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Çocuklarda Obezitenin Astıma Etkisi

Year 2014, , 72 - 77, 01.04.2014
https://doi.org/10.5222/j.child.2014.072

Abstract

Amaç: Astım ve obezite sıklığı son yıllarda artmaktadır. Obezite astım açısından bir risk faktörüdür. Astımlı hastalarda obezite varlığı hastalığı klinik seyrini etkileyebilmektedir. Astım tanısı olan hastalarda obezitenin astımın klinik seyri ve solunum fonksiyon testleri üzerine etkisini saptamak amacıyla bu çalışma yapılmıştır. Gereç ve Yöntem: Çalışmaya Çocuk İmmünolojisi ve Allerji Polikliniğinde astım tanısı ile takip edilen 160 çocuk 18 yaş altı hasta alındı. Hastalar Ocak 2011 - Haziran 2011 arasında prospektif olarak değerlendirildi. Hastaların ayrıntılı allerjik hastalık öyküsü, yaş, akraba evliliği, ailede atopi öyküsü, sigara dumanına maruziyet, son 1 yıldaki atak sayısı ve sistemik steroid alma sıklığı sorgulandı. Astım kontrol testi solunum fonksiyon testleri, deri prick testleri, eozinofili ve total immunglobulin E ölçümü yapıldı. Bel çevresi 90.p’in üstündeki hastalar obez olarak kabul edildi. Bulgular: Hastaların 96’sı %60 normal kilolu, 64’ü %40 obez idi. İki grup arasında yaş, cinsiyet, akraba evliliği, ailede atopi öyküsü, sigara, atopi açısından anlamlı farklılık bulunmadı. Obez olan astımlıların son 1 yıldaki atak sayıları ve sistemik steroid gereksinimleri, normal kilolulara göre anlamlı olarak fazlaydı p

