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Çocukların Kuru Tozlu İnhalerleri Kullanma Yetileri

Year 2015, , 74 - 77, 01.04.2015
https://doi.org/10.5222/j.child.2015.074

Abstract

Amaç: İnhalerlerin çalıştırılmasıyla inhalasyon arasında koordinasyona gerek olmadığı ve cihazlar kolayca taşındığı için kuru tozlu inhalerler KTİ’ler giderek artan sıklıkta kullanılmaktadırGereç ve Yöntemler: Bu çalışmanın amacı, 6-8 yaş arası 20 astım hastası 5 kız ve 15 erkek çocuk ve ve 39 sağlıklı okul çocuğunda 15 kız ve 24 erkek çocuk tepe inspiratuar akım hızının TİAH ölçümüyle bu yaş grubunda KTİ’lerin uygulanabilirliğini değerlendirmekti. Çalışmaya hafif-orta derecede astımı olanlar alınmıştır. TİA’ların ölçümleri In-Check Dial Clement Clarke International, UK cihazıyla değerlendirilmiştir. FEV1 ve PEF’yi de içeren akciğer fonksiyon testleri gerçekleştirilmiştir.Bulgular: Astımlı grup için ortanca FEV1, PEF ve PIF ve yüzdeleri sırasıyla 91.6, %28,5; 82.4, %21.1 ve 78.8, 26.4 L/dk. idi. Sağlıklı kontroller için karşıt ölçümler sırasıyla 89,5, %14.7, 81.7 %16.0 ve 81.2 2, 0.2 L/dk. idi. PIF aralıkları astımlılar için 40 L/dk. 120 L/dk., sağlıklı kontroller için 45 120 L/dk. idi. Her iki grupta PIF ie FEV1 arasında pozitif bir korelasyon gözlenmiştir p

References

  • Global Strategy for Asthma Management and Prevention (Revised 2014) www.ginasthma.org.
  • Grossman J. Thee volution of inhaler technology. J Asthma 1994;31:55-64. http://dx.doi.org/10.3109/02770909409056770
  • Anderson PJ. Delivery options and devices for aero- solized therapeutics. Chest 2000;120(3):89-93. http://dx.doi.org/10.1378/chest.120.3_suppl.89S
  • Parry-Billings m, Birrell c, oldham l, o’callaghan c. Inspiratory flow rate through dry powder inhaler (Clickhaler) in children with asthma. Pediatr Pulmonol 2003;35:220-6. http://dx.doi.org/10.1002/ppul.10234
  • Srichana t, martin GP, marriott c. Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro. Eur J Pharm Sci 1998;7:73-80. http://dx.doi.org/10.1016/S0928-0987(98)00008-6
  • dolovich m. Aerosol delivery to children: what to use, how to choose. Pediatr Pulmonol 1999;18:79-82. http://dx.doi.org/10.1002/(SICI)1099-0496(1999)27: 18+3.0.CO;2-9
  • Agertoft l, Pedersen S. Importance of training for correct turbuhaler use in preschool children. Acta Paediatr 1998;87:842-7. http://dx.doi.org/10.1111/j.1651-2227.1998.tb01548.x
  • o’callaghan c, everard ml, Bush A, Hiller eJ, ross-russell r, o’keefe P, et al. Salbutamol dry powder inhaler: efficacy, tolerability, and acceptability study. Pediatr Pulmonol 2002;33:189-93. http://dx.doi.org/10.1002/ppul.10048
  • nielsen kG, Skov m, klug B, Ifversen m, Bisgaard H. Flow dependent effect of formoterol dry-powder from the Aerolizer (RM). Eur Respir J 1997;10: 2105-9. http://dx.doi.org/10.1183/09031936.97.10092105
  • Garcia-marcos Alvarez l, martinez tA, Guillen PJJ, martinez Victoria A. Peak inspiratory flow using 2 different inhalers and a new portable device. An Esp Pediatr 2001;5482:110-3.
  • Aguilar miranda P, mallol Villablanca J. Maximum inspiratory flows in healthy children and asthmatics 4 to 8 years old. The implications for the inhalation of drugs in powder form. Arch Bronconeumol 2000; 36(2):73-6. http://dx.doi.org/10.1016/S0300-2896(15)30211-8
  • nantel nP, newhouse mt. Inspiratory flow rates through a novel dry powder inhaler (Clickhaler) in pediatric patients with asthma. J Aerosol Med 1999; 12(2):55-8. http://dx.doi.org/10.1089/jam.1999.12.55
  • de Boeck k, Alifier m, Warnier G. Is the correct use of a dry powder inhaler (Turbohaler) age dependent? J Allergy Clin Immunol 1999;103:763-6. http://dx.doi.org/10.1016/S0091-6749(99)70417-3
  • engel t, Heinig JH, madsen F, nikander k. Peak inspiratory flow and inspiratory vital capacity of patients with asthma measured with and without a new dry-powder inhaler device (Turbuhaler). Eur Respir J 1990; 3(9):1037-41.
  • drblik S, lapierre G, thivierge r, turgeon J, Gaudreault P, cummunis-mcmanus B, et al. Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurized metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode. Arch Dis Child 2003;88(4):319-23. http://dx.doi.org/10.1136/adc.88.4.319

