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Bir Çocuk Vakada Enfekte Dev Lenfanjiom

Year 2016, Volume: 16 Issue: 1, 32 - 35, 01.02.2016
https://doi.org/10.5222/j.child.2016.032

Abstract

Amaç: Lenfanjiyomlar, lenfatik sistemin ender görülen konjenital proliferasyonudur. Dev lenfanjiomların seyri sırasında enfeksiyon, kanama, komşu dokularda destrüksiyona bağlı nekroz gibi komplikasyonlar gelişebilir. Burada sağ kolundaki dev lenfanjiyomu enfekte olmuş bir çocuk vaka sunulmuştur. Vaka Sunumu: Prenatal kistik lenfanjioma tanılı 4.5 yaşında kız hasta, sağ kolda şişlik, kızarıklık ve ısı artışı ile getirildi. Başvuru anında genel durumu düşkün olan hastanın ateşi 38.5°C idi. Fizik muayenesinde sağ üst ekstremitede üst kolda belirgin olmak üzere yaygın, ısı artışı ve hipereminin eşlik ettiği şişlik ile sağ toraks ön ve yan duvarında ülsere lezyon mevcuttu. Laboratuvar incelemede nötrofil hakimiyetinde lökositozu ve akut faz yüksekliği izlendi. Ultrasonografi incelemesi enfekte lenfanjiyom ile uyumlu bulunan hastaya ampisilin-sulbaktam tedavisi başlandı. Çekilen üst ekstremite ve toraks-batın manyetik rezonans görüntüleme MRG ’de sağ kolda seviyelenme veren, multiseptalı, hemorajik ve enfekte makrokistik lenfanjiom, toraksda en kalını 3 cm çapta makrokistik, birbiriyle ilişkisiz lenfanjiom saptandı. Ateşleri devam eden hastanın yara sürüntüsünden gönderilen kültürde metisilin dirençli koagülaz negatif stafilokok üremesi üzerine antibiyoterapisi teikoplaninmeropenem olarak düzenlendi. Plastik cerrahi ile konsülte edilen hastaya sklerozan etkisi nedeniyle lezyon içi tetrasiklin uygulandı. Enfeksiyonu kontrol altına alındıktan sonra mTOR inhibitörü sirolimus başlanan hasta izleme alındı. Sonuç: Lenfanjiyomlar, komplike olabilmeleri ve sendromlara eşlik edebilmeleri nedeniyle multidisipliner takip gerektirmektedir.

References

  • Fleischer ac, manning Fa, Jeanty P, romero r. Sonography in obstetrics and gynecology. 5th ed. London: Appleton-Lange, 1996; 393-394.
  • azouz H, Salah H, al-ajlan S, et al. Treatment of cystic hygroma in a young infant through multidiscip- linary approach involving sirolimus, sclerotherapy, and debulking surgery. JAAD Case Reports 2016;2:350-3. https://doi.org/10.1016/j.jdcr.2016.05.019
  • Dahnert W. Radiology review manual. 3th ed. Baltimore: Williams – Wilkins. 1996;285.
  • öztürk a, Sırmatel ö, Gültekin e, Bitiren e. Dev kistik higroma: prenatal tanı ve bulgular. Turk J Diagn Intervent Radiol 2002;8:407-9.
  • Wassef m, Blei F, adams D, et al. Vascular anomalies classification: Recommendations from the internatio- nal Society for the Study of Vascular Anomalies. Pediatrics 2015; 136:e203. https://doi.org/10.1542/peds.2014-3673
  • Kennedy Tl, Whitaker m, Pellitteri P, et al. Cystic hygroma / lympangioma: A rational approach to mana- gement. Laryngoscope 2001;111:1929-37. https://doi.org/10.1097/00005537-200111000-00011
  • Brumfield cG, Wenstrom KD, Davis rO, Owen J, cosper P. Second – trimester cystic hygroma: progno- sis of septated and nonseptated lesions. Obstet Gynecol 1996;88:979-82. https://doi.org/10.1016/S0029-7844(96)00358-4
  • niramis r, Watanatittan S, rattanasuwan T. Treatment of cystic hygroma by intralesional bleomy- cin injection: experience in 70 patients. Eur J Pediatr Surg 2010;20(3):178-82. https://doi.org/10.1055/s-0030-1247548
  • mirza B. ıjaz l, Saleem m, Sharif m, Sheikh a. Cystic hygroma: an overview. J Cutan Aesthet Surg 2010;3(3):139-44. https://doi.org/10.4103/0974-2077.74488
  • Huber S, Bruns cJ, Schmid G. Inhibition of the mam- malian target of rapamycin impedes lymphangiogene- sis. Kidney Int 2007;71(8):771-7. https://doi.org/10.1038/sj.ki.5002112

