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Düşük Molekül Ağırlıklı Heparin Tedavisinin Nadir Komplikasyonu: Mesane Hematomu

Year 2014, Volume: 5 Issue: 9, 232 - 234, 01.09.2014

Abstract

Introduction: Low-molecular-weight heparin is one of the most preferred agents used in the prevention and treatment of thromboembolic disorders.   Case Report: An 85-year-old female patient was admitted for 3 days wıth ongoing and growing vaginal bleeding. Bladder hematoma and postrenal acute renal failure, rare complications of low-molecular-weight heparins, are presented in this case.   Conclusion: Patients who have complaints about vaginal bleeding or hematuria should be questioned about a detailed history and the use of low-molecular-weight heparin. Low-molecular-weight heparin in rare cases may lead to bleeding, and postrenal acute renal failure should be kept in mind.

References

  • Gould MK, Dembitzer AD, Doyle RL, Hastie TJ, Garber AM. Low-molecular- weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A metaanalysis of randomized, controlled trials. Ann Intern Med 1999; 130: 800-9. [CrossRef]
  • Weitz JI. Low-molecular-weight heparins. N Engl J Med 1997; 337: 688-98. [CrossRef]
  • Lensing AW, Prins MH, Davidson BL, Hirsh J. Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis. Arch Intern Med 1995; 155: 601-7. [CrossRef]
  • Siragusa S, Cosmi B, Piovella F, Hirsh J, Ginsberg JS. Low-molecular weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta- analysis. Am J Med 1996; 100: 269-77. [CrossRef]
  • The Columbus Investigators. Low-molecular-weight heparin in the treatment of patients with venous thromboembolism. N Eng J Med 1997; 337: 657-62. [CrossRef]
  • Spinler SA, Nawarskas JJ. Low-molecular weight heparins for acute coronary syndromes. Ann Pharmacother 1998; 32: 103-10. [CrossRef]
  • Ji H, Li SP, Cheng X, Cheng HR, Ng TB, Li P, Li NS. Antithrombotic effects of low-molecular-weight heparin calcium (LMWH-Ca) in experimental models. Gen Pharmocol 1999; 33: 207-11. [CrossRef]
  • Menzin J, Richner R, Huse D, Colditz GA, Oster G. Prevention of deep-vein thrombosis following total hip replacement surgery with enoxaparin versus unfractionated heparin: a pharmacoeconomic evaluation. Ann Pharmacother 1994; 28: 271-5.
  • Deep K, Jigajinni MV, McLean AN, Fraser MH. Prophylaxis of thromboembolism in spinal injuries-results of enoxaparin used in 276 patients. Spinal Cord 2001; 39: 88-91. [CrossRef]
  • Cardiovascular Disease Educational and Research Trust; Cyprus Cardiovascular Disease Educational and Research Trust; European Venous Forum; International Surgical Thrombosis Forum; International Union of Angiology; Union Internationale de Phlébologie. Prevention and treatment of venous thromboembolism-International Consensus Statement (ICS). Guidelines according to scientific evidence. Int Angiol 2006; 25: 101-61.

A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma

Year 2014, Volume: 5 Issue: 9, 232 - 234, 01.09.2014

Abstract

Introduction: Low-molecular-weight heparin is one of the most preferred agents used in the prevention and treatment of thromboembolic disorders.Case Report: An 85-year-old female patient was admitted for 3 days wıth ongoing and growing vaginal bleeding. Bladder hematoma and postrenal acute renal failure, rare complications of low-molecular-weight heparins, are presented in this case.Conclusion: Patients who have complaints about vaginal bleeding or hematuria should be questioned about a detailed history and the use of low-molecular-weight heparin. Lowmolecular-weight heparin in rare cases may lead to bleeding, and postrenal acute renal failure should be kept in mind

