Invasive Meningococcal Disease and Vaccines

Abstract

Meningococcal diseases continue to have a major public health impact in many countries. Fatality rate of invasive meningococcal disease IMD in pediatric patients is 10 %. At least 75 % of cases of are caused byserogroups A, C, Y, and W-135; thus, IMD potentially is preventable by immu- nization. Plain polysaccharides vaccines for Neisseria meningit have been in use for approximately 20 years, both to prevent invasive disease in high-risk population and to control disease outbreaks. The preferred vaccine for people ages 2-55 years is Meningococcal conjugate vaccine MCV4

Keywords

• Meningococcal infections,meningococcal vaccines

İnvaziv Meningokok Hastalığı ve Aşıları

Abstract

Meningokok infeksiyonları bütün dünyada önemli sağlık sorunları arasında yer almaya devam etmektedir. İnvaziv Meningokok hastalığı çocukluk çağında % 10 oranında ölümcül olabilmektedir. Vakaların % 75’inden serogrup A, C, Y ve W135 sorumludur. İMH aşılama ile önlenebilir bir hastalıktır. İnfeksiyonların önlenmesi için uzun yıllardan beri iki yaşından itibaren uygulanan polisakkarid aşılar risk gruplarında ve salgın kontrolünde kullanılmaktadır. İki-55 yaş arasında tercih edilen aşı, meningokok konjuge aşıdır MCV4

Keywords

• Meningokok aşıları,meningokok infeksiyonu

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