References

  • camargo cA Jr, Weiss st, zhang s, Willett Wc, speizer FE. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med ;159:2582-8. http://dx.doi.org/10.1001/archinte.159.21.2582 dent asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007;175:661-6. http://dx.doi.org/10.1164/rccm.200611-1717OC
  • Peled r, et al. The relationship between asthma and obesity in children: is it real or a case of over diagnosis? J Asthma ;41:403-10. http://dx.doi.org/10.1081/JAS-120026097 sal relationship? A systematic review. Respir Med ;107(9):1287-300. http://dx.doi.org/10.1016/j.rmed.2013.03.019
  • Maldonado M, et al. Obesity and its relationship with asthma prevalence and severity in adolescents from southern Brazil. J Asthma 2006;43:57-60. http://dx.doi.org/10.1080/02770900500448597 ween asthma severity and obesity. J Asthma 2004;41: 521-6. http://dx.doi.org/10.1081/JAS-120037651 ratio is a rapid and effective global indicator for health risks of obesity and how its use could simplify the international public health message on obesity. Int J Food Sci Nutr 2005;56(5): 7. http://dx.doi.org/10.1080/09637480500195066
  • M. Secular changes in body fat patterning in children and adolescents of Zaragoza (Spain), 1980-1995. Int J Obes Relat Metab Disord 2001;25(11):1656-60. http://dx.doi.org/10.1038/sj.ijo.0801803
  • NS, et al. Waist circumference is a better predictor than body mass index of coronary heart disease risk in overweight pre- menopausal women. J Nutr 2004;134(5):1071-6.
  • Mosen DM, schatz M, Magid DJ, camargo cA Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008;122(3):507-11. http://dx.doi.org/10.1016/j.jaci.2008.06.024
  • N, et al. Abdominal Obesity and respiratory function in men and women in the EPIC-Norfolk Study, United Kingdom. Am J Epidemiol 2004;159(12):1140-9. http://dx.doi.org/10.1093/aje/kwh155 asthma: a specific phenotype? Chest 2008;134(2):317-23. http://dx.doi.org/10.1378/chest.07-2959
  • Husemoen ll, Aadahl M, et al. Exploring the obesity- asthma link: do all types of adiposity increase the risk of ast- hma? Clin Exp Allergy 2012;42(8):1237-45. http://dx.doi.org/10.1111/j.1365-2222.2012.03972.x
  • Bilderback A, riekert KA, et al. Does higher body mass index contribute to worse asthma control in an urban popula- tion? J Allergy Clin Immunol 2009;124(2):207-12. http://dx.doi.org/10.1016/j.jaci.2009.05.034
  • V, Picado C. Increased body mass index does not lead to a worsening of asthma control in a large adult asthmatic popu- lation in Spain. J Investig Allergol Clin Immunol 2010;20(7): 5.
  • K, succop P, et al. Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant. J Allergy Clin Immunol 2009;123(6):1321-7. http://dx.doi.org/10.1016/j.jaci.2009.03.023
  • JM, FitzGerald M, et al. Global strategy for asthma manage- ment and prevention: GINA executive summary. Eur Respir J ;31(1):143-78. http://dx.doi.org/10.1183/09031936.00138707 and interpretative strategies. Am Rev Respir Dis 1991;144(5): 18. http://dx.doi.org/10.1164/ajrccm/144.5.1202
  • Darendeliler F ve ark. Türk çocuklarında vücut ağırlığı, boy uzunluğu, baş çevresi ve vücut kitle indeksi referans değerleri Çocuk Sağlığı ve Hastalıkları Dergisi 2008;51:1-14.
  • Seyhan S, et al. Waist circumference percentiles for 7- to year-old Turkish children and adolescents. Eur J Pediatr ;167(4):383-9. http://dx.doi.org/10.1007/s00431-007-0502-3
  • DJ, O’connor E, et al. The relationship between asthma- specific quality of life and asthma control. J Asthma 2007; (5):391-5. http://dx.doi.org/10.1080/02770900701364296
  • Golshan M. Association between asthma and body mass index in children. Iran J Allergy Asthma Immunol 2005;4: 7.
  • Galbreath AD. Impact of obesity in asthma: evidence from a large prospective disease management study. An Allergy Asthma Immunol 2011;106:30-5. http://dx.doi.org/10.1016/j.anai.2010.10.015
  • Higher VKİ is associated with worse asthma control and qua- lity of life but not asthma severity. Respir Med 2006;100(4): 7. http://dx.doi.org/10.1016/j.rmed.2005.08.001 rence is associated with Pulmonary function in normal-weight, overweight, and obese subjects. Am J Clin Nutr 2007;85(1): 9. al. Childhood Asthma Management Program Research Group.
  • Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax ;58(12):1036-41. http://dx.doi.org/10.1136/thorax.58.12.1036
  • Arvanitidou V, Emporiadou M, et al. The effect of obesity on pulmonary lung function of school aged children in Greece. Pediatr Pulmonol 2009;44:273-80. http://dx.doi.org/10.1002/ppul.20995 ve ark. The effect of childhood obesity on respiratory functi- on tests and airway hyperresponsiveness. The Turkish Journal of Pediatrics 2006;48:43-50. adipokines and hormones of obesity in childhood asthma.
  • Allergy Asthma Immunol Res 2012;4(2):98-103. http://dx.doi.org/10.4168/aair.2012.4.2.98
  • Balducci Mt, Petruzzelli l, et al. Obesity can influence children’s and adolescents’ airway hyperresponsiveness diffe- rently. Multidiscip Respir Med 2013;12:8(1):60.

The Effect of Obesity on Asthma in Children

Year 2014, , 72 - 77, 01.04.2014
https://doi.org/10.5222/j.child.2014.072

Abstract

Introduction: The prevalence of obesity and asthma is increasing in recent years. Obesity is a risk factor for asthma. The presence of obesity may affect the clinical course of the disease in patients with asthma. This study was conducted to determine the effect of obesity on clinical course of asthma and pulmonary function tests in children with asthma. Material and Method: One hundred and sixty children with asthma who were followed in Pediatric ImmunologyAllergy Clinic were included in this study. Patients were evaluated prospectively between January 2011-June 2011. The patients were interrogated with detailed history of allergic disease, age, kin marriage, familial atopy, exposure to tobacco smoke, number of asthma attacks within the previous year, and systemic steroid use. Asthma control test, pulmonary function tests, skin prick tests, eosinophilia and total immunoglobulin E measurements were performed. Patients with waist circumferences above the 90th percentile were considered obese. Results: Ninety-six 60% patients were of normal weight and 64 40% of them were obese. There were no statistically significant difference between both groups in terms of age, gender, consanguinity, family history of atopy, smoking, and atopy. The number of attacks and need of systemic steroid within the previous one year were significantly higher in obese asthmatics compared to normalweight individuals p

