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Kardiyak Aritminin Eşlik Ettiği Hipokalemik Periyodik Paralizi Olgusu

Year 2014, Volume: 5 Issue: 1, 30 - 32, 01.01.2014

Abstract

Giriş: Hipokalemik periyodik paralizi (HPP) düzensiz aralıklarla
seyreden kas güçsüzlüğü atakları ile karakterize, hipokalemi ataklarının
eşlik ettiği bir hastalıktır. HPP’nin en sık sebebi otozomal
dominant geçişli konjenital bir hastalık olan ailesel periyodik paralizidir.
Potasyumun kas hücresi içerisine geçişi nedeniyle atak
sırasında serum potasyum düzeyi düşük fakat ataklar arasında
normaldir. Kas güçsüzlüğü atakları fazla karbonhidratlı gıda tüketimi,
emosyonel stres, soğuk, ağır egzersiz sonrası istirahatte,
glikokortikoidler, insülin ve diüretik gibi ilaç kullanımı, geçirilmiş
enfeksiyonlar ve gebelik gibi etkenler ile tetiklenebilir veya şiddetlenebilir.
Olgu Sunumu: Burada üst ve alt ekstremitelerde ani başlangıçlı
kas güçsüzlüğü ile acil servise başvuran 31 yaşında erkek hasta
sunduk. Ailesel PP tanısı konulan hastanın kan tetkikleride hipopotasemi
ve elektrokardiyografide mobitz tip I atriyoventriküler
blok saptandı.
Sonuç: Potasyum replasmanı ile düzelen paralizi ataklarının tekrarlaması,
hipopotasemi ve hipopotasemiyi açıklayacak sebep
olmadığında ailesel HPP tanısı konulur

References

  • Finsterer J. Primary periodic paralyses. Acta Neurol Scand 2008; 117: 145-58. [CrossRef]
  • Koç F, Bozdemir H, Sarıca Y. Familyal periodik paralizili bir aile. Gülhane Tıp Dergisi 2003; 45: 379-82.
  • Dikici S, Kocaman G, Şen Ş, Ercan N. Periyodik paralizi: Olgu sunumu. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 2011; 1: 21-3.
  • Wang HF, Tsai SC, Pan MS, Shiao CC. Complete heart block during po- tassium therapy in thyrotoxic periodic paralysis. J Emerg Med 2013; 44: 61-4. [CrossRef]
  • Lin SH, Yang SS, Chau T. A practical approach to genetic hypokalemia. Electrolyte Blood Press 2010; 8: 38-50. [CrossRef]
  • Ebus S, Verrips A, Ginjaar IB, Verhagen WI. Gastro-enteritis in hypokale- mic periodic paralysis: A life threatening condition. Clin Neurol Neuro- surg 2012; 114: 801-2. [CrossRef]
  • Stedwell RE, Allen KM, Binder LS. Hypokalemic paralyses: a review of the etiologies, pathophysiology, presentation, and therapy. Am J Emerg Med 1992; 10: 143-8. [CrossRef]
  • Kim H, Hwang H, Cheong HI, Park HW. Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations. Ko- rean J Pediatr 2011; 54: 473-6. [CrossRef]
  • Lin SH, Lin YF, Halperin ML. Hypokalaemia and paralysis. QJM 2001; 94: 133-9. [CrossRef]
  • Alfonzo AV, Isles C, Geddes C, Deighan C. Potassium disorders--clinical spectrum and emergency management. Resuscitation 2006; 70: 10-25. [CrossRef]

Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia

Year 2014, Volume: 5 Issue: 1, 30 - 32, 01.01.2014

Abstract

Introduction: Hypokalemic periodic paralysis (HPP) is a disease characterized by intermittent attacks of muscle weakness occurring at irregular intervals and accompanied by episodic hypokalemia. The most common cause of HPP is familial periodic paralysis, which is an autosomal dominantly inherited congenital disease. The serum potassium level is low during the attack due to the shift of potassium into muscle cells, but it is normal between attacks. Attacks of muscle weakness may be triggered or enhanced by high carbohydrate food consumption, emotional stress, cold, resting after strenuous exercise, drugs (such as glucocorticosteroids), insulin and diuretics, preceding infections, and pregnancy.Case Report: We hereby present a 31-year-old male patient admitted to emergency services who had suddenly developed muscle weakness in his upper and lower extremities. Hypopotassemia was observed on the blood test, the electrocardiography was a Mobitz type I atrioventricular block, and the patient was diagnosed with familial periodic paralysis (PP).Conclusion: Familial HPP is diagnosed if there are recurrent attacks of paralysis that are reversible with potassium replacement and hypopotassemia, without any apparent cause of hypopotassemia

