Research Article
BibTex RIS Cite

Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2

Year 2021, Volume: 33 Issue: 1, 116 - 121, 30.01.2021

Mustafa Sengor

https://doi.org/10.7240/jeps.771433
Cited By: 1

Abstract

Composites of calcinated bovine bone derived hydroxyapatite (BHA) doped 1 and 2 wt% MgF2 were prepared by a sintering process. Microstructure and crystallographic analyses along with measurements of density, compression strength, and microhardness were carried out in the produced samples. The experimental results indicated a beneficial effect of MgF2 in the matrix of BHA reflected in the significant increase of compression strength and microhardness up to 143 MPa and 313 HV, respectively, achieved after sintering at 1300 0C for 2% MgF2 addition. The presence of MgF2 reduced the onset of sintering towards lower temperatures (i.e. 1100 0C) and increased the stability of hydroxyapatite towards transformation to TCP at 1300 0C. The influence of Mg2+ and F- ions in the lattice of hydroxyapatite is discussed.

Keywords

bovine hydroxyapatite MgF2 Sintering Microstructure

References

  • 1] Oktar FN, Yetmez M, Agathopoulos S, Lopez Goerne TM, Goller G, Peker I and et al., J Mater Sci: Mater in Med 2006;17:1161-71.
  • [2] Bertoni E, Bigi A, Cojazzi G, Gandolfi M, Panzavolta S, Roveri N, J Inorg Biochem 1998; 72:29-35.
  • [3] Ni S, Chou L, Chang J, Ceram Int 2007;33:83-8.
  • [4] Joschek S, Nies B, Krotz R, Göpferich A, Biomater 2000;21:1645-58.
  • [5] Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y and et al., Biomater 2003;24:4913-20.
  • [6] Gunduz O, Karacayli U, Salman S, Valerio P, Goes AM, Agathopoulos S and et al., Int. J Artif Organs 2008;31:611-2.
  • [7] Cai Y, Zhang S, Zeng X, Wang Y, Qian M, Weng W, Thin Solid Films 2009;517: 5347-51.
  • [8] Oktar FN, Agathopoulos S, Ozyegin LS, Gunduz O, Demirkol N, Bozkurt Y and et al., J Mater Sci: Mater in Med 2007;18:2137-43.
  • [9] Kim SK, Lee JH, Kim YT, Riu DH, Jung SJ, Lee YJ and et al., Biomater 2003;24: 1389-98.
  • [10] Kim S-J, Bang H-G, Song J-H, Park S-Y, Ceram Int 2009;35:1647-50.
  • [11] Evis Z, Usta M, Kutbay I, J Eur Ceram Soc 2009;29:621-8.
  • [12] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • 1] Oktar FN, Yetmez M, Agathopoulos S, Lopez Goerne TM, Goller G, Peker I and et al., J Mater Sci: Mater in Med 2006;17:1161-71.
  • [2] Bertoni E, Bigi A, Cojazzi G, Gandolfi M, Panzavolta S, Roveri N, J Inorg Biochem 1998; 72:29-35.
  • [3] Ni S, Chou L, Chang J, Ceram Int 2007;33:83-8.
  • [4] Joschek S, Nies B, Krotz R, Göpferich A, Biomater 2000;21:1645-58.
  • [5] Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y and et al., Biomater 2003;24:4913-20.
  • [6] Gunduz O, Karacayli U, Salman S, Valerio P, Goes AM, Agathopoulos S and et al., Int. J Artif Organs 2008;31:611-2.
  • [7] Cai Y, Zhang S, Zeng X, Wang Y, Qian M, Weng W, Thin Solid Films 2009;517: 5347-51.
  • [8] Oktar FN, Agathopoulos S, Ozyegin LS, Gunduz O, Demirkol N, Bozkurt Y and et al., J Mater Sci: Mater in Med 2007;18:2137-43.
  • [9] Kim SK, Lee JH, Kim YT, Riu DH, Jung SJ, Lee YJ and et al., Biomater 2003;24: 1389-98.
  • [10] Kim S-J, Bang H-G, Song J-H, Park S-Y, Ceram Int 2009;35:1647-50.
  • [11] Evis Z, Usta M, Kutbay I, J Eur Ceram Soc 2009;29:621-8.
  • [12] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • [13] Evis Z, "Reactions in hydroxylapatite–zirconia composites," Ceram Int 2007;33:987-91 .
  • [14] F.N. Oktar, Ph.D. Thesis: ''Characterization of processed tooth hydroxyapatite and bioglass for potential applications in dentistry'', (1999) Bogazici University.
  • [15] Oktar FN, Kesenci K, Piskin E, Artif Cell Blood Subs Immob Biotechn 1999;27:367-79.
