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Çocuklarda Alerjik Rinit

Year 2010, Volume: 10 Issue: 2, 62 - 68, 01.04.2010
https://doi.org/10.5222/j.child.2010.062

Abstract

Allerjik rinit en sık rastlanan allerjik hastalıktır. Prevalansı astım prevelansının 3 katıdır ve dünya çapında giderek artış göstermektedir. Tip 1 aracılıklı reaksiyon olup IgE bağımlı nazal mukozanın enflamasyonudur. Hayatı tehdit eden bir hastalık olmamasına rağmen hayat kalitesini düşürmekte, insanların iş ve okul başarılarını etkilemekte- dir. Doğrudan ve dolaylı olarak sağlık giderlerinde artışa yol açmaktadır. Bunun yanı sıra astımla birlikteliği sık olup zayıf astım kontrolüne ve artmış atak riskine yol açmaktadır. Tüm bu nedenlerden dolayı tanı ve tedavisi önem arz etmektedir. Bu yazıda güncel bilgiler eşliğinde allerjik rinit kliniği, patofizyolojisi, tanı ve tedavisi gözden geçirilmiştir

References

  • 1. Wallace DV, Dykewicz MS, Bernstein DI, Bernstein IL, Blessing-Moore J, Cox L et al. The Joint Force on Practice Parameters, representing the AAAAI, ACAAI, JCAAI. The diagnosis and management of rhinitis: An updated practice parameter. J Allergy Clin Immunol 2008; 122:S1-84.
  • 2. Orban NT, Saleh H, Durham SR. Allergic and Non-allergic Rhinitis. in: Adkinson NF, Holgate ST, Bochner BS, Lemanske RF, Buse W, Simons FE (eds). Middleton’s Allergy Principles&Practice. Seventh edition, China, Elsevier, 2009; 973-90.
  • 3. Asher MI, Montefort S, Bjorksten B, Lai CK, Stachan DP, Weiland SK et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC. Phases One and Three repeat multicountry crosssectional surveys. Lancet 2006; 68:733-43.
  • 4. Akçay A, Tamay Z, İnan M, Gürses D, Zencir M, Öneş Ü ve ark. Denizli’deki 13-14 yaş okul çocuklarında allerjik hastalık belirtilerinin yaygınlığı. Türk Pediatri Arşivi 2006; 41:81-6.
  • 5. Mısırlıoğlu ED, Cengizliler R. Perennial ve mevsimsel allerjik rinitli çocukların değerlendirilmesi. Astım Allerji İmmünoloji 2003; 1:11-6.
  • 6. Demoly P, Allaert F, Lecasble M, Bousquet J, PRAGMA. Validation of the classification of ARIA (allergic rhinitis and its impact on asthma). Allergy 2003; 58:672-5.
  • 7. Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol 2010; 125:103-15.
  • 8. Heppt W, Dinh QT, Cryer A, Zweng M, Noga O, Peiser C, et al. Phenotypic alteration of neuropeptide-containing nerve fibres in seasonal intermittent allergic rhinitis. Clin Exp Allergy 2004; 34:1105-10.
  • 9. Ellegard EK. Pregnancy rhinitis. Immunol Allergy Clin North Am 2006;26:119-35.
  • 10. Szczeklik A, Nizankowska E, Duplaga M. Natural History of Aspirin-Induced asthma. Eur Respir J 2000; 16:432-6.
  • 11. Kramer MF, de la Chaux R, Fintelmann R, Rasp G. NARES: A risk factor for obstructive sleep apnea? Am J Otolaryngol 2004; 25:173-7.
  • 12. Moore EJ, Kern EB. Atrophic rhinitis: a review of 242 cases. Am J Rhinol 2001; 15:355-61.
  • 13. Bousquet J, Bachert C, Canonica G.W, Casala TB, Cruz AA, Lockey RJ, et al. Unmet needs in severe chronic upper airway disease (SCUAD). J Allergy Clin Immunol 2009; 124:428-33.
  • 14. Craig TJ, McCann JL, Gurevich F, Davies MJ. The correlation between allergic rhinitis and sleep disturbance. J Allergy Clin Immunol 2004; 114:139-45.
  • 15. Casale T.B, Dykewicz M.S. Clinical implications of the allergic rhinitis-asthma link. Am J Med Sci 2004; 327:127-138.
  • 16. Nathan RA. The burden of allergic rhinitis. Allergy Asthma Proc 2007; 28:3-9.
  • 17. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and Its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008; 63:8-160.
  • 18. Min YG. The pathophysiology, diagnosis and treatment of allergic rhinitis. Allergy Asthma Immunol Res 2010; 2:65- 76.
  • 19. Takeno S, Osada R, Furukido K, Chen JH, Yajin K. Increased nitric oxide production in nasal epithelial cells from allergic patients – RT-PCR analysis and direct imaging by a fluorescence indicator: DAF-2DA. Clin Exp Allergy 2001;31:881-8.
  • 20. Deja M, Busch T, Bachmann S, Riskowski K, Campean V, Wiedmann B, et al: Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. Am J Respir Crit Care Med 2003; 168:281-6.
  • 21. Sheikh A, Hurwitz B, Shehata YA. House dust mite avoidance measures for perennial allergic rhinitis. The Cochrane Database of Systematic Reviews 2010 Issue 7. Art. No.: CD001563. DOI: 10.1002/14651858.CD001563.pub3 (Accessed by 31 December, 2009, at http://www2.cochrane. org/reviews/en/ab001563.html).
  • 22. Valero A, Serrano C, Bartrá J, Izquierdo I, Muñoz-Cano R, Mullol J, et al. Reduction of nasal volume after allergeninduced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study. J Investig Allergol Clin Immunol 2009; 19:488-93.
  • 23. Yáñez A, Rodrigo GJ. Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. Ann Allergy Asthma Immunol 2002; 89:479-84.
  • 24. Mucha SM, de Tineo M, Naclerio RM, Baroody FM. Comparison of montelukast and pseudoephedrine in the treatment of allergic rhinitis. Arch Otolaryngol Head Neck Surg 2006; 132:164-72.
  • 25. Wilson AM, O’Byrne PM, Parameswaran K. Leukotrien receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. Am J Med 2004; 116:338-44.
  • 26. Chervinsky P, Casale TB, Townley R, Tripathy I, Hedgecock S, Fowler-Taylor A et al. Omalizumab, an antiIgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis. Ann Allergy Asthma Immunol 2003; 91:160-7.
  • 27. Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007; 120(suppl):S25-85.
  • 28. Kılıç GÇ, Kardeş B, Çefle A, Yazıcı A. Mevsimsel allerjik rinitli hastalarda mevsim öncesi immünoterapinin etkinliği. İst Tıp Fak Derg 2008; 71:65-72.
  • 29. Can D, Tanaç R, Demir E, Gülen F, Veral A. Efficacy of pollen immunotherapy in seasonal allergic rhinitis. Pediatr Int. 2007; 49:64-9.

