Astımlı Bir Vakada Yineleyen Influenza Enfeksiyonu

Abstract

Influenza viral enfeksiyonlar arasında en sık gözlenenler- den birisidir. Mevsimsel influenza olarak adlandırılan bu enfeksiyon özellikle 2 yaşın altındaki çocuklarda, 65 yaşın üzerindeki kişilerde ve altta yatan astım gibi kronik hasta- lığı bulunanlarda yüksek oranda atak hızına, komplikas- yonlara ve ölüm oranlarına neden olur. Influenza enfeksi- yonunun toplumda yayılımı ve bulaşıcılığının önemli kay- nağı çocuklardır ve en önemli koruyucu tedavi de aşıdır. Burada, mevsimsel influenza aşısına rağmen, 3 kez influen- za enfeksiyonu geçirmiş 15 yaşında astımlı bir erkek hasta sunulmuştur

Keywords

• Astım,aşı,influenza

Rekurren Influenza Infections in an Asthmatic Child

Abstract

Influenza is one of the most common viral infections. This infection called as seasonal influenza is mostly seen in children under 2 years of age, adults older than 65 years, and patients who have underlying chronic diseases such as asthma. In these risky groups, it leads to increased attack rates, complications and death rates. The most important source of the spread of influenza infection in the commun- mity is children and the most important prophylactic treat- ment is vaccination. In this paper, 15-year-old boy with chronic asthma who had 3 times experienced influenza infection, though he had received seasonal vaccination

Keywords

• Asthma,vaccine,influenza

References

1. nicholson kG, Wood Jm, zambon m. Influenza. Lancet 2003;362:1733-45. https://doi.org/10.1016/S0140-6736(03)14854-4
2. Cohen Gm, nettleman mD. Economic impact of influenza vaccination in preschool children. Pediatrics 2000;106:973-6. https://doi.org/10.1542/peds.106.5.973
3. monto AS, Davenport Fm, napier JA, Francis T Jr. Effect of vacci- nation of a school-age population upon the course of an A2-Hong Kong influenza epidemic. Bull World Health Organ 1969;41:537-42.
4. reichert TA, Sugaya n, Fedson DS, Glezen WP, Simonsen l, Tashiro m. The Japanese experience with vaccinating school children against influenza. N Engl J Med 2001;344:889-96. https://doi.org/10.1056/NEJM200103223441204
5. Centers for Disease Control (CDC). Prevention and control of influenza. MMWR Morb Mortal Wkly Rep 1984;33:253-60.
6. Crawford nW, Bines JE, royle J, Buttery JP. Optimizing immunization in pediatric special risk gro- ups. Expert Rev Vaccines 2011;10:175-86. https://doi.org/10.1586/erv.10.157
7. ruben Fl. Inactivated influenza virus vaccines in children. Clin Infect Dis 2004;38:678-88. https://doi.org/10.1086/382883
8. Dayan GH, nguyen VH, Debbag r, Gomez r, Wood SC. Cost-effectiveness of influenza vaccination in high-risk children in Argentina. Vaccine 2001;19:4204- 13. https://doi.org/10.1016/S0264-410X(01)00160-8

9. Sugaya n, nerome k, Ishida m, matsumoto m, mitamura k, nirasawa m. Efficacy of inactivated vaccine in preventing antigenically drifted influenza type A andwell-matchedtype B. JAMA 1994; 272: 1122-6. https://doi.org/10.1001/jama.1994.03520140052037
10. Thesafety of inactivated influenza vaccine in adults and children with asthma. N Engl J Med 2001;345:1529- 36.
11. Halperin SA, Smith B, mabrouk T, Germain m, Trepanier P, Hassell T, et al. Safety and immunogeni- city of a trivalent, inactivated, mam- maliancell culture- derived influenza vaccine in healthy adults, seniors, and children. Vaccine 2002;20:1240-7. https://doi.org/10.1016/S0264-410X(01)00428-5
12. Pedroza A, Huerta JG, Garcia mde l, rojas A, lopez-martinez I, Penagos m, et al. The safety and immunogenicity of influenza vaccine in children with asthma in Mexico. Int J Infect Dis 2009;13:469-75. https://doi.org/10.1016/j.ijid.2008.08.015
13. Hanania nA, Sockrider m, Castro m, Holbrook JT, Tonascia J, Wise r, et al. Immune response to influ- enza vaccination in children and adults with asthma: effect of corticosteroid therapy. J Allergy Clin Immunol 2004;113:717-24. https://doi.org/10.1016/j.jaci.2003.12.584
14. Bueving HJ, Bernsen rm, de Jongste JC, van Suijlekom-Smit lW, rimmelzwaan GF, osterhaus AD, et al. Influenza vaccination in children with ast- hma: randomize double-blind placebo-controlled trial. Am J Respir Crit Care Med 2004;169:488-93. https://doi.org/10.1164/rccm.200309-1251OC
15. longini Im Jr, Halloran mE. Strategy for distributi- on of influenza vaccine to high-risk groups and child- ren. Am J Epidemiol 2005;161:303-6. https://doi.org/10.1093/aje/kwi053
16. Cates CJ, et al. Vaccines for preventing influenza in people with asthma. Cochrane Database Syst Rev. (2013)
17. Bae EY, Choi UY, kwon HJ, Jeong DC, rhim JW, ma SH, et al. Immunogenicity and safety of an inacti- vated trivalent split influenza virus vaccine in young children with recurrent wheezing. Clin Vaccine Immunol 2013;20:811-7. https://doi.org/10.1128/CVI.00008-13