The Ability of Children to Use Dry Powder Inhalers

Year 2015, , 74 - 77, 01.04.2015
https://doi.org/10.5222/j.child.2015.074

Abstract

Objective: Dry powder inhalers DPIs are used in children with increased frequency, since no coordination between actuation and inhalation is required and the devices can easily be carried around.Material and Methods: The aim of this study was to measure the peak inspiratory flow PIF in 20 asthmatic 5F, 15M and 39 15 F, 24 M healthy school children aged 6 to 8 years, and to evaluate the applicability of DPI in this age group. Children with mild to moderate asthma were included in the study. PIF was performed by means of In-Check Dial Clement Clarke International, UK . Pulmonary function tests including FEV1 and PEF were performed. Results: For the asthmatic group median FEV1, PEF and PIF and related percentages were 91.6 28.5% , 82.4 21.1% and 78.8 26.4 L/min, respectively. For the healthy controls, the respective measurements were 89.5 14.7% , 81.7 16.0% and 81.2 20.2 L/min. Ranges for the asthmatics were 40 L/min to 120 L/min, and 45 to 120 for the healthy controls A positive correlation between PIF and FEV1 p

References

  • Global Strategy for Asthma Management and Prevention (Revised 2014) www.ginasthma.org.
  • Grossman J. Thee volution of inhaler technology. J Asthma 1994;31:55-64. http://dx.doi.org/10.3109/02770909409056770
  • Anderson PJ. Delivery options and devices for aero- solized therapeutics. Chest 2000;120(3):89-93. http://dx.doi.org/10.1378/chest.120.3_suppl.89S
  • Parry-Billings m, Birrell c, oldham l, o’callaghan c. Inspiratory flow rate through dry powder inhaler (Clickhaler) in children with asthma. Pediatr Pulmonol 2003;35:220-6. http://dx.doi.org/10.1002/ppul.10234
  • Srichana t, martin GP, marriott c. Dry powder inhalers: The influence of device resistance and powder formulation on drug and lactose deposition in vitro. Eur J Pharm Sci 1998;7:73-80. http://dx.doi.org/10.1016/S0928-0987(98)00008-6
  • dolovich m. Aerosol delivery to children: what to use, how to choose. Pediatr Pulmonol 1999;18:79-82. http://dx.doi.org/10.1002/(SICI)1099-0496(1999)27: 18+3.0.CO;2-9
  • Agertoft l, Pedersen S. Importance of training for correct turbuhaler use in preschool children. Acta Paediatr 1998;87:842-7. http://dx.doi.org/10.1111/j.1651-2227.1998.tb01548.x
  • o’callaghan c, everard ml, Bush A, Hiller eJ, ross-russell r, o’keefe P, et al. Salbutamol dry powder inhaler: efficacy, tolerability, and acceptability study. Pediatr Pulmonol 2002;33:189-93. http://dx.doi.org/10.1002/ppul.10048
  • nielsen kG, Skov m, klug B, Ifversen m, Bisgaard H. Flow dependent effect of formoterol dry-powder from the Aerolizer (RM). Eur Respir J 1997;10: 2105-9. http://dx.doi.org/10.1183/09031936.97.10092105
  • Garcia-marcos Alvarez l, martinez tA, Guillen PJJ, martinez Victoria A. Peak inspiratory flow using 2 different inhalers and a new portable device. An Esp Pediatr 2001;5482:110-3.
  • Aguilar miranda P, mallol Villablanca J. Maximum inspiratory flows in healthy children and asthmatics 4 to 8 years old. The implications for the inhalation of drugs in powder form. Arch Bronconeumol 2000; 36(2):73-6. http://dx.doi.org/10.1016/S0300-2896(15)30211-8
  • nantel nP, newhouse mt. Inspiratory flow rates through a novel dry powder inhaler (Clickhaler) in pediatric patients with asthma. J Aerosol Med 1999; 12(2):55-8. http://dx.doi.org/10.1089/jam.1999.12.55
  • de Boeck k, Alifier m, Warnier G. Is the correct use of a dry powder inhaler (Turbohaler) age dependent? J Allergy Clin Immunol 1999;103:763-6. http://dx.doi.org/10.1016/S0091-6749(99)70417-3
  • engel t, Heinig JH, madsen F, nikander k. Peak inspiratory flow and inspiratory vital capacity of patients with asthma measured with and without a new dry-powder inhaler device (Turbuhaler). Eur Respir J 1990; 3(9):1037-41.
  • drblik S, lapierre G, thivierge r, turgeon J, Gaudreault P, cummunis-mcmanus B, et al. Comparative efficacy of terbutaline sulphate delivered by Turbuhaler dry powder inhaler or pressurized metered dose inhaler with Nebuhaler spacer in children during an acute asthmatic episode. Arch Dis Child 2003;88(4):319-23. http://dx.doi.org/10.1136/adc.88.4.319
There are 15 citations in total.

