Influenza Infection in Infants Under One Year of Age

Year 2022, Volume: 22 Issue: 1, 21 - 24, 18.05.2022

Mustafa Gençeli , Ozge Metin , Sevgi Pekcan , Yasemin Derya Gülseren , Mehmet Özdemir , Şükrü Güner , Ensar Karakaş

https://doi.org/10.26650/jchild.2022.890911

Abstract

Objective: Influenza virus infections are infectious agents which lead to epidemics and pandemics, are associated with severe morbidity and mortality, and still maintain their importance worldwide. This study was planned due to the fact that influenza virus infections are associated with complications and hospitalizations in infants under 1 year of age. Material and Method: 56 infants diagnosed with influenza between October 2017 and February 2018 were retrospectively evaluated. Results: Mean age of the patients was 5.6±2.1 (2-11) months. Of the patients; 46.5% were followed-up in an inpatient setting and 53.5% in an outpatient setting. 22 patients were diagnosed by polymerase chain reaction method and 34 by rapid antigen test. Of the patients; 53.5% (n=30) were followed-up with diagnosis of upper respiratory tract infections, 33.9% (n=19) with pneumonia, 10.7% (n=6) with sepsis and 1.7% (n=1) with encephalitis. Mean duration of hospital stay was determined to be 8.32 (2-38) days. Conclusion: Influenza virus infections cause a high rate of hospitalizations in infants younger than one year old, it is necessary to determine with fast and accurate diagnostic methods, to arrange their treatment and to provide appropriate isolation measures.

Keywords

Influenza, infant, polymerase chain reaction, rapid antigen testing

Supporting Institution

NO SUPPORTING INSTITUTION

Bir Yaş Altı İnfantlarda İnfluenza Enfeksiyonu

Abstract

Amaç: İnfluenza virüs enfeksiyonları epidemi ve pandemilerle seyreden, ciddi morbidite ve mortalite ile ilişkilendirilen, halen dünya genelinde önemini koruyan bir enfeksiyon etkenidir. Bir yaş altı infantlarda influenza virüs enfeksiyonlarının hospitalizasyon ve komplikasyonlarla ilişkisi olması sebebiyle bu çalışma planlanmıştır. Gereç ve Yöntem: Ekim 2017- Şubat 2018 tarihleri arasında influenza tanısı alan 56 infant retrospektif olarak değerlendirilmiştir. Bulgular: Hastaların ortalama yaşı 5,6±2,1 (2-11) ay idi. Hastaların %46,5’i hastaneye yatırılarak, %53,5’i ayaktan takip edildi. 22 hastaya polimeraz sincir reaksiyonu yöntemiyle, 34 hastaya hızlı antijen testi ile tanı konuldu. Hastaların %53,5’i (n=30) üst solunum yolu enfeksiyonu, %33,9’u (n=19) pnömoni, %10,7’si (n=6) sepsis, %1,7’si (n=1) ensefalit tanısıyla takip edildi. Ortalama yatış süresi 8,32 (2-38) gün olarak saptandı. Sonuç: İnfluenza virüs enfeksiyonları bir yaş altı infantlarda yüksek oranda hospitalizasyona sebep olmaktadır, hızlı ve doğru tanı yöntemleri ile belirlenerek tedavisinin düzenlenmesi ve uygun izolasyon önlemleri sağlanması gerekmektedir.

Keywords

infant, polimeraz zincir reaksiyonu, hızlı antijen testi

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