Allergic Rhinitis in Children

Year 2010, Volume: 10 Issue: 2, 62 - 68, 01.04.2010
https://doi.org/10.5222/j.child.2010.062

Abstract

Allergic rhinitis is the most common allergic disease. The prevalence of allergic rhinitis is at least 3 times that of asthma and is increasing worldwide. It is a type 1 reaction which is an IgE mediated inflammation of the nasal muco- sa. While allergic rhinitis is not a life-threatening conditi- on, it can impair quality of life and influence the work and school performance. Also it increases the health care costs by direct and indirect ways. On the other hand it often presents together with asthma and is associated with poor asthma control and increases the risk of exacerbations. Because of all these reasons, its diagnosis and treatment is important. In this article, clinic, pathophysiology, diagno- sis and treatment of allergic rhinitis is reviewed in the light of current literature

References

  • 1. Wallace DV, Dykewicz MS, Bernstein DI, Bernstein IL, Blessing-Moore J, Cox L et al. The Joint Force on Practice Parameters, representing the AAAAI, ACAAI, JCAAI. The diagnosis and management of rhinitis: An updated practice parameter. J Allergy Clin Immunol 2008; 122:S1-84.
  • 2. Orban NT, Saleh H, Durham SR. Allergic and Non-allergic Rhinitis. in: Adkinson NF, Holgate ST, Bochner BS, Lemanske RF, Buse W, Simons FE (eds). Middleton’s Allergy Principles&Practice. Seventh edition, China, Elsevier, 2009; 973-90.
  • 3. Asher MI, Montefort S, Bjorksten B, Lai CK, Stachan DP, Weiland SK et al. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC. Phases One and Three repeat multicountry crosssectional surveys. Lancet 2006; 68:733-43.
  • 4. Akçay A, Tamay Z, İnan M, Gürses D, Zencir M, Öneş Ü ve ark. Denizli’deki 13-14 yaş okul çocuklarında allerjik hastalık belirtilerinin yaygınlığı. Türk Pediatri Arşivi 2006; 41:81-6.
  • 5. Mısırlıoğlu ED, Cengizliler R. Perennial ve mevsimsel allerjik rinitli çocukların değerlendirilmesi. Astım Allerji İmmünoloji 2003; 1:11-6.
  • 6. Demoly P, Allaert F, Lecasble M, Bousquet J, PRAGMA. Validation of the classification of ARIA (allergic rhinitis and its impact on asthma). Allergy 2003; 58:672-5.
  • 7. Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol 2010; 125:103-15.
  • 8. Heppt W, Dinh QT, Cryer A, Zweng M, Noga O, Peiser C, et al. Phenotypic alteration of neuropeptide-containing nerve fibres in seasonal intermittent allergic rhinitis. Clin Exp Allergy 2004; 34:1105-10.
  • 9. Ellegard EK. Pregnancy rhinitis. Immunol Allergy Clin North Am 2006;26:119-35.
  • 10. Szczeklik A, Nizankowska E, Duplaga M. Natural History of Aspirin-Induced asthma. Eur Respir J 2000; 16:432-6.
  • 11. Kramer MF, de la Chaux R, Fintelmann R, Rasp G. NARES: A risk factor for obstructive sleep apnea? Am J Otolaryngol 2004; 25:173-7.
  • 12. Moore EJ, Kern EB. Atrophic rhinitis: a review of 242 cases. Am J Rhinol 2001; 15:355-61.
  • 13. Bousquet J, Bachert C, Canonica G.W, Casala TB, Cruz AA, Lockey RJ, et al. Unmet needs in severe chronic upper airway disease (SCUAD). J Allergy Clin Immunol 2009; 124:428-33.
