Melena Associated with Ganoderma lucidum: A Case Report

Demet Acar; Mustafa Gülpembe; Nazire Belgin Akıllı; Saniye Göknil Çalık; Ramazan Köylü; Yahya Kemal Günaydın; Başar Cander

Ganoderma Lucıdum İle İlişkili Melena: Vaka Sunumu

Year 2015, Volume: 6 Issue: 1, 7 - 9, 01.01.2015

Demet Acar Mustafa Gülpembe Nazire Belgin Akıllı Saniye Göknil Çalık Ramazan Köylü Yahya Kemal Günaydın Başar Cander

Abstract

Giriş: Melena acil servis hastaları arasında görülen hayatı tehdit
edebilecek bir bulgudur.
Olgu Sunumu: Biz burada, önceden bilinen herhangi bir mide
şikayeti olmayan genç bir erkek hastada Ganoderma Lucidum
kullanımı ile indüklenen bir melena olgusu sunacağız.
Sonuç: G. lucidum'un bazı toksik etkileri bildirilmiştir ancak
bildiğimiz kadarıyla, bu vaka bildirilen G. lucidum ile ilişkili ilk üst
gastrointestinal sistem kanamasıdır.

Keywords

G. lucidum, melena, mantar

References

Pericleous M, Murray C, Hamilton M, Epstein O, Negus R, et al. Using an ‘action set’ for the management of acute upper gastrointestinal bleed- ing. Therap Adv Gastroenterol 2013; 6: 426-37. [CrossRef]
Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS. Ganoderma lu- cidum: a potent pharmacological macrofungus. Curr Pharm Biotechnol 2009; 10: 717-42. [CrossRef]
Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev 2012; 6: CD007731.
Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990; 10: 240-3. [CrossRef]
Su C, Shiao M, Wang C. Potentiation of ganodermic acid S on prosta- glandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res 2000; 99: 135-45. [CrossRef]
Kwok Y, Ng KF, Li CC, Lam CC, Man RY. A prospective, randomized, dou- ble-blind, placebo-controlled study of the platelet and global hemo- static effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005; 101: 423-6. [CrossRef]
Levitan D, Macy JI, Weissman J. Mechanism of gastrointestinal hemor- rhage in a case of mushroom poisoning by Chlorophyllum molybdites. Toxicon 1981; 19: 179-80. [CrossRef]
Gao Y, Zhou S, Wen J, Huang M, Xu A. Mechanism of the antiulcero- genic effect of Ganoderma lucidum polysaccharides on indomethacin- induced lesions in the rat. Life Sci 2002; 72: 731-45. [CrossRef]
Gao Y, Tang W, Gao H, Chan E, Lan J, Zhou S. Ganoderma lucidum poly- saccharide fractions accelerate healing of acetic acid-induced ulcers in rats. J Med Food 2004; 7: 417-21. [CrossRef]
Gill SK, Rieder MJ. Toxicity of a traditional Chinese medicine, Ganoder- ma lucidum, in children with cancer. Can J Clin Pharmacol 2008; 15: e275-85.

Melena Associated with Ganoderma lucidum: A Case Report

Year 2015, Volume: 6 Issue: 1, 7 - 9, 01.01.2015

Demet Acar Mustafa Gülpembe Nazire Belgin Akıllı Saniye Göknil Çalık Ramazan Köylü Yahya Kemal Günaydın Başar Cander

Abstract

Introduction: Melena is a life-threatening complaint of patients presenting to the emergency department.Case Report: Herein we present a case of Ganoderma luciduminduced melena in a young man who did not have any symptoms of gastrointestinal disease before. Conclusion: Some toxic effects of G. lucidum have been reported previously. However, to the best of our knowledge, this is the first case report of upper gastrointestinal bleeding associated with G. lucidum

