Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu

Ayhan Abacı; Aydın Çelik; Zülfikar Akelma; Zekai Avcı; Cem Hasan Razi; Osman Özdemir

doi:10.5222/j.child.2010.156

Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu

Year 2010, Volume: 10 Issue: 3, 156 - 158, 01.07.2010

Ayhan Abacı Aydın Çelik Zülfikar Akelma Zekai Avcı Cem Hasan Razi Osman Özdemir

https://doi.org/10.5222/j.child.2010.156

Abstract

On dört yaşında kız hasta meme gelişiminin olmaması ve adet görmeme nedeniyle başvurdu. Bazal hormonal değer- lendirme sonuçları hipogonadotropik hipogonadizm ile uyumluydu. Over ve uterus volümleri prepubertal boyutlar- da ve karyotipi 46 XX olarak saptandı. Hipogonadotropik hipogonadizm etiyolojisi nedeniyle yapılan hipofiz görün- tülemesinde boş sella saptandı. Bu vaka sunumu ile puber- te gecikmesiyle başvuran kız hastalarda hipogonadotropik hipogonadizm ayırıcı tanısında özellikle boş sella sendro- mu olmak üzere organik patolojilerin göz önüne alınması gerekliliğini ve bu vakalarda görüntüleme çalışmalarının önemini vurgulamak istedik

Keywords

Gecikmiş puberte, hipogonadotropik hipogonadizm, boş sella sendromu

References

1. Hoffman B, Bradshaw KD. Delayed puberty and amenorrhea. Semin Reprod Med 2003; 21:353-62.
2. Viswanathan V, Eugster EA. Etiology and treatment of hypogonadism in adolescents. Endocrinol Metab Clin North Am 2009; 38:719-38.
3. Nass R, Engel M, Stoner E, Pang S, New MI. Empty sella syndrome in childhood. Pediatr Neurol 1986; 2:224-9.
4. Cacciari E, Zucchini S, Ambrosetto P, et al. Empty sella in children and adolescents with possible hypothalamic-pituitary disorders. J Clin Endocrinol Metab 1994; 78:767-71.
5. Bjerre P. The empty sella. A reappraisal of etiology and pathogenesis. Acta Neurol Scand Suppl 1990;130:1-25.
6. De ML, Bonadonna S, Bianchi A, Maira G, Giustina A. Primary empty sella. J Clin Endocrinol Metab 2005; 90(9):5471-7.
7. Shulman DI, Martinez CR, Bercu BB, Root AW. Hypothalamic-pituitary dysfunction in primary empty sella syndrome in childhood. J Pediatr 1986; 108:540-4.
8. gli Uberti EC, Teodori V, Trasforini G, et al. The empty sella syndrome. Clinical, radiological and endocrinologic analysis in 20 cases. Minerva Endocrinol 1989; 14:1-18.
9. Maira G, Anile C, Mangiola A. Primary empty sella syndrome in a series of 142 patients. J Neurosurg 2005;103:831-6.
10. Gray WC, Salcman M, Rao K, Leveque H. CSF rhinorrhea associated with the empty-sella syndrome. Arch Otolaryngol 1980; 106:302-5.
11. Sindler BH, Griffing GT, Melby JC. Primary empty sella syndrome, ACTH hypersecretion, and normal adrenocortical function. Report of two cases. Am J Med 1982; 73:449-54.
12. Guinto G, del VR, Nishimura E, Mercado M, Nettel B, Salazar F. Primary empty sella syndrome: the role of visual system herniation. Surg Neurol 2002; 58:42-7.

A Cause of Delayed Puberty: Empty Sella Syndrome

Year 2010, Volume: 10 Issue: 3, 156 - 158, 01.07.2010

Ayhan Abacı Aydın Çelik Zülfikar Akelma Zekai Avcı Cem Hasan Razi Osman Özdemir

https://doi.org/10.5222/j.child.2010.156

Abstract

A 14-year-old girl was admitted due to lack of breast deve- lopment and amenorrhea. The results of basal hormone studies were consistent with hypogonadotropic hypogona- dism. The uterine and ovarian sizes were of prepubertal dimensions, and the karyotype was found as 46 XX. Pituitary imaging for the etiology of hypogonadotropic hypogonadism revealed empty sella syndrome. Here, we wanted to emphasize the necessity of considering organic pituitary pathologies, particularly empty sella syndrome, in the differential diagnosis of hypogonadotropic hypogo- nadism and the importance of imaging studies in such cases

