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A report of recurring pregnancy-induced Cushing's syndrome

Year 2020, , 13 - 16, 10.09.2020

Mitra Niafar , Amir Bahrami Fatemeh Ghorbani Nasser Aghamohammadzadeh Vahideh Sadra Nader Nader Djalal

https://doi.org/10.33706/jemcr.633840
Cited By: 1

Abstract

Introduction: The incidence of pregnancy-induced
Cushing's syndrome (CS) is very low. However, the diagnosis of CS in pregnant
patients is very difficult because of an overlapping signs and symptoms.

Case
report: Herein,
a 20-year-old pregnant patient was reported that was afflicted by gestational
CS during two pregnancies; termination of pregnancy was carried out in both
cases. Bilateral adrenal hypertrophy was reported in magnetic resonance
imaging. Following therapeutic abortion, signs of chemical evidence of CS was
thoroughly regressed within a few months after each abortion without any
treatment.





Conclusion: Due to the temporal relation between the
occurrence of CS after each pregnancy the diagnosis of gestational
hypercortisolism was made, and for further pregnancies bilateral adrenalectomy
was recommended.

Keywords

Cushing`s syndrome pregnancy

Supporting Institution

Tabriz University of Medical Sciences, Tabriz, Iran

Thanks

Authors would like to acknowledge Dr. Nader Nader Djalal at Department of Anesthesiology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA for his great help.

References

  • 1. Vilar L, Freitas Mda C, Lima LH, Lyra R, Kater CE. (2007). Cushing's syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol. 51(8):1293-302.
  • 2. Abbassy M, Kshettry VR, Hamrahian AH, Johnston PC, Dobri GA, Avitsian R, et al. (2015). Surgical management of recurrent Cushing's disease in pregnancy: A case report. Surg Neurol Int. 6(Suppl 25):S640-5.
  • 3. Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramides A. (2007). Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones-Athens. 6(3):242-46.
  • 4. Niafar M, Nader ND. (2015). Adiponectin as serum biomarker of insulin resistance in patients with polycystic ovarian syndrome. Gynecol Endocrinol. 31(6):473-6.
  • 5. Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. (2005). Cushing's syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab. 90(5):3077-83.
  • 6. Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. (2002). Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol. 105(2):189-91.
  • 7. Bevans JS, Gough MH, Gillmere MDG, Burke CW. (1987). Cushing’s syndrome in pregnancy: The timing of definitive treatment. Clinical Endocrinology. 27(2):225-33.
  • 8. Nassi R, Ladu C, Vezzosi C, Mannelli M. (2015). Cushing's syndrome in pregnancy. Gynecol Endocrinol. 31(2):102-4.
  • 9. Sam S, Molitch ME. (2003). Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 32(2):337-54.

Year 2020, , 13 - 16, 10.09.2020

Mitra Niafar , Amir Bahrami Fatemeh Ghorbani Nasser Aghamohammadzadeh Vahideh Sadra Nader Nader Djalal

https://doi.org/10.33706/jemcr.633840
Cited By: 1

Abstract

References

  • 1. Vilar L, Freitas Mda C, Lima LH, Lyra R, Kater CE. (2007). Cushing's syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol. 51(8):1293-302.
  • 2. Abbassy M, Kshettry VR, Hamrahian AH, Johnston PC, Dobri GA, Avitsian R, et al. (2015). Surgical management of recurrent Cushing's disease in pregnancy: A case report. Surg Neurol Int. 6(Suppl 25):S640-5.
  • 3. Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramides A. (2007). Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones-Athens. 6(3):242-46.
  • 4. Niafar M, Nader ND. (2015). Adiponectin as serum biomarker of insulin resistance in patients with polycystic ovarian syndrome. Gynecol Endocrinol. 31(6):473-6.
  • 5. Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. (2005). Cushing's syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab. 90(5):3077-83.
  • 6. Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. (2002). Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol. 105(2):189-91.
  • 7. Bevans JS, Gough MH, Gillmere MDG, Burke CW. (1987). Cushing’s syndrome in pregnancy: The timing of definitive treatment. Clinical Endocrinology. 27(2):225-33.
  • 8. Nassi R, Ladu C, Vezzosi C, Mannelli M. (2015). Cushing's syndrome in pregnancy. Gynecol Endocrinol. 31(2):102-4.
  • 9. Sam S, Molitch ME. (2003). Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 32(2):337-54.
There are 9 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Report
Authors

