Karbon Monoksit Zehirlenmesinin Neden Olduğu Görme Kaybı Için Hiperbarik Oksijen Tedavisi

Year 2013, Volume: 4 Issue: 1, 4 - 6, 01.01.2013

Tarık Ocak Mustafa Baştürk Salih Aydın Özer Kemahlı Mehmet Emre Abanoz Arif Duran

Abstract

Beyin ve kalp gibi yüksek oksijen (O2
) harcayan organlar çok kolay
bir şekilde karbon monoksit (CO) toksisitesinden etkilenirler. Beyin
dokusunda gri maddede ve özellikle globus pallidusta sıklıkla
bilateral olan iskemik lezyonlar ve nekroz en sık görülen değişikliklerdir.
Zehirlenmenin şiddetine bağlı olarak serebral, kardiyak
bulgular oluşabileceği gibi nadiren de olsa görme kusurları oluşabilir.
Görme bozuklukları genellikle komadan çıkan hastalarda görülür.
Bu sunumda CO zehirlenmesi sonucu ileri derecede görme
kaybı gelişen ve yapılan uzun süreli hiperbarik oksijen tedavisine
tam yanıt veren bir olgudan bahsettik.

Keywords

Karbon monoksit zehirlenmesi, görme kaybı, hiperbarik oksijen tedavisi

Hyperbaric Oxygen Treatment for Visual Loss Due to Carbon Monoxide Intoxication: A Case Report

Abstract

High oxygen (O2) consuming organs such as the brain and the heart are easily affected by carbon monoxide (CO) intoxication. The most frequent changes are bilateral ischemic lesions and necrosis in the grey substance of brain tissue, particularly in the globus pallidus. Depending on the severity of intoxication, cerebral and cardiac findings may occur as well as visual impairment, although rare. Visual disorders may develop in patients recovering from coma. In this case report, we present a case with severe loss of vision consequent to CO intoxication, who demonstrated a complete response to long-term hyperbaric oxygen treatment

Keywords

Carbon monoxide intoxication, visual loss, hyperbaric oxygen treatment

References

• Goldbaum LR, Orellano T, Dergal E. Mechanism of the toxic action of carbon monoxide. Ann Clin Lab Sci 1976; 6: 372-6.
• Ryter SW, Otterbein LE. Carbon monoxide in biology and medicine. Bioessays 2004; 26: 270-80. [CrossRef]
• Aksu NM, Akkaş M, Çoşkun F, Karakiliç E, Günalp M, Akküçük H, et al. Could vital signs predict carbon monoxide intoxication? J Int Med Res 2012; 40: 366-70. [CrossRef]
• Ernst A, Zibrak JD. Carbon monoxide poisoning. N Engl J Med 1998; 339: 1603-8. [CrossRef]
• Omaye ST. Metabolic modulation of carbon monoxide toxicity. Toxicol- ogy 2002; 180: 139-50. [CrossRef]
• Piantadosi CA. Carbon monoxide poisoning. Undersea Hyperb Med 2004; 31: 167-77.
• Deckel AW. Carbon monoxide poisoning and frontal lobe pathology: two case reports and a discussion of the literature. Brain Inj 1994; 8: 345-56. [CrossRef]
• Hopkins RO, Bigler ED. Pulmonary disorders. Medical Neuropsychology Tarter RE, Butters M, Beers SR (Eds) New York, Kluwer Academic 2001: 25-50. [CrossRef]
• O’Donnell P, Buxton PJ, Pitkin A, Jarvis LJ. The magnetic resonance im- aging appearances of the brain in acute carbon monoxide poisoning. Clin Radiol 2000; 55: 273-80. [CrossRef]
• Ersanli D, Yildiz S, Togrol E, Ay H, Qyrdedi T. Visual loss as a late complica- tion of carbon monoxide poisoning and its successful treatment with hyperbaric oxygen therapy. Swiss Med Wkly 2004; 134: 650-5.
• Stoller KP. Hyperbaric oxygen therapy (1.5 ATA) in treating sports related TBI/CTE: two case reports. Med Gas Res 2011; 1: 17. [CrossRef]
• Tomaszewski CA, Thom SR. Use of hyperbaric oxygen in toxicology. Emerg Med Clin North Am 1994; 12: 437-59.
• Hampson NB, Little CE. Hyperbaric treatment of patients with carbon monoxide poisoning in the United States. Undersea Hyperb Med 2005; 32: 21-6.
• Kao LW, Nanagas KA. Carbon monoxide poisoning. Emerg Med Clin North Am 2004; 22: 985-1018. [CrossRef] JAEMCR 2013; 4: 4-6