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Diabetes Mellitusu Olan Bir Kadın Hastada Fournier Gangreni: Bir Olgu Sunumu

Year 2014, Volume: 5 Issue: 7, 206 - 208, 01.07.2014

Abstract

Giriş: Fournier gangreni özellikle kadın hastalarda nadir görülen
bir durumdur. Literatüre göre kadın hastalarda Fournier gangreni
vulvar veya Bartholin absesinin ilerlemesi veya histerektomi
ya da epizyotomi sonrası gelişebilir. Bu yazıda vulvar veya
Bartholin absesi olmayan, histerektomi veya epizyotomi öyküsü
bulunmayan Fournier gangreni olan bir kadın hastayı paylaşmayı
amaçladık.
Olgu Sunumu: 39 yaşında kadın hasta acil servise perineal
ve infrapubik bölgede, hiperemi, ödem ve ağrı şikayetleri ile
başvurdu. Hastanın Diabetes Mellitus (DM) ve tekrarlayıcı üriner
sistem enfeksiyonu öyküsü mevcuttu. Fizik muayenede mons
pubis üzerinde kötü kokulu, hiperemik ve nekrotik alanlar olduğu
görüldü. Vücut ısısı 38°C, lökosit sayısı 26,000 mm3
ve C-reaktif
protein 315mg/L olarak ölçüldü. Pelvis tomografisinde progresif
subkutanöz doku infiltrasyonu görüntüsü tespit edildi. Tüm
pelvik alanda olan, abdomene yayılan yumuşak doku içerisinde
gaz görüntüsü mevcuttu. Genel cerrahi tarafından hastaya geniş
perineal debritman uygulandı. Vankomisin ve klindamisin verildi.
20 günlük hastane yatışı sonrasında hasta sağlıklı olarak taburcu
edildi.
Sonuç: Fournier gangreni yüksek mortaliteye sahip, ciddi cerrahi
bir acildir. Geniş spektrumlu antibiyotik uygulanmasını takiben
geniş cerrahi debritman yapılması tedavinin köşe taşlarını
oluşturmaktadır. Her ne kadar Fournier gangreni çoğunlukla
erkek cinsiyetle ilişkilendirilmişse de, acil servis doktorları perineal
bölgede enfeksiyon bulgusu ile başvuran ve immun yetersizliğe
sebep olabilecek DM gibi komorbid hastalıkları olan kadın
hastalarda da Fournier gangrenini düşünmelidirler.

References

  • Sorensen MD, Krieger JN, Rivara FP, Broghammer JA, Klein MB, Mack CD, Wessells H. Fournier's Gangrene: population based epidemiology and outcomes. J Urol 2009; 181: 2120-6. [CrossRef]
  • Eke N. Fournier’s gangrene: a review of 1726 cases. Br J Surg 2000; 87: 718. [CrossRef]
  • Adams JR Jr, Mata JA, Venable DD, Culkin DJ, Bocchini JA Jr. Fournier's gangrene in children. Urology 1990; 35: 439-41. [CrossRef]
  • Ekingen G, Isken T, Agir H, Oncel S, Günlemez A. Fournier’s gangrene in childhood: a report of 3 infant patients. J Pediatr Surg 2008; 43: e39-42. [CrossRef]
  • Czymek R, Frank P, Limmer S, Schmidt A, Jungbluth T, Roblick U, et al. Fournier's gangrene: is the female gender a risk factor? Langenbecks Arch Surg 2010; 395: 173-80. [CrossRef]
  • Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS. Fournier's Gangrene: Current Practices. ISRN Surg 2012; 2012: 942437. [CrossRef]
  • Sarani B, Strong M, Pascual J, Schwab CW. Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg 2009; 208: 279-88. [CrossRef]
  • Levenson RB, Singh AK, Novelline RA. Fournier gangrene: role of imaging. Radiographics 2008; 28: 519-28. [CrossRef]
  • Kavalci C, Cevik Y, Durukan P, Temizoz O. Fournier’s gangrene. Intern Emerg Med 2009; 4: 433-4. [CrossRef]
  • Headley AJ. Necrotizing soft tissue infections: a primary care review. Am Fam Physician 2003; 68: 323-8.

Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case

Year 2014, Volume: 5 Issue: 7, 206 - 208, 01.07.2014

Abstract

Introduction: Fournier’s gangrene is relatively uncommon condition, especially in female patients. The literature suggests that Fournier’s gangrene in women may arise from vulvar or Bartholin’s gland abscesses or may result from hysterectomy or episiotomy. Here, we present a female with Fournier’s gangrene without a history of abscesses, hysterectomy, or episiotomy.Case Report: A 39-year-old woman presented to the emergency department with hyperemia, edema, and pain on the perineal area. The patient had a history of diabetes mellitus and recurrent urinary tract infections. Physical examination revealed malodorousness, hyperemia, and a gangrenous necrotic surface on the mons pubis. Body temperature was 38°C, WBC was 26,000 mm3, and C-reactive protein was 315 mg/L. Pelvic computed tomography revealed a progressive subcutaneous tissue infiltration and soft tissue gas within the whole pelvic area radiating to the abdomen. Wide perineal debridement was performed, and vancomycin and clindamycin were preferred for antibiotherapy. She was discharged healthy after 20 days of hospitalization.Conclusion: Fournier’s gangrene is a serious surgical emergency with a high mortality rate. Using broad-spectrum antibiotics and extensive surgical debridement remains the cornerstone of the therapy. Although Fournier’s gangrene is mostly attributed to the male gender, emergency physicians should also consider this disease in female patients who have comorbid diseases, like DM, and present with findings suggestive of infection in the perineal area

