Abstract
Allergic rhinitis (AR), caused by IgE-mediated inflammation of the nasal mucosa due to allergens, affects 20-40% of Europe and the U.S. population, with varying prevalence in other regions. The study investigates the impact of allergic rhinitis (AR) on the quality of life (QOL) in school-aged children. It evaluates the effectiveness of the Pediatric Rhinitis Quality of Life Questionnaire (PRQLQ) in assessing disease severity and treatment outcomes. It uses the ARIA classification to categorize rhinitis severity. By analyzing QOL scores before and after treatment, the study assesses how well the PRQLQ reflects changes in disease severity and improves understanding of AR’s impact on children’s daily lives. The study used a prospective, longitudinal design to evaluate the impact of allergic rhinitis on children’s QOL before and after treatment. It included 120 children aged between 6-12 years, diagnosed with allergic rhinitis, and assessed using the Pediatric Rhinitis Quality of Life Questionnaire (PRQLQ) at the start and six weeks after treatment. Data were analyzed for changes in QOL scores across different rhinitis severity groups (via ARIA classification), considering sociodemographic factors and treatment effects. Results showed significant improvements in QOL scores post-treatment across all rhinitis groups. The PRQLQ scores, including subscales for nasal symptoms, eye symptoms, practical issues, and activity limitations, decreased significantly after treatment, indicating improved QOL. The study found that more severe rhinitis led to lower QOL before treatment, but significant improvements were noted in all groups after treatment. The PRQLQ effectively measured these changes and highlighted the substantial impact of allergic rhinitis on school-aged children’s daily lives, underscoring the importance of effective treatment in enhancing their quality of life.
References
- Bousquet J, van Cauwenberge P, Khaltaev N. Allergic Rhinitis and Its Impact on Asthma. Journal of Allergy and Clinical Immunology. 2001;108(5):S147-S334. google scholar
- Skoner DP. Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis. J Allergy Clin Immunol. 2001;108(1 Suppl):S2-8. google scholar
Abstract
Allergic rhinitis (AR), caused by IgE-mediated inflammation of the nasal mucosa due to allergens, affects 20-40% of Europe and the U.S. population, with varying prevalence in other regions. The study investigates the impact of allergic rhinitis (AR) on the quality of life (QOL) in school-aged children. It evaluates the effectiveness of the Pediatric Rhinitis Quality of Life Questionnaire (PRQLQ) in assessing disease severity and treatment outcomes. It uses the ARIA classification to categorize rhinitis severity. By analyzing QOL scores before and after treatment, the study assesses how well the PRQLQ reflects changes in disease severity and improves understanding of AR’s impact on children’s daily lives. The study used a prospective, longitudinal design to evaluate the impact of allergic rhinitis on children’s QOL before and after treatment. It included 120 children aged between 6-12 years, diagnosed with allergic rhinitis, and assessed using the Pediatric Rhinitis Quality of Life Questionnaire (PRQLQ) at the start and six weeks after treatment. Data were analyzed for changes in QOL scores across different rhinitis severity groups (via ARIA classification), considering sociodemographic factors and treatment effects. Results showed significant improvements in QOL scores post-treatment across all rhinitis groups. The PRQLQ scores, including subscales for nasal symptoms, eye symptoms, practical issues, and activity limitations, decreased significantly after treatment, indicating improved QOL. The study found that more severe rhinitis led to lower QOL before treatment, but significant improvements were noted in all groups after treatment. The PRQLQ effectively measured these changes and highlighted the substantial impact of allergic rhinitis on school-aged children’s daily lives, underscoring the importance of effective treatment in enhancing their quality of life.
Ethical Statement
This study is derived from a medical specialty thesis of Merve ERDEMİR KULA at Bezm-i Alem Foundation University, Faculty of Medicine, Department of Child Health and Diseases. The study was conducted with the approval of the Bezmialem Vakıf University Clinical Research Ethics Committee (approval number: 24/23). Informed consent was obtained from all participants involved in the research.
References
- Bousquet J, van Cauwenberge P, Khaltaev N. Allergic Rhinitis and Its Impact on Asthma. Journal of Allergy and Clinical Immunology. 2001;108(5):S147-S334. google scholar
- Skoner DP. Allergic rhinitis: definition, epidemiology, pathophysiology, detection, and diagnosis. J Allergy Clin Immunol. 2001;108(1 Suppl):S2-8. google scholar
Details
| Primary Language | English |
|---|---|
| Subjects | Infant and Child Health, Pediatric Immunology and Allergic Diseases |
| Journal Section | Research Article |
| Authors | |
| Publication Date | July 8, 2025 |
| Submission Date | September 20, 2024 |
| Acceptance Date | March 17, 2025 |
| Published in Issue | Year 2025 Volume: 25 Issue: 1 |