References

  • Gould MK, Dembitzer AD, Doyle RL, Hastie TJ, Garber AM. Low-molecular- weight heparins compared with unfractionated heparin for treatment of acute deep venous thrombosis. A metaanalysis of randomized, controlled trials. Ann Intern Med 1999; 130: 800-9. [CrossRef]
  • Weitz JI. Low-molecular-weight heparins. N Engl J Med 1997; 337: 688-98. [CrossRef]
  • Lensing AW, Prins MH, Davidson BL, Hirsh J. Treatment of deep venous thrombosis with low-molecular-weight heparins. A meta-analysis. Arch Intern Med 1995; 155: 601-7. [CrossRef]
  • Siragusa S, Cosmi B, Piovella F, Hirsh J, Ginsberg JS. Low-molecular weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: results of a meta- analysis. Am J Med 1996; 100: 269-77. [CrossRef]
  • The Columbus Investigators. Low-molecular-weight heparin in the treatment of patients with venous thromboembolism. N Eng J Med 1997; 337: 657-62. [CrossRef]
  • Spinler SA, Nawarskas JJ. Low-molecular weight heparins for acute coronary syndromes. Ann Pharmacother 1998; 32: 103-10. [CrossRef]
  • Ji H, Li SP, Cheng X, Cheng HR, Ng TB, Li P, Li NS. Antithrombotic effects of low-molecular-weight heparin calcium (LMWH-Ca) in experimental models. Gen Pharmocol 1999; 33: 207-11. [CrossRef]
  • Menzin J, Richner R, Huse D, Colditz GA, Oster G. Prevention of deep-vein thrombosis following total hip replacement surgery with enoxaparin versus unfractionated heparin: a pharmacoeconomic evaluation. Ann Pharmacother 1994; 28: 271-5.
  • Deep K, Jigajinni MV, McLean AN, Fraser MH. Prophylaxis of thromboembolism in spinal injuries-results of enoxaparin used in 276 patients. Spinal Cord 2001; 39: 88-91. [CrossRef]
  • Cardiovascular Disease Educational and Research Trust; Cyprus Cardiovascular Disease Educational and Research Trust; European Venous Forum; International Surgical Thrombosis Forum; International Union of Angiology; Union Internationale de Phlébologie. Prevention and treatment of venous thromboembolism-International Consensus Statement (ICS). Guidelines according to scientific evidence. Int Angiol 2006; 25: 101-61.
There are 10 citations in total.

Details

Other ID JA68MA58GM
Journal Section Case Report
Authors

Birdal Güllüpınar This is me

Publication Date September 1, 2014
Submission Date September 1, 2014
Published in Issue Year 2014 Volume: 5 Issue: 9

Cite

APA Güllüpınar, B. (2014). A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma. Journal of Emergency Medicine Case Reports, 5(9), 232-234.
AMA Güllüpınar B. A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma. Journal of Emergency Medicine Case Reports. September 2014;5(9):232-234.
Chicago Güllüpınar, Birdal. “A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma”. Journal of Emergency Medicine Case Reports 5, no. 9 (September 2014): 232-34.
EndNote Güllüpınar B (September 1, 2014) A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma. Journal of Emergency Medicine Case Reports 5 9 232–234.
IEEE B. Güllüpınar, “A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma”, Journal of Emergency Medicine Case Reports, vol. 5, no. 9, pp. 232–234, 2014.
ISNAD Güllüpınar, Birdal. “A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma”. Journal of Emergency Medicine Case Reports 5/9 (September 2014), 232-234.
JAMA Güllüpınar B. A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma. Journal of Emergency Medicine Case Reports. 2014;5:232–234.
MLA Güllüpınar, Birdal. “A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma”. Journal of Emergency Medicine Case Reports, vol. 5, no. 9, 2014, pp. 232-4.
Vancouver Güllüpınar B. A Rare Complication of Low-Molecular-Weight Heparin Therapy: Bladder Hematoma. Journal of Emergency Medicine Case Reports. 2014;5(9):232-4.