  • 14. Craig TJ, McCann JL, Gurevich F, Davies MJ. The correlation between allergic rhinitis and sleep disturbance. J Allergy Clin Immunol 2004; 114:139-45.
  • 15. Casale T.B, Dykewicz M.S. Clinical implications of the allergic rhinitis-asthma link. Am J Med Sci 2004; 327:127-138.
  • 16. Nathan RA. The burden of allergic rhinitis. Allergy Asthma Proc 2007; 28:3-9.
  • 17. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, et al. Allergic Rhinitis and Its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen). Allergy 2008; 63:8-160.
  • 18. Min YG. The pathophysiology, diagnosis and treatment of allergic rhinitis. Allergy Asthma Immunol Res 2010; 2:65- 76.
  • 19. Takeno S, Osada R, Furukido K, Chen JH, Yajin K. Increased nitric oxide production in nasal epithelial cells from allergic patients – RT-PCR analysis and direct imaging by a fluorescence indicator: DAF-2DA. Clin Exp Allergy 2001;31:881-8.
  • 20. Deja M, Busch T, Bachmann S, Riskowski K, Campean V, Wiedmann B, et al: Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. Am J Respir Crit Care Med 2003; 168:281-6.
  • 21. Sheikh A, Hurwitz B, Shehata YA. House dust mite avoidance measures for perennial allergic rhinitis. The Cochrane Database of Systematic Reviews 2010 Issue 7. Art. No.: CD001563. DOI: 10.1002/14651858.CD001563.pub3 (Accessed by 31 December, 2009, at http://www2.cochrane. org/reviews/en/ab001563.html).
  • 22. Valero A, Serrano C, Bartrá J, Izquierdo I, Muñoz-Cano R, Mullol J, et al. Reduction of nasal volume after allergeninduced rhinitis in patients treated with rupatadine: a randomized, cross-over, double-blind, placebo-controlled study. J Investig Allergol Clin Immunol 2009; 19:488-93.
  • 23. Yáñez A, Rodrigo GJ. Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. Ann Allergy Asthma Immunol 2002; 89:479-84.
  • 24. Mucha SM, de Tineo M, Naclerio RM, Baroody FM. Comparison of montelukast and pseudoephedrine in the treatment of allergic rhinitis. Arch Otolaryngol Head Neck Surg 2006; 132:164-72.
  • 25. Wilson AM, O’Byrne PM, Parameswaran K. Leukotrien receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. Am J Med 2004; 116:338-44.
  • 26. Chervinsky P, Casale TB, Townley R, Tripathy I, Hedgecock S, Fowler-Taylor A et al. Omalizumab, an antiIgE antibody, in the treatment of adults and adolescents with perennial allergic rhinitis. Ann Allergy Asthma Immunol 2003; 91:160-7.
  • 27. Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Allergen immunotherapy: a practice parameter second update. J Allergy Clin Immunol 2007; 120(suppl):S25-85.
  • 28. Kılıç GÇ, Kardeş B, Çefle A, Yazıcı A. Mevsimsel allerjik rinitli hastalarda mevsim öncesi immünoterapinin etkinliği. İst Tıp Fak Derg 2008; 71:65-72.
  • 29. Can D, Tanaç R, Demir E, Gülen F, Veral A. Efficacy of pollen immunotherapy in seasonal allergic rhinitis. Pediatr Int. 2007; 49:64-9.
There are 29 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Handan Duman This is me

