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Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi

Year 2015, Volume: 15 Issue: 1, 24 - 29, 01.01.2015
https://doi.org/10.5222/j.child.2015.024

Abstract

Amaç: Yenidoğan sarılığı yenidoğan bebeklerin en sık karşılaşılan klinik sorunlarından biridir. Çoğu kez çeşitli tedavi yöntemleri ile iyileşip düzelen bu klinik durum, erken tanı ve tedavi gerektiği durumlarda geç kalınırsa fatal sonuçlar doğurabilecek nörolojik komplikasyonlara yol açabilir.Gereç ve Yöntem: Çalışmamızda yenidoğan servisine indirekt hiperbilirubinemi nedeniyle yatırılan 103 bebek ile ayaktan yenidoğan polikliniğine kontrole gelen ve sarılığı saptanmayan 102 bebek değerlendirilmiştir.Bulgular: Çalışmaya alınan bebeklerin tamamı 37 ve üstü gestasyonel haftadaydı. Sarılık nedeniyle yatırılan bebeklerden 62’si %60.2 erkek, 41’i %39.8 kızdı. Bu bebeklerden 70’i %68 NSD ile 33’ü %32 sezaryen doğum ile doğmuştur. Bebekler en yüksek oranda %28.2 4. günlerinde hastaneye yatırılmışlardır. Doğum saatleri en kısa aralıklarla karşılaştırıldığında sarılık nedeniyle hastaneye yatırılan bebeklerden %33’ünün n=34 08:01 ile 12:00 saatleri arasında, %7.8’inin de n=8 04:01 ile 08:00 saatleri arasında doğduğu saptandı

References

  • mcmahon Jr, Stevenson DK, Oski FA. Physiologic Jaundice. In: Taeusch HW, Ballard RA, eds. Avery’s Disease of the Newborn 7th ed. Philadelphia, WB Saunders. 1998: 995-1002.
  • Hansen tW. Guidelines for treatment of neonatal jaundice. Is there a place for evidence - based medici- ne. Acta Pediatr 2001;90:292-95. http://dx.doi.org/10.1080/08035250117431
  • mc Donagh. Is bilirubin good for you? Clin Perinatol 1990;17:359-69.
  • Oran O, gurakan B. Bilirubin Metabolizması, Katkı Pediatri Dergisi 1995;16:667-9.
  • Huang mJ, Kua KE, teng HC, tang KS, Weng HW, Huang CS. Risk factors for severe hyperbilirubinemia in neonates. Pediatr Res 2004;56(5):682-9. http://dx.doi.org/10.1203/01.PDR.0000141846.37253.AF
  • newman tB, Xiong B, gonzales Vm, Escobar gJ. Prediction and prevention of extreme hyperbilirubine- mia in a mature health maintenance organization. Arch Pediatr Adolesc Med 2000;154:1140-7. http://dx.doi.org/10.1001/archpedi.154.11.1140
  • Ewing JF, maines mD. Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain. J Neurochem 1993;60:1512-9. http://dx.doi.org/10.1111/j.1471-4159.1993.tb03315.x
  • mendez-Sanchez n, roldan-Valadez E, Flores mA, Cardenas-Vazquez r, Uribe m. Zinc salts precipitate unconjugated bilirubin in vitro and inhibit enterohepa- tic cycling of bilirubin in hamsters. Eur J Clin Invest 2001;31:773-80. http://dx.doi.org/10.1046/j.1365-2362.2001.00879.x
  • mendez-Sanchez n, martinez m, gonzalez V, roldan-Valadez E, Flores mA, Uriebe m. Zinc Sulphate inhibits the enterohepatic circulation of unconjugated bilirubin in subjects with Gilbert syndro- me. Ann Hepatol 2002;1:40-3.
  • rana n, mishra S, Bhatnagar S, Paul V, Deorari AK, Agarwal r. Efficacy of zinc in reducing hyperbi- lirubinemia among at-risk neonates: A Randomized, Double-Blind, Placebo-Controlled Trial. Indian J Pediatr 2011;78:1073-107. http://dx.doi.org/10.1007/s12098-011-0407-z
  • American Acedemy of Pediatrics Subcommite on Neonatal Hyperbilirubinemia. Neonatal Jaundice and Kernicterus, Pediatrics 2001;108:763-5. http://dx.doi.org/10.1542/peds.108.3.763
  • Watchko JF, lin Z, Clark rH, Kelleher AS, Walker mW, Spitzer Ar. Complex multifactorial nature of significant hyperbilirubinemia in neonates. Pediatrics 2009;124;e868. http://dx.doi.org/10.1542/peds.2009-0460
  • Chen YJ, Chen WC, Chen Cm. Risk factors for hyperbilirubinemia in breastfed term neonates. Eur J Pediatr 2012;171:167-71. http://dx.doi.org/10.1007/s00431-011-1512-8
  • Osborn lm, reiff ml, Bolus r. Jaundice in the full- term neonate, Pediatrics 1984;73:520-5.
  • Phuapradit W, Chaturachinda K, Auntlamai S. Risk faktors for neonatal hyperbilirubinemia. Med Assoc Thai 1993;76:424-8.
  • De Amici D, Delmonte P, martinotti l, gasparoni A, Zizzi S, ramajoli ı, ramajoli F. Can anesthesiolo- gic strategies for caesarean section influence newborn jaundice? A retrospective and prospective study. Biol Neonate 2001;79:97-102. http://dx.doi.org/10.1159/000047074
  • Ho nK. Neonatal jaundice in Asia. Bailieres Clin Haematol 1992;5:131-42. http://dx.doi.org/10.1016/S0950-3536(11)80038-7
  • gartner lm. Breastfeeding and jaundice. J Perinatol 2001;21:25-9. http://dx.doi.org/10.1038/sj.jp.7210629
  • Chen J, Sadakata m, ıshida m, Sekizuka n, Sayama m. Baby massage ameliorates neonatal jaundice in full-term newborn infants. Tohoku J Exp Med 2011; 223:97-102. http://dx.doi.org/10.1620/tjem.223.97
  • gourley gr, Kreamer B, Arend r. The effect of diet on feces and jaundice during the first 3 weeks of life. Gastroenterology 1992;103:660-7.
  • Semmekrot BA, de Vries mC, gerrits gP, van Wieringen Pm. Optimal breastfeeding to prevent hyperbilirubinaemia in healthy, term newborns. Ned Tijdschr Geneeskd 2004;148:2016-9.

