Obez Çocuklarda Metabolik Sendrom Sıklığı ve Bileşenlerinin Değerlendirilmesi

Abstract

Amaç: Bu çalışmanın amacı obez çocuklarda metabolik sendrom ve bileşenlerinin ne sıklıkta olduğunu ortaya koymaktır. Gereç ve Yöntem: Bu çalışmaya Ocak 2013-Aralık 2014 tarihleri arasında Gaziosmanpaşa Üniversitesi Tıp Fakültesi Çocuk Sağlığı ve Hastalıkları Polikliniğine başvuran obez çocuklar dâhil edilmiştir. Beden kitle indeksi BKİ yaşa ve cinsiyete göre > 95p olan hastalar obezite tanısı aldı. Bu çalışmaya kliniğimizde takip edilen 372 hasta dâhil edilmiştir ve hastaların yaşları 10-17 arasında değişmektedir. Tüm hastaların antropometrik ölçümleri, beden kitle indeksleri, kan basıncı değerleri, açlık insülin düzeyleri, total kolesterol, HDL kolesterol ve trigliserid verileri hastane kayıtlarından elde edilmiştir. Tüm hastalarda insülin direnci varlığı homeostatic model assessmentinsulin resistance HOMA-IR yöntemi ile hesaplanmıştır. Aterojenik indeks log TG/HDL-C formülü ile hesaplandı. Hastalara metabolik sendrom tanısı çocuklar için modifiye edilmiş WHO kriterlerine göre konmuştur.Bulgular: Obez çocuklarda metabolik sendrom %22.04 n: 82 , dislipidemi %38.98 n: 145 , hipertansiyon %16.40 n: 61 ve insülin direnci %55.12 n: 205 sıklığında görülmüştür. Cinsiyetlere göre ayrıldığında metabolik sendrom bileşenleri arasında insülin rezistansı dışında istatistiki anlamlı farklılık görülmemiştir. Ancak, prepubertal çocuklarda kan basıncı düzeyleri daha düşük ve insülin direnci ortalamaları daha düşük saptanırken, HDL düzeyleri de anlamlı şekilde daha yüksek saptandı p

Keywords

• Obezite,insülin rezistansı,metabolik sendrom

Evaluation of Frequency of Metabolic Syndrome and its Components in Obese Children

Abstract

Objective: The aim of this study is to reveal the frequency of metabolic syndrome and its components in obese children. Material and Method: This study was conducted in Gaziosmanpasa University School of Medicine Department of Children’s Health and Diseases between January 2013 and December 2014. Study population included only obese children. The patients with age, and gender -adjusted body mass indices BMIs over 95 p were assigned the diagnosis of obesity.A total of 372 patients who had been followed up in our clinic were enrolled in the study. The ages of the patients ranged between 10 and 17 years. Patients’ data on anthropometric measurements, body mass indices, blood pressure, fasting insulin, total cholesterol, HDL cholesterol and triglyceride values were obtained from hospital records. In all patients, the presence of insulin resistance was calculated by homeostatic model assessment-insulin resistance HOMA- IR method. Atherogenic index was calculated with the formula log TG/HDL-C . All children were diagnosed with metabolic syndrome based on WHO criteria modified for children.Results: Metabolic syndrome, dyslipidemia, hypertension, and insulin resistance were seen in 22.04% n: 82 , 38.98% n: 145 , 16.40% n: 61 and 55.12% n: 205 of the obese children, respectively. A statistically significant difference was not found between genders in terms of the components of metabolic syndrome except insulin resistance. However, blood pressure levels and mean insulin resistance values were lower in prepubertal children, while HDL levels were found to be significantly higher p

Keywords

• Obesity,insulin resistance,metabolic syndrome

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