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Karbon Moniksit Zehirlenmesinde Serebrovasküler Değişiklikler ve EEG Bulguları: Olgu Sunumu

Year 2010, Volume: 1 Issue: 2, 23 - 26, 01.04.2010

Senem Koruk İbrahim Tuncel Ayşe Mızrak Aylin Hengirmen Akçalı Süleyman Ganidağlı

Abstract

Karbonmonoksit (CO) zehirlenmesi, zehirlenmeye bağlı ölümlerin en
sık nedenlerindendir. CO’in, hemoglobine (Hgb) bağlanarak oluşan
karboksihemoglobinin dokularda hipoksiye yol açtığı bilinmektedir.
CO zehirlenmesinde geç nörolojik bozukluklara ileri yaşlarda daha sık
rastlanıldığı bildirilmiştir. CO zehirlenmesinde akut dönemde serebral iskemi
bulguları ve beyindeki işlev bozukluğuna bağlı EEG’de yaygın yavaş dalga
aktivitesi ile lateralizasyon gösteren diken dalgalar gösterilmiştir. Bu yazıda
CO zehirlenmesi tanısı ile acil servise müracaat eden ve yoğun bakımda
takibi yapılan 77 yaşındaki hastada ortaya çıkan nörolojik bulguların EEG
ve MR ile tespitini bildirmek istedik.

Keywords

Karbon monoksit zehirlenmesi nörolojik hasar EEG MRG

References

  • Kurel B. Carbonmonoxide intoxication and hyperbaric oxygen treatment: report of three cases. Çocuk Sağlığı ve Hastalıkları Dergisi 2005;48:164-7.
  • Choi IS. Delayed neurologic sequel in carbon monoxide intoxication. Arc Neurol. 1983;40:422-5.
  • Peterson JE, Stewart RD. Absorption and elimination of carbon monoxide by inactive young men. Arch Environ Health 1970;21:165-171.
  • Thom SR, Taber RI, Mendiguren II et al. Delayed neuropsychologic sequelae after carbon monoxoide poisoning: Prevention by treatment with hyperbaric oxygen. Ann Emerg Med. 1995;25:474-480.
  • O’Donnel P, Buxton PJ, Pitkin A, Jarvis LJ. The magnetic resonance imaging appearances of the brain in acute carbon monoxide poisoning. Clin Radiol. 2000;55:273– 280.
  • Chu KC, Jung KH, Kim HJ, Jeong SW, Kang DW, Roh JK. Diffusion-weighted MRI and 99mTc-HMPAO SPECT in delayed relapsing type of carbon monoxide poisoning: evidence of delayed cytotoxic edema. Eur Neurol. 2004;51:98-103.
  • Chung-Ping Lo, Shao-Yuan Chen et al. Brain Injury After Acute Carbon Monoxide Poisoning: Early and Late Complications. AJR. 2007;189:205-211.
  • Leon D. Carbon monoxide intoxication: An updated review. Journal of the Neurol Sci. 2007;262:122-130.
  • Neufeld MY, Swanson JW, Klas DW, et al.Localized EEG abnormalities in acute carbon monoxide poisoning. Arch Neurol. 1981;38:524-527.
  • Denays R, Makhoul E, Dachy B, et al. Electroencephalographic mapping and 99m Tc HMPAO single-photon emission computed tomography in carbon monoxide poisoning. Ann Emerg Med. 1994;24:947-952.

Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report

Year 2010, Volume: 1 Issue: 2, 23 - 26, 01.04.2010

Senem Koruk İbrahim Tuncel Ayşe Mızrak Aylin Hengirmen Akçalı Süleyman Ganidağlı

Abstract

Carbon monoxide (CO) intoxication is one of the most seen causes of death
due to intoxication. CO has affinity to hemoglobin. Hemoglobin and CO
complex carboxyhemoglobin (COHgb) causes hypoxia in tissue. In acute
phase of CO intoxication generalized slow wave activity and lateralized pike
waves could be seen on EEG. Late onset neurological deficits due to CO
intoxication were seen more in elder patients. In this report we define a case
of 77 years old age woman who was managed in intensive care unit due to
CO intoxication with unconsciousness in which the neurological defects are
shown with MRI and EEG.