Evaluation of Relation Between Neonatal Hyperbilirubinemia and Time of Birth

Year 2015, Volume: 15 Issue: 1, 24 - 29, 01.01.2015
https://doi.org/10.5222/j.child.2015.024

Abstract

Objective: Hyperbilirubinemia is one of the most frequently encountered problems of neonates. Although there are several treatment options, it can lead to potentially fatal neurological consequences if appropriate intervention is delayed.Material and Methods: One hundred and three neonates who had been hospitalized for hyperbilirubinemia in our neonatalogy department and 102 healthy newborns without hyperbilirubinemia who applied to the neonatal service for control were evaluatedResults: All of the patients included in the study were born at ≥37 gestational weeks. Sixty two 60.2% were male. Among infants hospitalized because of jaundice 70 68% patients were male, while 41 39.8 % of them were female. Seventy 68 % babies were born with spontaneous vaginal birth, and 33 32 % of them via cesarean section Most frequently 28.2% . babies were hospitalized at 4. postnatal day among the patients who had been hospitalized for jaundice, 33% n=34 were born between 08:01 a.m. and 12:00 p.m, and 8 patients 7.8% between 04:01 a.m. and 08:00 a.m

References

  • mcmahon Jr, Stevenson DK, Oski FA. Physiologic Jaundice. In: Taeusch HW, Ballard RA, eds. Avery’s Disease of the Newborn 7th ed. Philadelphia, WB Saunders. 1998: 995-1002.
  • Hansen tW. Guidelines for treatment of neonatal jaundice. Is there a place for evidence - based medici- ne. Acta Pediatr 2001;90:292-95. http://dx.doi.org/10.1080/08035250117431
  • mc Donagh. Is bilirubin good for you? Clin Perinatol 1990;17:359-69.
  • Oran O, gurakan B. Bilirubin Metabolizması, Katkı Pediatri Dergisi 1995;16:667-9.
  • Huang mJ, Kua KE, teng HC, tang KS, Weng HW, Huang CS. Risk factors for severe hyperbilirubinemia in neonates. Pediatr Res 2004;56(5):682-9. http://dx.doi.org/10.1203/01.PDR.0000141846.37253.AF
  • newman tB, Xiong B, gonzales Vm, Escobar gJ. Prediction and prevention of extreme hyperbilirubine- mia in a mature health maintenance organization. Arch Pediatr Adolesc Med 2000;154:1140-7. http://dx.doi.org/10.1001/archpedi.154.11.1140
  • Ewing JF, maines mD. Glutathione depletion induces heme oxygenase-1 (HSP32) mRNA and protein in rat brain. J Neurochem 1993;60:1512-9. http://dx.doi.org/10.1111/j.1471-4159.1993.tb03315.x
  • mendez-Sanchez n, roldan-Valadez E, Flores mA, Cardenas-Vazquez r, Uribe m. Zinc salts precipitate unconjugated bilirubin in vitro and inhibit enterohepa- tic cycling of bilirubin in hamsters. Eur J Clin Invest 2001;31:773-80. http://dx.doi.org/10.1046/j.1365-2362.2001.00879.x
  • mendez-Sanchez n, martinez m, gonzalez V, roldan-Valadez E, Flores mA, Uriebe m. Zinc Sulphate inhibits the enterohepatic circulation of unconjugated bilirubin in subjects with Gilbert syndro- me. Ann Hepatol 2002;1:40-3.
  • rana n, mishra S, Bhatnagar S, Paul V, Deorari AK, Agarwal r. Efficacy of zinc in reducing hyperbi- lirubinemia among at-risk neonates: A Randomized, Double-Blind, Placebo-Controlled Trial. Indian J Pediatr 2011;78:1073-107. http://dx.doi.org/10.1007/s12098-011-0407-z
  • American Acedemy of Pediatrics Subcommite on Neonatal Hyperbilirubinemia. Neonatal Jaundice and Kernicterus, Pediatrics 2001;108:763-5. http://dx.doi.org/10.1542/peds.108.3.763