References

  • Finsterer J. Primary periodic paralyses. Acta Neurol Scand 2008; 117: 145-58. [CrossRef]
  • Koç F, Bozdemir H, Sarıca Y. Familyal periodik paralizili bir aile. Gülhane Tıp Dergisi 2003; 45: 379-82.
  • Dikici S, Kocaman G, Şen Ş, Ercan N. Periyodik paralizi: Olgu sunumu. Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi 2011; 1: 21-3.
  • Wang HF, Tsai SC, Pan MS, Shiao CC. Complete heart block during po- tassium therapy in thyrotoxic periodic paralysis. J Emerg Med 2013; 44: 61-4. [CrossRef]
  • Lin SH, Yang SS, Chau T. A practical approach to genetic hypokalemia. Electrolyte Blood Press 2010; 8: 38-50. [CrossRef]
  • Ebus S, Verrips A, Ginjaar IB, Verhagen WI. Gastro-enteritis in hypokale- mic periodic paralysis: A life threatening condition. Clin Neurol Neuro- surg 2012; 114: 801-2. [CrossRef]
  • Stedwell RE, Allen KM, Binder LS. Hypokalemic paralyses: a review of the etiologies, pathophysiology, presentation, and therapy. Am J Emerg Med 1992; 10: 143-8. [CrossRef]
  • Kim H, Hwang H, Cheong HI, Park HW. Hypokalemic periodic paralysis; two different genes responsible for similar clinical manifestations. Ko- rean J Pediatr 2011; 54: 473-6. [CrossRef]
  • Lin SH, Lin YF, Halperin ML. Hypokalaemia and paralysis. QJM 2001; 94: 133-9. [CrossRef]
  • Alfonzo AV, Isles C, Geddes C, Deighan C. Potassium disorders--clinical spectrum and emergency management. Resuscitation 2006; 70: 10-25. [CrossRef]
There are 10 citations in total.

Details

Other ID JA78FN72KS
Journal Section Case Report
Authors

Yusuf Kenan Tekin This is me

Gülaçan Tekin This is me

Publication Date January 1, 2014
Submission Date January 1, 2014
Published in Issue Year 2014 Volume: 5 Issue: 1

Cite

APA Tekin, Y. K., & Tekin, G. (2014). Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia. Journal of Emergency Medicine Case Reports, 5(1), 30-32.
AMA Tekin YK, Tekin G. Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia. Journal of Emergency Medicine Case Reports. January 2014;5(1):30-32.
Chicago Tekin, Yusuf Kenan, and Gülaçan Tekin. “Hypokalemic Periodic Paralysis Case Accompanied With Cardiac Arrhythmia”. Journal of Emergency Medicine Case Reports 5, no. 1 (January 2014): 30-32.
EndNote Tekin YK, Tekin G (January 1, 2014) Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia. Journal of Emergency Medicine Case Reports 5 1 30–32.
IEEE Y. K. Tekin and G. Tekin, “Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia”, Journal of Emergency Medicine Case Reports, vol. 5, no. 1, pp. 30–32, 2014.
ISNAD Tekin, Yusuf Kenan - Tekin, Gülaçan. “Hypokalemic Periodic Paralysis Case Accompanied With Cardiac Arrhythmia”. Journal of Emergency Medicine Case Reports 5/1 (January 2014), 30-32.
JAMA Tekin YK, Tekin G. Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia. Journal of Emergency Medicine Case Reports. 2014;5:30–32.
MLA Tekin, Yusuf Kenan and Gülaçan Tekin. “Hypokalemic Periodic Paralysis Case Accompanied With Cardiac Arrhythmia”. Journal of Emergency Medicine Case Reports, vol. 5, no. 1, 2014, pp. 30-32.
Vancouver Tekin YK, Tekin G. Hypokalemic Periodic Paralysis Case Accompanied with Cardiac Arrhythmia. Journal of Emergency Medicine Case Reports. 2014;5(1):30-2.