An Infected Giant Lymphangioma in a Child

Year 2016, Volume: 16 Issue: 1, 32 - 35, 01.02.2016
https://doi.org/10.5222/j.child.2016.032

Abstract

Introduction: Lymphangiomas are rare congenital proliferations of lymphatic system. Complications like infection, hemorrhage, necrosis related to compression in adjacent tissue can be seen during the follow-up of giant lymphangiomas. Herein, we present a child case with infected giant lymphangioma on his right arm. Case Report: A 4.5- year- old girl with the prenatal diagnosis of cystic lymphangioma presented with redness, swelling and hyperemia on her right arm. She was illappeared at admission and had a fever of 38.5°C. There was a diffuse, and marked swelling of the right forearm associated with increased fever and hyperemia and an ulcerated lesion on anterior, and lateral wall of the right hemithorax. Laboratory examination revealed neutrophilic leucocytosis and an increase in acute phase reactants. Ultrasonographic examination was consistent with infected lymphangioma and she was started on ampicillinsulbactam treatment. Mangetic resonance imaging of right exremity, thorax and abdomen revealed multiseptate, hemorhagic and infected macrocystic lymphangioma unrelated with another macrocystic lymphangioma 3 cm in diameter on her right chest. Her fever persisted and her antibiotherapy was switched to teicoplanin and meropenem since her swab sample culture yielded growth of methicillin- resistant coagulase-negative staphylococcus growth. Because of its sclerosing effect intralesional tetracycline was administered after consultation with plastic surgery. Sirolimus mTOR inhibitor treatment was started after the control of infection was achieved.

References

  • Fleischer ac, manning Fa, Jeanty P, romero r. Sonography in obstetrics and gynecology. 5th ed. London: Appleton-Lange, 1996; 393-394.
  • azouz H, Salah H, al-ajlan S, et al. Treatment of cystic hygroma in a young infant through multidiscip- linary approach involving sirolimus, sclerotherapy, and debulking surgery. JAAD Case Reports 2016;2:350-3. https://doi.org/10.1016/j.jdcr.2016.05.019
  • Dahnert W. Radiology review manual. 3th ed. Baltimore: Williams – Wilkins. 1996;285.
  • öztürk a, Sırmatel ö, Gültekin e, Bitiren e. Dev kistik higroma: prenatal tanı ve bulgular. Turk J Diagn Intervent Radiol 2002;8:407-9.
  • Wassef m, Blei F, adams D, et al. Vascular anomalies classification: Recommendations from the internatio- nal Society for the Study of Vascular Anomalies. Pediatrics 2015; 136:e203. https://doi.org/10.1542/peds.2014-3673
  • Kennedy Tl, Whitaker m, Pellitteri P, et al. Cystic hygroma / lympangioma: A rational approach to mana- gement. Laryngoscope 2001;111:1929-37. https://doi.org/10.1097/00005537-200111000-00011
  • Brumfield cG, Wenstrom KD, Davis rO, Owen J, cosper P. Second – trimester cystic hygroma: progno- sis of septated and nonseptated lesions. Obstet Gynecol 1996;88:979-82. https://doi.org/10.1016/S0029-7844(96)00358-4
  • niramis r, Watanatittan S, rattanasuwan T. Treatment of cystic hygroma by intralesional bleomy- cin injection: experience in 70 patients. Eur J Pediatr Surg 2010;20(3):178-82. https://doi.org/10.1055/s-0030-1247548
  • mirza B. ıjaz l, Saleem m, Sharif m, Sheikh a. Cystic hygroma: an overview. J Cutan Aesthet Surg 2010;3(3):139-44. https://doi.org/10.4103/0974-2077.74488
  • Huber S, Bruns cJ, Schmid G. Inhibition of the mam- malian target of rapamycin impedes lymphangiogene- sis. Kidney Int 2007;71(8):771-7. https://doi.org/10.1038/sj.ki.5002112
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Serra Bülbül Acar This is me