  • Watchko JF, lin Z, Clark rH, Kelleher AS, Walker mW, Spitzer Ar. Complex multifactorial nature of significant hyperbilirubinemia in neonates. Pediatrics 2009;124;e868. http://dx.doi.org/10.1542/peds.2009-0460
  • Chen YJ, Chen WC, Chen Cm. Risk factors for hyperbilirubinemia in breastfed term neonates. Eur J Pediatr 2012;171:167-71. http://dx.doi.org/10.1007/s00431-011-1512-8
  • Osborn lm, reiff ml, Bolus r. Jaundice in the full- term neonate, Pediatrics 1984;73:520-5.
  • Phuapradit W, Chaturachinda K, Auntlamai S. Risk faktors for neonatal hyperbilirubinemia. Med Assoc Thai 1993;76:424-8.
  • De Amici D, Delmonte P, martinotti l, gasparoni A, Zizzi S, ramajoli ı, ramajoli F. Can anesthesiolo- gic strategies for caesarean section influence newborn jaundice? A retrospective and prospective study. Biol Neonate 2001;79:97-102. http://dx.doi.org/10.1159/000047074
  • Ho nK. Neonatal jaundice in Asia. Bailieres Clin Haematol 1992;5:131-42. http://dx.doi.org/10.1016/S0950-3536(11)80038-7
  • gartner lm. Breastfeeding and jaundice. J Perinatol 2001;21:25-9. http://dx.doi.org/10.1038/sj.jp.7210629
  • Chen J, Sadakata m, ıshida m, Sekizuka n, Sayama m. Baby massage ameliorates neonatal jaundice in full-term newborn infants. Tohoku J Exp Med 2011; 223:97-102. http://dx.doi.org/10.1620/tjem.223.97
  • gourley gr, Kreamer B, Arend r. The effect of diet on feces and jaundice during the first 3 weeks of life. Gastroenterology 1992;103:660-7.
  • Semmekrot BA, de Vries mC, gerrits gP, van Wieringen Pm. Optimal breastfeeding to prevent hyperbilirubinaemia in healthy, term newborns. Ned Tijdschr Geneeskd 2004;148:2016-9.
There are 21 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ersen Acar This is me

Hasan Önal This is me

Servet Erdal Adal This is me

Publication Date January 1, 2015
Published in Issue Year 2015 Volume: 15 Issue: 1

Cite

APA Acar, E., Önal, H., & Adal, S. E. (2015). Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi. Çocuk Dergisi, 15(1), 24-29. https://doi.org/10.5222/j.child.2015.024
AMA Acar E, Önal H, Adal SE. Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi. Çocuk Dergisi. January 2015;15(1):24-29. doi:10.5222/j.child.2015.024
Chicago Acar, Ersen, Hasan Önal, and Servet Erdal Adal. “Yenidoğan Sarılıklarının Doğum Saati Ile İlişkisinin Değerlendirilmesi”. Çocuk Dergisi 15, no. 1 (January 2015): 24-29. https://doi.org/10.5222/j.child.2015.024.
EndNote Acar E, Önal H, Adal SE (January 1, 2015) Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi. Çocuk Dergisi 15 1 24–29.
IEEE E. Acar, H. Önal, and S. E. Adal, “Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi”, Çocuk Dergisi, vol. 15, no. 1, pp. 24–29, 2015, doi: 10.5222/j.child.2015.024.
ISNAD Acar, Ersen et al. “Yenidoğan Sarılıklarının Doğum Saati Ile İlişkisinin Değerlendirilmesi”. Çocuk Dergisi 15/1 (January 2015), 24-29. https://doi.org/10.5222/j.child.2015.024.
JAMA Acar E, Önal H, Adal SE. Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi. Çocuk Dergisi. 2015;15:24–29.
MLA Acar, Ersen et al. “Yenidoğan Sarılıklarının Doğum Saati Ile İlişkisinin Değerlendirilmesi”. Çocuk Dergisi, vol. 15, no. 1, 2015, pp. 24-29, doi:10.5222/j.child.2015.024.
Vancouver Acar E, Önal H, Adal SE. Yenidoğan Sarılıklarının Doğum Saati ile İlişkisinin Değerlendirilmesi. Çocuk Dergisi. 2015;15(1):24-9.