References

  • Sorensen MD, Krieger JN, Rivara FP, Broghammer JA, Klein MB, Mack CD, Wessells H. Fournier's Gangrene: population based epidemiology and outcomes. J Urol 2009; 181: 2120-6. [CrossRef]
  • Eke N. Fournier’s gangrene: a review of 1726 cases. Br J Surg 2000; 87: 718. [CrossRef]
  • Adams JR Jr, Mata JA, Venable DD, Culkin DJ, Bocchini JA Jr. Fournier's gangrene in children. Urology 1990; 35: 439-41. [CrossRef]
  • Ekingen G, Isken T, Agir H, Oncel S, Günlemez A. Fournier’s gangrene in childhood: a report of 3 infant patients. J Pediatr Surg 2008; 43: e39-42. [CrossRef]
  • Czymek R, Frank P, Limmer S, Schmidt A, Jungbluth T, Roblick U, et al. Fournier's gangrene: is the female gender a risk factor? Langenbecks Arch Surg 2010; 395: 173-80. [CrossRef]
  • Mallikarjuna MN, Vijayakumar A, Patil VS, Shivswamy BS. Fournier's Gangrene: Current Practices. ISRN Surg 2012; 2012: 942437. [CrossRef]
  • Sarani B, Strong M, Pascual J, Schwab CW. Necrotizing fasciitis: current concepts and review of the literature. J Am Coll Surg 2009; 208: 279-88. [CrossRef]
  • Levenson RB, Singh AK, Novelline RA. Fournier gangrene: role of imaging. Radiographics 2008; 28: 519-28. [CrossRef]
  • Kavalci C, Cevik Y, Durukan P, Temizoz O. Fournier’s gangrene. Intern Emerg Med 2009; 4: 433-4. [CrossRef]
  • Headley AJ. Necrotizing soft tissue infections: a primary care review. Am Fam Physician 2003; 68: 323-8.
There are 10 citations in total.

Details

Other ID JA26CC53AF
Journal Section Case Report
Authors

Gökhan Aksel This is me

Betül Akbuğa Özel This is me

Cemil Kavalcı This is me

Murat Muratoğlu This is me

Publication Date July 1, 2014
Submission Date July 1, 2014
Published in Issue Year 2014 Volume: 5 Issue: 7

Cite

APA Aksel, G., Özel, B. A., Kavalcı, C., Muratoğlu, M. (2014). Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case. Journal of Emergency Medicine Case Reports, 5(7), 206-208.
AMA Aksel G, Özel BA, Kavalcı C, Muratoğlu M. Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case. Journal of Emergency Medicine Case Reports. July 2014;5(7):206-208.
Chicago Aksel, Gökhan, Betül Akbuğa Özel, Cemil Kavalcı, and Murat Muratoğlu. “Fournier’s Gangrene in a Female Patient With Diabetes Mellitus: Report of a Case”. Journal of Emergency Medicine Case Reports 5, no. 7 (July 2014): 206-8.
EndNote Aksel G, Özel BA, Kavalcı C, Muratoğlu M (July 1, 2014) Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case. Journal of Emergency Medicine Case Reports 5 7 206–208.
IEEE G. Aksel, B. A. Özel, C. Kavalcı, and M. Muratoğlu, “Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case”, Journal of Emergency Medicine Case Reports, vol. 5, no. 7, pp. 206–208, 2014.
ISNAD Aksel, Gökhan et al. “Fournier’s Gangrene in a Female Patient With Diabetes Mellitus: Report of a Case”. Journal of Emergency Medicine Case Reports 5/7 (July 2014), 206-208.
JAMA Aksel G, Özel BA, Kavalcı C, Muratoğlu M. Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case. Journal of Emergency Medicine Case Reports. 2014;5:206–208.
MLA Aksel, Gökhan et al. “Fournier’s Gangrene in a Female Patient With Diabetes Mellitus: Report of a Case”. Journal of Emergency Medicine Case Reports, vol. 5, no. 7, 2014, pp. 206-8.
Vancouver Aksel G, Özel BA, Kavalcı C, Muratoğlu M. Fournier’s Gangrene in a Female Patient with Diabetes Mellitus: Report of a Case. Journal of Emergency Medicine Case Reports. 2014;5(7):206-8.