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Marihuana suistimali ile ilişkili yineleyen inme

Year 2011, Volume: 2 Issue: 4, 33 - 35, 01.10.2011

Semih Giray Betül Gülalp , Mehmet Karataş Mehmet Nur Altınors Ufuk Can

Abstract

Giriş: Tüm dünyada en çok suistimal edilen maddelerden biridir. Cannabis
sativa bitkisinden elde edilir ve temel etkilerini delta-9-tetrahydrocannabinol
[THC] ile oluşturur. Klinik etkileri solunum sistemi,
santral sinir sistemi, psikiyatrik olarak meydana gelir ve bunlar genellikle
geçicidir. Bu rapor kronik kullanımı izleyen komplike ölümcül bir
olguyu sunmaktadır.
Olgu sunumu: 35 yaşında erkek hasta acile bilinç bozukluğu, ajitasyon
ve akut sağ hemipleji ile getirildi. Beyin tomografisinde yalnız kronik
infart vardı. Fibrinojen ve D-Dimer dışında tüm laboratuar sonuçları
normal aralıkta idi. Beyin Magnetik Rezonans Görüntüleme [MRG]
and MR Angiografi [MRA] akut orta serebral arter [OSA] infarktüsüne
bağlı lezyonu gösterdi. Ekokardiografi kalp akinezisini ve azalan ejeksiyon
fraksiyonunu açıkladı. Yatışının üçüncü günü, yakınları hastanın
uzun zamandır bir marihuana çeşidi olan esrarı kronik olarak düzenli
kullandığını açıkladılar. Tüm toksikolojik parametrelerin belirlenmesi
için örnekler laboratuvara gönderildi, ama THC tek pozitif sonuçtu.
Klinik prognoz oldukça kötüydü. Hasta yedinci gün yoğun bakımda
kaybedildi.
Sonuç: Marihuana kronik kullanımında ölümcül komplikasyonlar ile
kardiyovasküler ve serebral sistemlerde ciddi olarak zararlı olabilir.

Keywords

Esrar acil serviste inme

References

  • Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, How- land MA, Hoffman RS: Marijuana. Goldfrank’s Toxicologic Emergencies. Part D. 6th edition. Edited by Goldfrank LR. Apple- ton and Lange 1998:1121-1125.
  • Iversen L. Cannabis and the brain: Brain 2003;126:1252-1270.
  • Clough A, Conigrave K. Managing confidentiality in illicit drugs research: ethical and legal lessons from studies in remote Aborigi- nal communities. Intern Med J 2008;38:60-3.
  • Hii SW, Tam JD, Thompson BR, Naughton MT: Bullous lung dis- ease due to marijuana. Respirology 2008;13:122-7.
  • Nixon PJ. Health effects of marijuana: a review. Pac Health Dialog 2006;13:123-9.
  • Borini P, Guimaraes RC, Borini SB: Possible hepatotoxicity of chronic marijuana usage. Sao Paulo Med J 200;122:110-6.
  • Charles R, Holt S, Kirkham N: Myocardial infarction and mari- juana. Clin Toxicol 1979;14:433-8.
  • Cairns JA, Theroux P, Lewis HD. Antithrombotic agents in coro- nary artery disease. Chest 1998;114:611S-633S.
  • Finsterer J, Christian P, Wolfgang K. Occipital stroke shortly after cannabis consumption. Clin Neurol Neurosur 2004;106:305-8.
  • Alvaro LC, Iriondo I, Villaverde FJ. Sexual headache and stroke in a heavy cannabis smoker. Headache 2002;42:224-6.
  • Vaitkus PT, Barnathan ES. Embolic potential, prevention and man- agement of mural thrombus complicating anterior myocardial in- farction: a meta-analysis. J Am Coll Cardiol 1993;22:1004-9.
  • Thanvi BR, Treadwell SD. Cannabis and stroke: is there a link? Postgrad Med J 2009;85:80-3.
  • Moussouttas M. Cannabis use and cerebrovascular disease. Neu- rologist 2004;10:47-53.
  • Mateo I, Infante J, Gomez Beldarrain M, et al: Cannabis and cere- brovascular disease. Neurologia 2006;21:204.

Recurrent stroke associated with marijuana abuse

Year 2011, Volume: 2 Issue: 4, 33 - 35, 01.10.2011

Semih Giray Betül Gülalp , Mehmet Karataş Mehmet Nur Altınors Ufuk Can

Abstract

Introduction: It is one of most abused substances all over the world. It is produced from the Cannabis sativa and induces its main effects by delta-9-tetrahydrocannabinol [THC]. Clinical effects consist in respiratory, central nervous system, pshyciatric health, and these are generally transient. This report presents a complicated mortal case followed with chronic use.Case Report: A 35-year-old male patient was brought to the emergency department with unconciousness, agitation and acute right hemiplegia. There was only a chronic infarction on cerebral computerised tomography. All the laboratory results were in normal range except fibrinogen and D-dimer. Cerebral Magnetic Resonance Imaging [MRI] and MR Angiography [MRA] showed the lesion to be related to an acute middle cerebral artery [MCA] infarction. Ecocardiography revealed cardiac akinesia and a decreased ejection fraction. On the third day of admission, his relatives explained his chronic regular abuse of high dose hashish, a kind of marijuana, for along time. Samples were sent to the laboratory for identification of all toxicological parameters; however THC was the only positive result. The clinical prognosis was very poor. He had died in the intensive care unit on the seventh day.Conclusion: Marijuana can be seriously harmful to cardiovascular and cerebral systems with mortal complications in chronic use

