PFAPA Sendromunda Prokalsitonin Düzeyleri

Year 2017, , 122 - 126, 01.07.2017

Nalan Karabayır Serdar Al , Tijen Alkan Bozkaya Ali Demirhan Meliha Aksoy Okan

https://doi.org/10.5222/j.child.2017.122

Abstract

Amaç: PFAPA sendromu tanısı konan çocuklarda febril atak sırasında prokalsitonin PCT düzeylerinin araştırılması. Gereç ve Yöntem: Çalışmaya 91 ateşli atak geçiren toplam 39 vaka ile bakteriyel septisemi tanısı konan 35 vaka kontrol grubu olarak alındı. Demografik, klinik ve laboratuvar bulguları kaydedildi. Her iki grupta hemogram, CRP ve PCT değerleri araştırıldı. Bulgular: Çalışma grubunda atak süresi ort 4,6 ±0,45 gün olup atak sıklıkları arasındaki süre ort 25,06±9,76 gün olarak saptandı. Çalışma grubunda ortalama lökosit, CRP and PCT değerleri sırasıyla 15,959±5,737/mm3, 76,88±47,63 mg/L ve 0,18±0,10 ng/mL bulundu. PFAPA sendromlu hastalarda boğaz kültürlerinde üreme saptanmadı. Kontrol grubundaki vakaların 20’si kız, 15’i erkekti. Ortalama lökosit sayısı 16,700±5,820/mm3 saptanırken, CRP değeri ise 34,64±18,61 mg/L, PCT düzeyi 2,12±1,95 ng/mL ölçüldü. Lökosit değerleri açısından iki grup arasında fark bulunamazken p>0,05 , PCT değerleri kontrol grubunda anlamlı düzeyde yüksekti p

Keywords

Ateş, CRP, PFAPA, prokalsitonin

Procalcitonin Levels in PFAPA Syndrome

Abstract

Objective: To investigate procalcitonin PCT levels during febrile attacks in children diagnosed with the Periodic Fever, Aphthous Stomatitis, Pharyngitis, Adenitis Syndrome PFAPA . Material and Method: A total of 39 cases with 91 febril episodes and 35 cases with bacterial septicemia were included in the study. Demographic, clinical, and laboratory data were collected. Hemogram, C-reactive values CRP and PCT values of all patients were measured. Results: In the study group with PFAPA, average duration of fever was 4.6±0.85 days, and the average time between attacks was 25.06±9.76 days. The mean white blood cell WBC , CRP and PCT values were found to be 15.959±5.737/mm3, 76.88±47.63 mg/L, and 0.18±0.10 ng/mL respectively. Throat cultures in the PFAPA group showed no growth. Twenty patients in the control group were female and 15 were male. The average WBC count was 16.700±5.820/mm3. The mean CRP and PCT values were measured as 34.64±18.2 mg/L and 2.12±1.95 ng/mL, respectively. While the mean WBC values did not significantly differ between the two groups p>0.05 , PCT levels were significantly higher in the controls compared to the PFAPA group p

Keywords

C-reactive protein, fever, PFAPA, procalcitonin

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