Manolya Acar This is me

Selda Hançerli Törün This is me

Sevliya Öcal Demir This is me

Deniz Tuğcu This is me

Zeynep Karakaş This is me

Emine Çalışkan This is me

Nuran Salman This is me

Ayper Somer This is me

Publication Date February 1, 2016
Published in Issue Year 2016 Volume: 16 Issue: 1

Cite

APA Bülbül Acar, S., Acar, M., Hançerli Törün, S., Öcal Demir, S., et al. (2016). Bir Çocuk Vakada Enfekte Dev Lenfanjiom. Journal of Child, 16(1), 32-35. https://doi.org/10.5222/j.child.2016.032
AMA Bülbül Acar S, Acar M, Hançerli Törün S, Öcal Demir S, Tuğcu D, Karakaş Z, Çalışkan E, Salman N, Somer A. Bir Çocuk Vakada Enfekte Dev Lenfanjiom. Journal of Child. February 2016;16(1):32-35. doi:10.5222/j.child.2016.032
Chicago Bülbül Acar, Serra, Manolya Acar, Selda Hançerli Törün, Sevliya Öcal Demir, Deniz Tuğcu, Zeynep Karakaş, Emine Çalışkan, Nuran Salman, and Ayper Somer. “Bir Çocuk Vakada Enfekte Dev Lenfanjiom”. Journal of Child 16, no. 1 (February 2016): 32-35. https://doi.org/10.5222/j.child.2016.032.
EndNote Bülbül Acar S, Acar M, Hançerli Törün S, Öcal Demir S, Tuğcu D, Karakaş Z, Çalışkan E, Salman N, Somer A (February 1, 2016) Bir Çocuk Vakada Enfekte Dev Lenfanjiom. Journal of Child 16 1 32–35.
IEEE S. Bülbül Acar, “Bir Çocuk Vakada Enfekte Dev Lenfanjiom”, Journal of Child, vol. 16, no. 1, pp. 32–35, 2016, doi: 10.5222/j.child.2016.032.
ISNAD Bülbül Acar, Serra et al. “Bir Çocuk Vakada Enfekte Dev Lenfanjiom”. Journal of Child 16/1 (February 2016), 32-35. https://doi.org/10.5222/j.child.2016.032.
JAMA Bülbül Acar S, Acar M, Hançerli Törün S, Öcal Demir S, Tuğcu D, Karakaş Z, Çalışkan E, Salman N, Somer A. Bir Çocuk Vakada Enfekte Dev Lenfanjiom. Journal of Child. 2016;16:32–35.
MLA Bülbül Acar, Serra et al. “Bir Çocuk Vakada Enfekte Dev Lenfanjiom”. Journal of Child, vol. 16, no. 1, 2016, pp. 32-35, doi:10.5222/j.child.2016.032.
Vancouver Bülbül Acar S, Acar M, Hançerli Törün S, Öcal Demir S, Tuğcu D, Karakaş Z, Çalışkan E, Salman N, Somer A. Bir Çocuk Vakada Enfekte Dev Lenfanjiom. Journal of Child. 2016;16(1):32-5.