-4
• Ranieri VM, Rubenfeld GD, Thompson BT, et al. Acute respiratory distress syndrome: the Berlin Definition. JAMA 2012;307:2526-33.
• Villar J, Blanco J, Kacmarek RM. Current incidence and outcome of the acute respiratory distress syndro- me. Curr Opin Crit Care 2016;22:1-6. https://doi.org/10.1097/MCC.0000000000000266
• Azevedo lC, Park M, Salluh JI, et al. Clinical outco- mes of patients requiring ventilatory support in Brazilian intensive care units: a multicenter, prospecti- ve, cohort study. Crit Care 2013;17:R63. https://doi.org/10.1186/cc12594
• Caser EB, Zandonade E, Pereira E, et al. Impact of distinct definitions of acute lung injury on its incidence and outcomes in Brazilian ICUs: prospective evaluati- on of 7,133 patients. Crit Care Med 2014;42:574-82. https://doi.org/10.1097/01.ccm.0000435676.68435.56
• Pediatric Acute lung Injury Consensus Conference Group. “Pediatric acute respiratory distress syndrome: consensus recommendations from the Pediatric Acute Lung Injury Consensus Conference.” Pediatric Critical Care Medicine 2015;16(5):428-39. https://doi.org/10.1097/PCC.0000000000000350
• Bernard GR, Artigas A, Brigham Kl, et al. The American-European Consensus Conference on ARDS. Definitions, Mechanisms, relevant outcomes, and clini- cal trial coordination. Am J Respir Crit Care Med 1994; 149:818-24. https://doi.org/10.1164/ajrccm.149.3.7509706
• Cho YJ, Moon JY, Shin ES, Kim JH, Jung H, et al; Korean Society of Critical Care Medicine, Korean Academy of Tuberculosis and Respiratory Diseases Consensus Group. Clinical Practice Guideline of Acute Respiratory Distress Syndrome. Tuberc Respir Dis (Seoul) 2016;79(4):214-33. https://doi.org/10.4046/trd.2016.79.4.214
• Ware lB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000;342:1334-49. https://doi.org/10.1056/NEJM200005043421806
• Wolthuis EK, Vlaar APJ, Choi G, Roelofs JJTH, Juff ermans NP, Schultz MJ. Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice. Crit Care 2009;13:R1. https://doi.org/10.1186/cc7688
• Plötz FB, Slutsky AS, Van Vught AJ, Heijnen CJ. Ventilator-induced lung injury and multiple system organ failure: a critical review of facts and hypotheses. Intensive Care Med 2004;30:1865-72. https://doi.org/10.1007/s00134-004-2363-9
• Villar J, Blanco J, Zhang H, Slutsky AS. Ventilator- induced lung injury and sepsis: two sides of the same coin? Minerva Anestesiol 2011;77:647-53.
• Bateman ST, Borasino S, Asaro lA, Cheifetz IM, Diane S, et al. Early high-frequency oscillatory venti- lation in pediatric acute respiratory failure: a propensity score analysis. Am J Respir Crit Care Med 2016;193(5):495-503. https://doi.org/10.1164/rccm.201507-1381OC
• Gebistorf F, Karam O, Wetterslev J, Afshari A. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults. Cochrane Database Syst Rev 2016;(6):CD002787. https://doi.org/10.1002/14651858.CD002787.pub3
• Amigoni A, Pettenazzo A, Stritoni V, Circelli M. Surfactants in Acute Respiratory Distress Syndrome in Infants and Children: Past, Present and Future. Clin Drug Investig 2017 May 16. https://doi.org/10.1007/s40261-017-0532-1
• Grams ME, Estrella MM, Coresh J, et al. Fluid balance, diuretic use, and mortality in acute kidney injury. Clin J Am Soc Nephrol 2011;6:966-73. https://doi.org/10.2215/CJN.08781010
• Wiedemann HP, Wheeler AP, Bernard GR, Thompson BT, Hayden D, deBoisblanc B, et al: National Heart Lung and Blood Institute Acute Respiratory Distress Syndrome ARDS Clinical Trials Network; Comparison of two fluid-management strate- gies in acute lung injury. N Engl J Med 2006;354:2564- 75.
• Adnet F, Dhissi G, Borron SW, Galinski M, Rayeh F, Cupa M, Pourriat Jl, et al. Complication profi les of adult asthmatics requiring paralysis during mechani- cal ventilation. Intensive Care Med 2001;27:1729-36. https://doi.org/10.1007/s00134-001-1112-6
• Hartmann SM, Hough Cl. Argument against the Routine Use of Steroids for Pediatric Acute Respiratory Distress Syndrome. Front Pediatr 2016;4:79. https://doi.org/10.3389/fped.2016.00079