Mitra Niafar 0000-0002-9671-6286

Amir Bahrami This is me 0000-0002-4735-1196

Fatemeh Ghorbani This is me 0000-0002-6910-7960

Nasser Aghamohammadzadeh This is me 0000-0001-9402-0544

Vahideh Sadra This is me 0000-0003-3724-209X

Nader Nader Djalal 0000-0002-5744-7319

Publication Date September 10, 2020
Submission Date October 16, 2019
Published in Issue Year 2020

Cite

APA Niafar, M., Bahrami, A., Ghorbani, F., Aghamohammadzadeh, N., et al. (2020). A report of recurring pregnancy-induced Cushing’s syndrome. Journal of Emergency Medicine Case Reports, 11(1), 13-16. https://doi.org/10.33706/jemcr.633840
AMA Niafar M, Bahrami A, Ghorbani F, Aghamohammadzadeh N, Sadra V, Nader Djalal N. A report of recurring pregnancy-induced Cushing’s syndrome. Journal of Emergency Medicine Case Reports. September 2020;11(1):13-16. doi:10.33706/jemcr.633840
Chicago Niafar, Mitra, Amir Bahrami, Fatemeh Ghorbani, Nasser Aghamohammadzadeh, Vahideh Sadra, and Nader Nader Djalal. “A Report of Recurring Pregnancy-Induced Cushing’s Syndrome”. Journal of Emergency Medicine Case Reports 11, no. 1 (September 2020): 13-16. https://doi.org/10.33706/jemcr.633840.
EndNote Niafar M, Bahrami A, Ghorbani F, Aghamohammadzadeh N, Sadra V, Nader Djalal N (September 1, 2020) A report of recurring pregnancy-induced Cushing’s syndrome. Journal of Emergency Medicine Case Reports 11 1 13–16.
IEEE M. Niafar, A. Bahrami, F. Ghorbani, N. Aghamohammadzadeh, V. Sadra, and N. Nader Djalal, “A report of recurring pregnancy-induced Cushing’s syndrome”, Journal of Emergency Medicine Case Reports, vol. 11, no. 1, pp. 13–16, 2020, doi: 10.33706/jemcr.633840.
ISNAD Niafar, Mitra et al. “A Report of Recurring Pregnancy-Induced Cushing’s Syndrome”. Journal of Emergency Medicine Case Reports 11/1 (September 2020), 13-16. https://doi.org/10.33706/jemcr.633840.
JAMA Niafar M, Bahrami A, Ghorbani F, Aghamohammadzadeh N, Sadra V, Nader Djalal N. A report of recurring pregnancy-induced Cushing’s syndrome. Journal of Emergency Medicine Case Reports. 2020;11:13–16.
MLA Niafar, Mitra et al. “A Report of Recurring Pregnancy-Induced Cushing’s Syndrome”. Journal of Emergency Medicine Case Reports, vol. 11, no. 1, 2020, pp. 13-16, doi:10.33706/jemcr.633840.
Vancouver Niafar M, Bahrami A, Ghorbani F, Aghamohammadzadeh N, Sadra V, Nader Djalal N. A report of recurring pregnancy-induced Cushing’s syndrome. Journal of Emergency Medicine Case Reports. 2020;11(1):13-6.

Cited By

Endogenous hypercortisolism in pregnant women
Rossiiskii vestnik akushera-ginekologa
https://doi.org/10.17116/rosakush20222202147