Keywords

Delayed puberty, hypogonadotropic hypogonadism, empty sella syndrome

References

1. Hoffman B, Bradshaw KD. Delayed puberty and amenorrhea. Semin Reprod Med 2003; 21:353-62.
2. Viswanathan V, Eugster EA. Etiology and treatment of hypogonadism in adolescents. Endocrinol Metab Clin North Am 2009; 38:719-38.
3. Nass R, Engel M, Stoner E, Pang S, New MI. Empty sella syndrome in childhood. Pediatr Neurol 1986; 2:224-9.
4. Cacciari E, Zucchini S, Ambrosetto P, et al. Empty sella in children and adolescents with possible hypothalamic-pituitary disorders. J Clin Endocrinol Metab 1994; 78:767-71.
5. Bjerre P. The empty sella. A reappraisal of etiology and pathogenesis. Acta Neurol Scand Suppl 1990;130:1-25.
6. De ML, Bonadonna S, Bianchi A, Maira G, Giustina A. Primary empty sella. J Clin Endocrinol Metab 2005; 90(9):5471-7.
7. Shulman DI, Martinez CR, Bercu BB, Root AW. Hypothalamic-pituitary dysfunction in primary empty sella syndrome in childhood. J Pediatr 1986; 108:540-4.
8. gli Uberti EC, Teodori V, Trasforini G, et al. The empty sella syndrome. Clinical, radiological and endocrinologic analysis in 20 cases. Minerva Endocrinol 1989; 14:1-18.
9. Maira G, Anile C, Mangiola A. Primary empty sella syndrome in a series of 142 patients. J Neurosurg 2005;103:831-6.
10. Gray WC, Salcman M, Rao K, Leveque H. CSF rhinorrhea associated with the empty-sella syndrome. Arch Otolaryngol 1980; 106:302-5.
11. Sindler BH, Griffing GT, Melby JC. Primary empty sella syndrome, ACTH hypersecretion, and normal adrenocortical function. Report of two cases. Am J Med 1982; 73:449-54.
12. Guinto G, del VR, Nishimura E, Mercado M, Nettel B, Salazar F. Primary empty sella syndrome: the role of visual system herniation. Surg Neurol 2002; 58:42-7.

There are 12 citations in total.

Details

Primary Language	Turkish
Journal Section	Research Articles
Authors	Ayhan Abacı This is me Aydın Çelik This is me Zülfikar Akelma This is me Zekai Avcı This is me Cem Hasan Razi This is me Osman Özdemir This is me
Publication Date	July 1, 2010
Published in Issue	Year 2010 Volume: 10 Issue: 3

Cite

APA	Abacı, A., Çelik, A., Akelma, Z., Avcı, Z., et al. (2010). Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu. Çocuk Dergisi, 10(3), 156-158. https://doi.org/10.5222/j.child.2010.156
AMA	Abacı A, Çelik A, Akelma Z, Avcı Z, Razi CH, Özdemir O. Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu. Çocuk Dergisi. July 2010;10(3):156-158. doi:10.5222/j.child.2010.156
Chicago	Abacı, Ayhan, Aydın Çelik, Zülfikar Akelma, Zekai Avcı, Cem Hasan Razi, and Osman Özdemir. “Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu”. Çocuk Dergisi 10, no. 3 (July 2010): 156-58. https://doi.org/10.5222/j.child.2010.156.
EndNote	Abacı A, Çelik A, Akelma Z, Avcı Z, Razi CH, Özdemir O (July 1, 2010) Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu. Çocuk Dergisi 10 3 156–158.
IEEE	A. Abacı, A. Çelik, Z. Akelma, Z. Avcı, C. H. Razi, and O. Özdemir, “Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu”, Çocuk Dergisi, vol. 10, no. 3, pp. 156–158, 2010, doi: 10.5222/j.child.2010.156.
ISNAD	Abacı, Ayhan et al. “Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu”. Çocuk Dergisi 10/3 (July 2010), 156-158. https://doi.org/10.5222/j.child.2010.156.
JAMA	Abacı A, Çelik A, Akelma Z, Avcı Z, Razi CH, Özdemir O. Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu. Çocuk Dergisi. 2010;10:156–158.
MLA	Abacı, Ayhan et al. “Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu”. Çocuk Dergisi, vol. 10, no. 3, 2010, pp. 156-8, doi:10.5222/j.child.2010.156.
Vancouver	Abacı A, Çelik A, Akelma Z, Avcı Z, Razi CH, Özdemir O. Puberte Gecikmesinin Bir Nedeni: Boş Sella Sendromu. Çocuk Dergisi. 2010;10(3):156-8.