Keywords

Carbon monoxide intoxication neurologic deficit EEG MRI

References

  • Kurel B. Carbonmonoxide intoxication and hyperbaric oxygen treatment: report of three cases. Çocuk Sağlığı ve Hastalıkları Dergisi 2005;48:164-7.
  • Choi IS. Delayed neurologic sequel in carbon monoxide intoxication. Arc Neurol. 1983;40:422-5.
  • Peterson JE, Stewart RD. Absorption and elimination of carbon monoxide by inactive young men. Arch Environ Health 1970;21:165-171.
  • Thom SR, Taber RI, Mendiguren II et al. Delayed neuropsychologic sequelae after carbon monoxoide poisoning: Prevention by treatment with hyperbaric oxygen. Ann Emerg Med. 1995;25:474-480.
  • O’Donnel P, Buxton PJ, Pitkin A, Jarvis LJ. The magnetic resonance imaging appearances of the brain in acute carbon monoxide poisoning. Clin Radiol. 2000;55:273– 280.
  • Chu KC, Jung KH, Kim HJ, Jeong SW, Kang DW, Roh JK. Diffusion-weighted MRI and 99mTc-HMPAO SPECT in delayed relapsing type of carbon monoxide poisoning: evidence of delayed cytotoxic edema. Eur Neurol. 2004;51:98-103.
  • Chung-Ping Lo, Shao-Yuan Chen et al. Brain Injury After Acute Carbon Monoxide Poisoning: Early and Late Complications. AJR. 2007;189:205-211.
  • Leon D. Carbon monoxide intoxication: An updated review. Journal of the Neurol Sci. 2007;262:122-130.
  • Neufeld MY, Swanson JW, Klas DW, et al.Localized EEG abnormalities in acute carbon monoxide poisoning. Arch Neurol. 1981;38:524-527.
  • Denays R, Makhoul E, Dachy B, et al. Electroencephalographic mapping and 99m Tc HMPAO single-photon emission computed tomography in carbon monoxide poisoning. Ann Emerg Med. 1994;24:947-952.
There are 10 citations in total.

Details

Other ID JA68FC25VV
Journal Section Case Report
Authors

Senem Koruk

İbrahim Tuncel This is me

Ayşe Mızrak This is me

Aylin Hengirmen Akçalı This is me

Süleyman Ganidağlı This is me

Publication Date April 1, 2010
Submission Date April 1, 2010
Published in Issue Year 2010 Volume: 1 Issue: 2

Cite

APA Koruk, S., Tuncel, İ., Mızrak, A., Akçalı, A. H., et al. (2010). Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report. Journal of Emergency Medicine Case Reports, 1(2), 23-26.
AMA Koruk S, Tuncel İ, Mızrak A, Akçalı AH, Ganidağlı S. Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report. Journal of Emergency Medicine Case Reports. April 2010;1(2):23-26.
Chicago Koruk, Senem, İbrahim Tuncel, Ayşe Mızrak, Aylin Hengirmen Akçalı, and Süleyman Ganidağlı. “Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report”. Journal of Emergency Medicine Case Reports 1, no. 2 (April 2010): 23-26.
EndNote Koruk S, Tuncel İ, Mızrak A, Akçalı AH, Ganidağlı S (April 1, 2010) Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report. Journal of Emergency Medicine Case Reports 1 2 23–26.
IEEE S. Koruk, İ. Tuncel, A. Mızrak, A. H. Akçalı, and S. Ganidağlı, “Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report”, Journal of Emergency Medicine Case Reports, vol. 1, no. 2, pp. 23–26, 2010.
ISNAD Koruk, Senem et al. “Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report”. Journal of Emergency Medicine Case Reports 1/2 (April 2010), 23-26.
JAMA Koruk S, Tuncel İ, Mızrak A, Akçalı AH, Ganidağlı S. Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report. Journal of Emergency Medicine Case Reports. 2010;1:23–26.
MLA Koruk, Senem et al. “Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report”. Journal of Emergency Medicine Case Reports, vol. 1, no. 2, 2010, pp. 23-26.
Vancouver Koruk S, Tuncel İ, Mızrak A, Akçalı AH, Ganidağlı S. Cerebrovascular Changes and EEG Findings in Carbon Monoxide Intoxication: Case Report. Journal of Emergency Medicine Case Reports. 2010;1(2):23-6.