Keywords

G. lucidum, melena, mushroom

References

Pericleous M, Murray C, Hamilton M, Epstein O, Negus R, et al. Using an ‘action set’ for the management of acute upper gastrointestinal bleed- ing. Therap Adv Gastroenterol 2013; 6: 426-37. [CrossRef]
Sanodiya BS, Thakur GS, Baghel RK, Prasad GB, Bisen PS. Ganoderma lu- cidum: a potent pharmacological macrofungus. Curr Pharm Biotechnol 2009; 10: 717-42. [CrossRef]
Jin X, Ruiz Beguerie J, Sze DM, Chan GC. Ganoderma lucidum (Reishi mushroom) for cancer treatment. Cochrane Database Syst Rev 2012; 6: CD007731.
Tao J, Feng KY. Experimental and clinical studies on inhibitory effect of ganoderma lucidum on platelet aggregation. J Tongji Med Univ 1990; 10: 240-3. [CrossRef]
Su C, Shiao M, Wang C. Potentiation of ganodermic acid S on prosta- glandin E(1)-induced cyclic AMP elevation in human platelets. Thromb Res 2000; 99: 135-45. [CrossRef]
Kwok Y, Ng KF, Li CC, Lam CC, Man RY. A prospective, randomized, dou- ble-blind, placebo-controlled study of the platelet and global hemo- static effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. Anesth Analg 2005; 101: 423-6. [CrossRef]
Levitan D, Macy JI, Weissman J. Mechanism of gastrointestinal hemor- rhage in a case of mushroom poisoning by Chlorophyllum molybdites. Toxicon 1981; 19: 179-80. [CrossRef]
Gao Y, Zhou S, Wen J, Huang M, Xu A. Mechanism of the antiulcero- genic effect of Ganoderma lucidum polysaccharides on indomethacin- induced lesions in the rat. Life Sci 2002; 72: 731-45. [CrossRef]
Gao Y, Tang W, Gao H, Chan E, Lan J, Zhou S. Ganoderma lucidum poly- saccharide fractions accelerate healing of acetic acid-induced ulcers in rats. J Med Food 2004; 7: 417-21. [CrossRef]
Gill SK, Rieder MJ. Toxicity of a traditional Chinese medicine, Ganoder- ma lucidum, in children with cancer. Can J Clin Pharmacol 2008; 15: e275-85.

There are 10 citations in total.

Details

Other ID	JA62CV65VJ
Journal Section	Research Article
Authors	Demet Acar This is me Mustafa Gülpembe This is me Nazire Belgin Akıllı This is me Saniye Göknil Çalık This is me Ramazan Köylü This is me Yahya Kemal Günaydın This is me Başar Cander This is me
Publication Date	January 1, 2015
Submission Date	January 1, 2015
Published in Issue	Year 2015 Volume: 6 Issue: 1

Cite

APA	Acar, D., Gülpembe, M., Akıllı, N. B., Çalık, S. G., et al. (2015). Melena Associated with Ganoderma lucidum: A Case Report. Journal of Emergency Medicine Case Reports, 6(1), 7-9.
AMA	Acar D, Gülpembe M, Akıllı NB, Çalık SG, Köylü R, Günaydın YK, Cander B. Melena Associated with Ganoderma lucidum: A Case Report. Journal of Emergency Medicine Case Reports. January 2015;6(1):7-9.
Chicago	Acar, Demet, Mustafa Gülpembe, Nazire Belgin Akıllı, Saniye Göknil Çalık, Ramazan Köylü, Yahya Kemal Günaydın, and Başar Cander. “Melena Associated With Ganoderma Lucidum: A Case Report”. Journal of Emergency Medicine Case Reports 6, no. 1 (January 2015): 7-9.
EndNote	Acar D, Gülpembe M, Akıllı NB, Çalık SG, Köylü R, Günaydın YK, Cander B (January 1, 2015) Melena Associated with Ganoderma lucidum: A Case Report. Journal of Emergency Medicine Case Reports 6 1 7–9.
IEEE	D. Acar, “Melena Associated with Ganoderma lucidum: A Case Report”, Journal of Emergency Medicine Case Reports, vol. 6, no. 1, pp. 7–9, 2015.
ISNAD	Acar, Demet et al. “Melena Associated With Ganoderma Lucidum: A Case Report”. Journal of Emergency Medicine Case Reports 6/1 (January 2015), 7-9.
JAMA	Acar D, Gülpembe M, Akıllı NB, Çalık SG, Köylü R, Günaydın YK, Cander B. Melena Associated with Ganoderma lucidum: A Case Report. Journal of Emergency Medicine Case Reports. 2015;6:7–9.
MLA	Acar, Demet et al. “Melena Associated With Ganoderma Lucidum: A Case Report”. Journal of Emergency Medicine Case Reports, vol. 6, no. 1, 2015, pp. 7-9.
Vancouver	Acar D, Gülpembe M, Akıllı NB, Çalık SG, Köylü R, Günaydın YK, Cander B. Melena Associated with Ganoderma lucidum: A Case Report. Journal of Emergency Medicine Case Reports. 2015;6(1):7-9.