The Effectiveness of Hemodialysis in case of Intoxication with Pregabalin

Year 2019, Volume: 10 Issue: 4, 112 - 114, 01.10.2019

Metin Ocak , Cahit Uçar

https://doi.org/10.33706/jemcr.535561

Cited By: 2

Abstract

Although it was originally
developed for the treatment of epilepsy, pregabalin has also been used
frequently in the management of neuropathic pain and anxiety disorders
recently. Owing to its widespread use in this regard, number of the cases
reported with regard to both its side-effects and overdose has been escalating
dramatically. More specifically, facial rash, dizziness, drowsiness, peripheral
edema and weigh gain, hyponatremia and increase in systolic dysfunction
especially in the elderly, hepatotoxicity and transient encephalopathy were
reported with increasing incidence in the literature. We hereby reported a case
of seizure and metabolic acidosis incited by pregabalin overdose, and our aim
is to constitute an appeal for the fact that implementation of hemodialysis is
a rapid and effective method in the treatment of seizure and metabolic acidosis
in case of pregabalin intoxication. 

Keywords

Pregabalin Intoxication, Hemodialysis, Generalized tonic-clonic seizure, Metabolic Acidosis

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