Details

Primary Language English
Journal Section Research Articles
Authors

Zeynep Tamay This is me

Deniz Özçeker This is me

Nermin Güler This is me

Ülker Öneş This is me

Publication Date April 1, 2015
Published in Issue Year 2015

Cite

APA Tamay, Z., Özçeker, D., Güler, N., Öneş, Ü. (2015). The Ability of Children to Use Dry Powder Inhalers. Çocuk Dergisi, 15(2), 74-77. https://doi.org/10.5222/j.child.2015.074
AMA Tamay Z, Özçeker D, Güler N, Öneş Ü. The Ability of Children to Use Dry Powder Inhalers. Çocuk Dergisi. April 2015;15(2):74-77. doi:10.5222/j.child.2015.074
Chicago Tamay, Zeynep, Deniz Özçeker, Nermin Güler, and Ülker Öneş. “The Ability of Children to Use Dry Powder Inhalers”. Çocuk Dergisi 15, no. 2 (April 2015): 74-77. https://doi.org/10.5222/j.child.2015.074.
EndNote Tamay Z, Özçeker D, Güler N, Öneş Ü (April 1, 2015) The Ability of Children to Use Dry Powder Inhalers. Çocuk Dergisi 15 2 74–77.
IEEE Z. Tamay, D. Özçeker, N. Güler, and Ü. Öneş, “The Ability of Children to Use Dry Powder Inhalers”, Çocuk Dergisi, vol. 15, no. 2, pp. 74–77, 2015, doi: 10.5222/j.child.2015.074.
ISNAD Tamay, Zeynep et al. “The Ability of Children to Use Dry Powder Inhalers”. Çocuk Dergisi 15/2 (April 2015), 74-77. https://doi.org/10.5222/j.child.2015.074.
JAMA Tamay Z, Özçeker D, Güler N, Öneş Ü. The Ability of Children to Use Dry Powder Inhalers. Çocuk Dergisi. 2015;15:74–77.
MLA Tamay, Zeynep et al. “The Ability of Children to Use Dry Powder Inhalers”. Çocuk Dergisi, vol. 15, no. 2, 2015, pp. 74-77, doi:10.5222/j.child.2015.074.
Vancouver Tamay Z, Özçeker D, Güler N, Öneş Ü. The Ability of Children to Use Dry Powder Inhalers. Çocuk Dergisi. 2015;15(2):74-7.