References

  • camargo cA Jr, Weiss st, zhang s, Willett Wc, speizer FE. Prospective study of body mass index, weight change, and risk of adult-onset asthma in women. Arch Intern Med ;159:2582-8. http://dx.doi.org/10.1001/archinte.159.21.2582 dent asthma: a meta-analysis of prospective epidemiologic studies. Am J Respir Crit Care Med 2007;175:661-6. http://dx.doi.org/10.1164/rccm.200611-1717OC
  • Peled r, et al. The relationship between asthma and obesity in children: is it real or a case of over diagnosis? J Asthma ;41:403-10. http://dx.doi.org/10.1081/JAS-120026097 sal relationship? A systematic review. Respir Med ;107(9):1287-300. http://dx.doi.org/10.1016/j.rmed.2013.03.019
  • Maldonado M, et al. Obesity and its relationship with asthma prevalence and severity in adolescents from southern Brazil. J Asthma 2006;43:57-60. http://dx.doi.org/10.1080/02770900500448597 ween asthma severity and obesity. J Asthma 2004;41: 521-6. http://dx.doi.org/10.1081/JAS-120037651 ratio is a rapid and effective global indicator for health risks of obesity and how its use could simplify the international public health message on obesity. Int J Food Sci Nutr 2005;56(5): 7. http://dx.doi.org/10.1080/09637480500195066
  • M. Secular changes in body fat patterning in children and adolescents of Zaragoza (Spain), 1980-1995. Int J Obes Relat Metab Disord 2001;25(11):1656-60. http://dx.doi.org/10.1038/sj.ijo.0801803
  • NS, et al. Waist circumference is a better predictor than body mass index of coronary heart disease risk in overweight pre- menopausal women. J Nutr 2004;134(5):1071-6.
  • Mosen DM, schatz M, Magid DJ, camargo cA Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008;122(3):507-11. http://dx.doi.org/10.1016/j.jaci.2008.06.024
  • N, et al. Abdominal Obesity and respiratory function in men and women in the EPIC-Norfolk Study, United Kingdom. Am J Epidemiol 2004;159(12):1140-9. http://dx.doi.org/10.1093/aje/kwh155 asthma: a specific phenotype? Chest 2008;134(2):317-23. http://dx.doi.org/10.1378/chest.07-2959
  • Husemoen ll, Aadahl M, et al. Exploring the obesity- asthma link: do all types of adiposity increase the risk of ast- hma? Clin Exp Allergy 2012;42(8):1237-45. http://dx.doi.org/10.1111/j.1365-2222.2012.03972.x
  • Bilderback A, riekert KA, et al. Does higher body mass index contribute to worse asthma control in an urban popula- tion? J Allergy Clin Immunol 2009;124(2):207-12. http://dx.doi.org/10.1016/j.jaci.2009.05.034
  • V, Picado C. Increased body mass index does not lead to a worsening of asthma control in a large adult asthmatic popu- lation in Spain. J Investig Allergol Clin Immunol 2010;20(7): 5.
  • K, succop P, et al. Comparison of anthropometric measures of obesity in childhood allergic asthma: central obesity is most relevant. J Allergy Clin Immunol 2009;123(6):1321-7. http://dx.doi.org/10.1016/j.jaci.2009.03.023
  • JM, FitzGerald M, et al. Global strategy for asthma manage- ment and prevention: GINA executive summary. Eur Respir J ;31(1):143-78. http://dx.doi.org/10.1183/09031936.00138707 and interpretative strategies. Am Rev Respir Dis 1991;144(5): 18. http://dx.doi.org/10.1164/ajrccm/144.5.1202
  • Darendeliler F ve ark. Türk çocuklarında vücut ağırlığı, boy uzunluğu, baş çevresi ve vücut kitle indeksi referans değerleri Çocuk Sağlığı ve Hastalıkları Dergisi 2008;51:1-14.
  • Seyhan S, et al. Waist circumference percentiles for 7- to year-old Turkish children and adolescents. Eur J Pediatr ;167(4):383-9. http://dx.doi.org/10.1007/s00431-007-0502-3
  • DJ, O’connor E, et al. The relationship between asthma- specific quality of life and asthma control. J Asthma 2007; (5):391-5. http://dx.doi.org/10.1080/02770900701364296
  • Golshan M. Association between asthma and body mass index in children. Iran J Allergy Asthma Immunol 2005;4: 7.
  • Galbreath AD. Impact of obesity in asthma: evidence from a large prospective disease management study. An Allergy Asthma Immunol 2011;106:30-5. http://dx.doi.org/10.1016/j.anai.2010.10.015
  • Higher VKİ is associated with worse asthma control and qua- lity of life but not asthma severity. Respir Med 2006;100(4): 7. http://dx.doi.org/10.1016/j.rmed.2005.08.001 rence is associated with Pulmonary function in normal-weight, overweight, and obese subjects. Am J Clin Nutr 2007;85(1): 9. al. Childhood Asthma Management Program Research Group.
  • Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP). Thorax ;58(12):1036-41. http://dx.doi.org/10.1136/thorax.58.12.1036
  • Arvanitidou V, Emporiadou M, et al. The effect of obesity on pulmonary lung function of school aged children in Greece. Pediatr Pulmonol 2009;44:273-80. http://dx.doi.org/10.1002/ppul.20995 ve ark. The effect of childhood obesity on respiratory functi- on tests and airway hyperresponsiveness. The Turkish Journal of Pediatrics 2006;48:43-50. adipokines and hormones of obesity in childhood asthma.
  • Allergy Asthma Immunol Res 2012;4(2):98-103. http://dx.doi.org/10.4168/aair.2012.4.2.98
  • Balducci Mt, Petruzzelli l, et al. Obesity can influence children’s and adolescents’ airway hyperresponsiveness diffe- rently. Multidiscip Respir Med 2013;12:8(1):60.
There are 22 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Mahmut Doğru This is me

