BibTex RIS Cite

Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka

Year 2008, Volume: 8 Issue: 3, 191 - 193, 01.07.2008

Abstract

Bez dermatiti, sütçocuklarında en yaygın görülen hastalık- larından biri olup, en sık 9-12. aylarda rastlanır. Bez der- matitinin hafif formları kendiliğinden düzebilirken daha ciddi formları tıbbi tedaviye gereksinim duyar. Diğer topi- kal ajanlara yanıt alınamayan orta ve ciddi bez dermatit- lerinde kısa süreli, düşük potensli kortikosteroidler yararlı olabilir. Kullanılan kortikosteroid potent olduğunda veya uzun süreli kullanıldığında iatrojenik Cushing sendromuna neden olabilir. Bu çalışmada bez dermatiti tedavisi sırasın- da, topikal potent kortikosteroid olan klobetazol 17 propi- onat Dermovate % 0.05 krem kullanımı sonucu, iatroje- nik Cushing sendromu gelişen beş kız vaka sunulmuştur

References

  • Jordan WE, Lawson KD, Berg RW, Franxman JJ, Marrer AM. Diaper dermatitis: frequency and severity among a gene- ral infant population. Pediatr Dermatol 1986; 3:198-207.
  • Visscher MO, Chatterjee R, Munson KA, Bare DE, Hoath SB. Development of diaper rash in the newborn. Pediatr Dermatol 2000; 17:52-7.
  • Int J Dermatol 2004; 43:830-4. 2005; 18:124-35.
  • ous penetration of 14C cortisol in man. J Invest Dermatol 1967; 48:181-3.
  • Percutaneous absorption of hydrocortisone during and after the acute phase of dermatitis in children. Pediatr Dermatol 1988; 5:276-9.
  • ression due to topical steroid administration in an infant. Pediatr Int 2007; 49:242-4.
  • lanımına bağlı iyatrojenik cushing sendromu. Erciyes Tıp Dergisi (Erciyes Medical Journal) 2007; 2.
  • syndrome due to misuse of topical steroid. Pediatr Dermatol 2004; 21:561-3.
  • Pediatri. İstanbul: Nobel Tıp Kitapevleri, 2002: 85-99.
  • Benjamin L. Clinical correlates with diaper dermatitis. Pediatrician 1987; 14 Suppl 1:21-6.
  • Guven A, Karadeniz S, Aydin O, Akbalik M, Aydin M. Fatal disseminated cytomegalovirus infection in an infant with Cushing’s syndrome caused by topical steroid. Horm Res 2005; 64:35-8.
  • ids. Dermatol Online J 2003; 9:16.
  • effects of topical glucocorticosteroids. J Am Acad Dermatol 2006; 54:1-15; quiz 16-8.
  • secondary to topical corticosteroids abuse. Clin Endocrinol 2003; 58:795-6.
  • topical corticosteroid: a case report. Am J Med Sci 2007; 333:173-4.
  • N, Kurtoğlu S, (eds). Pediatrik Endokrinoloji. Ankara: Pediat- rik Endokrinoloji ve Oksoloji Derneği Yayınları, 2003: 361- 414.
  • MI. Super potent topical corticosteroid use associated with adrenal suppression: clinical considerations. J Am Acad Dermatol 1998; 38:318-21.
  • Glucocorticosteroid action on the immune system: molecular and cellular aspects. Clin Exp Rheumatol 1991; 9:413-23.

Five Cases of Iatrogenic Cushing’s Syndrome Due to the Use of A Topical Steroid in Diaper Dermatitis

Year 2008, Volume: 8 Issue: 3, 191 - 193, 01.07.2008

Abstract

Diaper dermatitis is one of the most common disorders in infants. The incidence of diaper dermatitis is highest in those between 9 and 12 months of age. While mild forms heal spontaneously, more severe forms may require medi- cal attention. A short duration of mild corticosteroid app- lication may be useful in moderate to severe cases of dia- per dermatitis which have not responded to other topical agents. Iatrogenic Cushing’s syndrome may be due to extended use of steroid or the potency of topical corticos- teroids. We report five cases of Cushing’s syndrome due to the use of a topical potent corticosteroid clobetazole 17 propionate 0.05 % cream in diaper dermatitis