Emine Dibek Mısırlıoğlu This is me

Tayfur Giniş This is me

İlknur Bostancı This is me

Publication Date April 1, 2010
Published in Issue Year 2010 Volume: 10 Issue: 2

Cite

APA Duman, H., Dibek Mısırlıoğlu, E., Giniş, T., Bostancı, İ. (2010). Çocuklarda Alerjik Rinit. Çocuk Dergisi, 10(2), 62-68. https://doi.org/10.5222/j.child.2010.062
AMA Duman H, Dibek Mısırlıoğlu E, Giniş T, Bostancı İ. Çocuklarda Alerjik Rinit. Çocuk Dergisi. April 2010;10(2):62-68. doi:10.5222/j.child.2010.062
Chicago Duman, Handan, Emine Dibek Mısırlıoğlu, Tayfur Giniş, and İlknur Bostancı. “Çocuklarda Alerjik Rinit”. Çocuk Dergisi 10, no. 2 (April 2010): 62-68. https://doi.org/10.5222/j.child.2010.062.
EndNote Duman H, Dibek Mısırlıoğlu E, Giniş T, Bostancı İ (April 1, 2010) Çocuklarda Alerjik Rinit. Çocuk Dergisi 10 2 62–68.
IEEE H. Duman, E. Dibek Mısırlıoğlu, T. Giniş, and İ. Bostancı, “Çocuklarda Alerjik Rinit”, Çocuk Dergisi, vol. 10, no. 2, pp. 62–68, 2010, doi: 10.5222/j.child.2010.062.
ISNAD Duman, Handan et al. “Çocuklarda Alerjik Rinit”. Çocuk Dergisi 10/2 (April 2010), 62-68. https://doi.org/10.5222/j.child.2010.062.
JAMA Duman H, Dibek Mısırlıoğlu E, Giniş T, Bostancı İ. Çocuklarda Alerjik Rinit. Çocuk Dergisi. 2010;10:62–68.
MLA Duman, Handan et al. “Çocuklarda Alerjik Rinit”. Çocuk Dergisi, vol. 10, no. 2, 2010, pp. 62-68, doi:10.5222/j.child.2010.062.
Vancouver Duman H, Dibek Mısırlıoğlu E, Giniş T, Bostancı İ. Çocuklarda Alerjik Rinit. Çocuk Dergisi. 2010;10(2):62-8.