Ganoderma Lucıdum İle İlişkili Melena: Vaka Sunumu

Abstract

Giriş: Melena acil servis hastaları arasında görülen hayatı tehdit edebilecek bir bulgudur. Olgu Sunumu: Biz burada, önceden bilinen herhangi bir mide şikayeti olmayan genç bir erkek hastada Ganoderma Lucidum kullanımı ile indüklenen bir melena olgusu sunacağız. Sonuç: G. lucidum'un bazı toksik etkileri bildirilmiştir ancak bildiğimiz kadarıyla, bu vaka bildirilen G. lucidum ile ilişkili ilk üst gastrointestinal sistem kanamasıdır.

Keywords

• G. lucidum, melena, mantar

Melena Associated with Ganoderma lucidum: A Case Report

Abstract

Introduction: Melena is a life-threatening complaint of patients presenting to the emergency department.Case Report: Herein we present a case of Ganoderma luciduminduced melena in a young man who did not have any symptoms of gastrointestinal disease before. Conclusion: Some toxic effects of G. lucidum have been reported previously. However, to the best of our knowledge, this is the first case report of upper gastrointestinal bleeding associated with G. lucidum

Keywords

• G. lucidum, melena, mushroom

References

1. Pericleous M, Murray C, Hamilton M, Epstein O, Negus R, et al. Using an ‘action set’ for the management of acute upper gastrointestinal bleed- ing. Therap Adv Gastroenterol 2013; 6: 426-37. [CrossRef]
2. Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS. Ganoderma lu- cidum: a potent pharmacological macrofungus. Curr Pharm Biotechnol 2009; 10: 717-42. [CrossRef]
3. Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev 2012; 6: CD007731.
4. Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990; 10: 240-3. [CrossRef]
5. Su C, Shiao M, Wang C. Potentiation of ganodermic acid S on prosta- glandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res 2000; 99: 135-45. [CrossRef]
6. Kwok Y, Ng KF, Li CC, Lam CC, Man RY. A prospective, randomized, dou- ble-blind, placebo-controlled study of the platelet and global hemo- static effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005; 101: 423-6. [CrossRef]
7. Levitan D, Macy JI, Weissman J. Mechanism of gastrointestinal hemor- rhage in a case of mushroom poisoning by Chlorophyllum molybdites. Toxicon 1981; 19: 179-80. [CrossRef]
8. Gao Y, Zhou S, Wen J, Huang M, Xu A. Mechanism of the antiulcero- genic effect of Ganoderma lucidum polysaccharides on indomethacin- induced lesions in the rat. Life Sci 2002; 72: 731-45. [CrossRef]

9. Gao Y, Tang W, Gao H, Chan E, Lan J, Zhou S. Ganoderma lucidum poly- saccharide fractions accelerate healing of acetic acid-induced ulcers in rats. J Med Food 2004; 7: 417-21. [CrossRef]
10. Gill SK, Rieder MJ. Toxicity of a traditional Chinese medicine, Ganoder- ma lucidum, in children with cancer. Can J Clin Pharmacol 2008; 15: e275-85.