References

  • Jordan WE, Lawson KD, Berg RW, Franxman JJ, Marrer AM. Diaper dermatitis: frequency and severity among a gene- ral infant population. Pediatr Dermatol 1986; 3:198-207.
  • Visscher MO, Chatterjee R, Munson KA, Bare DE, Hoath SB. Development of diaper rash in the newborn. Pediatr Dermatol 2000; 17:52-7.
  • Int J Dermatol 2004; 43:830-4. 2005; 18:124-35.
  • ous penetration of 14C cortisol in man. J Invest Dermatol 1967; 48:181-3.
  • Percutaneous absorption of hydrocortisone during and after the acute phase of dermatitis in children. Pediatr Dermatol 1988; 5:276-9.
  • ression due to topical steroid administration in an infant. Pediatr Int 2007; 49:242-4.
  • lanımına bağlı iyatrojenik cushing sendromu. Erciyes Tıp Dergisi (Erciyes Medical Journal) 2007; 2.
  • syndrome due to misuse of topical steroid. Pediatr Dermatol 2004; 21:561-3.
  • Pediatri. İstanbul: Nobel Tıp Kitapevleri, 2002: 85-99.
  • Benjamin L. Clinical correlates with diaper dermatitis. Pediatrician 1987; 14 Suppl 1:21-6.
  • Guven A, Karadeniz S, Aydin O, Akbalik M, Aydin M. Fatal disseminated cytomegalovirus infection in an infant with Cushing’s syndrome caused by topical steroid. Horm Res 2005; 64:35-8.
  • ids. Dermatol Online J 2003; 9:16.
  • effects of topical glucocorticosteroids. J Am Acad Dermatol 2006; 54:1-15; quiz 16-8.
  • secondary to topical corticosteroids abuse. Clin Endocrinol 2003; 58:795-6.
  • topical corticosteroid: a case report. Am J Med Sci 2007; 333:173-4.
  • N, Kurtoğlu S, (eds). Pediatrik Endokrinoloji. Ankara: Pediat- rik Endokrinoloji ve Oksoloji Derneği Yayınları, 2003: 361- 414.
  • MI. Super potent topical corticosteroid use associated with adrenal suppression: clinical considerations. J Am Acad Dermatol 1998; 38:318-21.
  • Glucocorticosteroid action on the immune system: molecular and cellular aspects. Clin Exp Rheumatol 1991; 9:413-23.
There are 18 citations in total.

Details

Primary Language Turkish
Journal Section Research Articles
Authors

Ali Ataş This is me

Alpay Çakmak This is me

Dost Zeyrek This is me

Salih Durak This is me

Publication Date July 1, 2008
Published in Issue Year 2008 Volume: 8 Issue: 3

Cite

APA Ataş, A., Çakmak, A., Zeyrek, D., Durak, S. (2008). Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka. Journal of Child, 8(3), 191-193.
AMA Ataş A, Çakmak A, Zeyrek D, Durak S. Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka. Journal of Child. July 2008;8(3):191-193.
Chicago Ataş, Ali, Alpay Çakmak, Dost Zeyrek, and Salih Durak. “Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka”. Journal of Child 8, no. 3 (July 2008): 191-93.
EndNote Ataş A, Çakmak A, Zeyrek D, Durak S (July 1, 2008) Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka. Journal of Child 8 3 191–193.
IEEE A. Ataş, A. Çakmak, D. Zeyrek, and S. Durak, “Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka”, Journal of Child, vol. 8, no. 3, pp. 191–193, 2008.
ISNAD Ataş, Ali et al. “Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka”. Journal of Child 8/3 (July 2008), 191-193.
JAMA Ataş A, Çakmak A, Zeyrek D, Durak S. Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka. Journal of Child. 2008;8:191–193.
MLA Ataş, Ali et al. “Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka”. Journal of Child, vol. 8, no. 3, 2008, pp. 191-3.
Vancouver Ataş A, Çakmak A, Zeyrek D, Durak S. Bez Dermatiti Nedeniyle Kullanılan Lokal Steroide Bağlı Gelişen İatrojenik Cushing Sendromlu Beş Vaka. Journal of Child. 2008;8(3):191-3.