Keywords

Hashish emergency department stroke

References

  • Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, How- land MA, Hoffman RS: Marijuana. Goldfrank’s Toxicologic Emergencies. Part D. 6th edition. Edited by Goldfrank LR. Apple- ton and Lange 1998:1121-1125.
  • Iversen L. Cannabis and the brain: Brain 2003;126:1252-1270.
  • Clough A, Conigrave K. Managing confidentiality in illicit drugs research: ethical and legal lessons from studies in remote Aborigi- nal communities. Intern Med J 2008;38:60-3.
  • Hii SW, Tam JD, Thompson BR, Naughton MT: Bullous lung dis- ease due to marijuana. Respirology 2008;13:122-7.
  • Nixon PJ. Health effects of marijuana: a review. Pac Health Dialog 2006;13:123-9.
  • Borini P, Guimaraes RC, Borini SB: Possible hepatotoxicity of chronic marijuana usage. Sao Paulo Med J 200;122:110-6.
  • Charles R, Holt S, Kirkham N: Myocardial infarction and mari- juana. Clin Toxicol 1979;14:433-8.
  • Cairns JA, Theroux P, Lewis HD. Antithrombotic agents in coro- nary artery disease. Chest 1998;114:611S-633S.
  • Finsterer J, Christian P, Wolfgang K. Occipital stroke shortly after cannabis consumption. Clin Neurol Neurosur 2004;106:305-8.
  • Alvaro LC, Iriondo I, Villaverde FJ. Sexual headache and stroke in a heavy cannabis smoker. Headache 2002;42:224-6.
  • Vaitkus PT, Barnathan ES. Embolic potential, prevention and man- agement of mural thrombus complicating anterior myocardial in- farction: a meta-analysis. J Am Coll Cardiol 1993;22:1004-9.
  • Thanvi BR, Treadwell SD. Cannabis and stroke: is there a link? Postgrad Med J 2009;85:80-3.
  • Moussouttas M. Cannabis use and cerebrovascular disease. Neu- rologist 2004;10:47-53.
  • Mateo I, Infante J, Gomez Beldarrain M, et al: Cannabis and cere- brovascular disease. Neurologia 2006;21:204.
There are 14 citations in total.

Details

Other ID JA53HP66VG
Journal Section Case Report
Authors

Semih Giray This is me

Betül Gülalp

Mehmet Karataş This is me

Mehmet Nur Altınors This is me

Ufuk Can This is me

Publication Date October 1, 2011
Submission Date October 1, 2011
Published in Issue Year 2011 Volume: 2 Issue: 4

Cite

APA Giray, S., Gülalp, B., Karataş, M., Altınors, M. N., et al. (2011). Recurrent stroke associated with marijuana abuse. Journal of Emergency Medicine Case Reports, 2(4), 33-35.
AMA Giray S, Gülalp B, Karataş M, Altınors MN, Can U. Recurrent stroke associated with marijuana abuse. Journal of Emergency Medicine Case Reports. October 2011;2(4):33-35.
Chicago Giray, Semih, Betül Gülalp, Mehmet Karataş, Mehmet Nur Altınors, and Ufuk Can. “Recurrent Stroke Associated With Marijuana Abuse”. Journal of Emergency Medicine Case Reports 2, no. 4 (October 2011): 33-35.
EndNote Giray S, Gülalp B, Karataş M, Altınors MN, Can U (October 1, 2011) Recurrent stroke associated with marijuana abuse. Journal of Emergency Medicine Case Reports 2 4 33–35.
IEEE S. Giray, B. Gülalp, M. Karataş, M. N. Altınors, and U. Can, “Recurrent stroke associated with marijuana abuse”, Journal of Emergency Medicine Case Reports, vol. 2, no. 4, pp. 33–35, 2011.
ISNAD Giray, Semih et al. “Recurrent Stroke Associated With Marijuana Abuse”. Journal of Emergency Medicine Case Reports 2/4 (October 2011), 33-35.
JAMA Giray S, Gülalp B, Karataş M, Altınors MN, Can U. Recurrent stroke associated with marijuana abuse. Journal of Emergency Medicine Case Reports. 2011;2:33–35.
MLA Giray, Semih et al. “Recurrent Stroke Associated With Marijuana Abuse”. Journal of Emergency Medicine Case Reports, vol. 2, no. 4, 2011, pp. 33-35.
Vancouver Giray S, Gülalp B, Karataş M, Altınors MN, Can U. Recurrent stroke associated with marijuana abuse. Journal of Emergency Medicine Case Reports. 2011;2(4):33-5.