İlknur Bostancı This is me

Serap Özmen This is me

Handan Duman Şenol This is me

Gülay Başarır This is me

Publication Date April 1, 2014
Published in Issue Year 2014

Cite

APA Doğru, M., Bostancı, İ., Özmen, S., Duman Şenol, H., et al. (2014). Çocuklarda Obezitenin Astıma Etkisi. Çocuk Dergisi, 14(2), 72-77. https://doi.org/10.5222/j.child.2014.072
AMA Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G. Çocuklarda Obezitenin Astıma Etkisi. Çocuk Dergisi. April 2014;14(2):72-77. doi:10.5222/j.child.2014.072
Chicago Doğru, Mahmut, İlknur Bostancı, Serap Özmen, Handan Duman Şenol, and Gülay Başarır. “Çocuklarda Obezitenin Astıma Etkisi”. Çocuk Dergisi 14, no. 2 (April 2014): 72-77. https://doi.org/10.5222/j.child.2014.072.
EndNote Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G (April 1, 2014) Çocuklarda Obezitenin Astıma Etkisi. Çocuk Dergisi 14 2 72–77.
IEEE M. Doğru, İ. Bostancı, S. Özmen, H. Duman Şenol, and G. Başarır, “Çocuklarda Obezitenin Astıma Etkisi”, Çocuk Dergisi, vol. 14, no. 2, pp. 72–77, 2014, doi: 10.5222/j.child.2014.072.
ISNAD Doğru, Mahmut et al. “Çocuklarda Obezitenin Astıma Etkisi”. Çocuk Dergisi 14/2 (April 2014), 72-77. https://doi.org/10.5222/j.child.2014.072.
JAMA Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G. Çocuklarda Obezitenin Astıma Etkisi. Çocuk Dergisi. 2014;14:72–77.
MLA Doğru, Mahmut et al. “Çocuklarda Obezitenin Astıma Etkisi”. Çocuk Dergisi, vol. 14, no. 2, 2014, pp. 72-77, doi:10.5222/j.child.2014.072.
Vancouver Doğru M, Bostancı İ, Özmen S, Duman Şenol H, Başarır G. Çocuklarda Obezitenin Astıma Etkisi. Çocuk Dergisi. 2014;14(2):72-7.