  • [16] Carvalho AL, Faria PEP, Grisi MFM, Souza SLS, Taba M, Jr Palioto DB and et al., J Oral Implant 2007;33:267-76.
  • [17] Gunduz O, Daglilar S, Salman S, Ekren N, Agathopoulos S, Oktar FN, J Comp Mater 2008;42:1281-7.
  • [18] Gunduz O, Ahmad Z, Ekren N, Agathopoulos S, Salman S, Oktar FN, J Therm Comp Mater 2009;22:407-19.
  • [19] Salman S, Gunduz O, Yilmaz S, Öveçoğlu L, Snyder RL, Agathopoulos S, Oktar FN, Ceram Int 2009;35:2965-71.
  • [20] Gunduz O, Erkan EM, Daglilar S, Salman S, Agathopoulos S, Oktar FN, J Mater Sci 2008;43:2536-40.
  • [21] Ozyegin LS, Oktar FN, Goller G, Kayali ES, Yazici T, Mater Let 2004;58:2605-9.
  • [22] British Standards 7253: Part 2: 1990, ISO 6474-1981.
  • [23] Ozyegin LS, Oktar FN, Agathopoulos S, Salman S, Bozkurt Y, Eruslu N, Key Eng Mater 2007;330-332:43-6.
  • [24] Goller G, Oktar FN, Agathopoulos S, Tulyaganov DU, Ferreira JMF, Kayali ES and et al., J Sol-Gel Sci Techn 2006;37:111-5.
  • [25] Goren S, Gokbayrak H, Altintas S, Key Eng Mater 2004;264-268:1949-52.
  • [26] Gokbayrak H, Production of hydroxyapatite ceramics, M.Sc. Thesis, Bogazici University, 1996.
  • [27] Goller G, Oktar FN, Mater Lett 2002;56:142-7.
  • [28] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • [29] Oktar FN, "Hydroxyapatite–TiO2 composites" Mater Lett 2006;60:2207-10 .
  • [30] Salman S, Oktar FN, Gunduz O, Agathopoulos S, Öveçoğlu ML, Kayalı ES, Key Eng Mater 2007;330-332:189-92.
  • [31] Erkmen ZE, Genc Y, Oktar FN, J Am Ceram Soc 2007;90:2885-92.
  • [32] Ooi CY, Hamdi M, Ramesh S, Ceram Int 2007;33:1171-7.
  • [33] Goller G, Oktar FN, Ozyegin LS, Kayali ES, Demirkesen E, Mater Lett 2004;58: 2599-604.
  • [34] Demirkol N, Karacayli U, Gunduz O, Salman S, Agathopoulos S, Kayali ES and et al., A novel biomaterial: Chicken hydroxyapatite (CHA). Euromat 2009, European Congress and Exhibition on Advanced Materials and Processes. 7-10 September, Glaskow, UK.
  • [35] Unpublished data by Gunduz O, Karacali U, Demirkol N, Oktar FN, Enamel and dentine derived HA from bovine teeth, enamel and dentine derived HA from sheep teeth.
  • [36] Goller G, Oktar FN, Key Eng Mater 2002;206-212:1615-20.
  • [37] Oktar FN, "Microstructure and mechanical properties of sintered enamel hydroxyapatite", Ceram Int 2007;33:1309-14.
  • [38] Oktar FN, Goller G, "Sintering effects on mechanical properties of glass-reinforced hydroxyapatite composites", Ceram Int 2002;28:617-21.
  • [39] Goller G, Demirkıran H, Oktar FN, Demirkesen E, Ceram Int 2003;29:721-4.
  • [40] Goller G, Oktar FN, Toykan D, Kayali ES, Key Eng Mater 2003;240-242:619-22.
  • [41] Kurkcu M, Benlidayi ME, Ozsoy S, Ozyegin LS, Oktar FN, Kurtoglu C, J. Mater. Sci Mater Med 2008;19:59-65.
  • [42] Daglilar S, Erkan ME, Gunduz O, Ozyegin LS, Salman S, Agathopoulos S and et al., Mater. Lett. 2007;61:2295-98.
  • [43] Lemos AF, Rocha JHG, Quaresma SSF, Kannan S, Oktar FN, Agathopoulos S and et al., J Eur Ceram Soc 2006;26:3639-46.
  • [44] Tuyel U, Oner ET, Ozyegin S, Oktar FN, J Biotech 2007;131S:S65-S66.
  • [45] Rocha JHG, Lemos AF, Agathopoulos S, Valério P, Kannan S, Oktar FN and et al., Bone 2005;37:850-7.
  • [46] Karacayli U, Gunduz O, Salman S, Ozyegin LS, Agathopoulos S, Oktar FN, Effect of sintering temperature on mechanical properties and microstructure of sheep-bone derived hydroxyapatite (SHA). The 13th International Conference on Biomedical Engineering, Singapoure, 3-6 December 2008. Proceedings pp. 103-4.
  • [47] Gunduz O, Karacayli U, Salman S, Kayali ES, Sengil AZ, Agathopoulos S and et al., A Novel Natural Hydroxyapatite: Sheep Hydroxyapatite. 22nd International Symposium on Ceramics in Medicine “Bioceramics-22”, Daegu, Korea, 26-29 October, 2009. Proceedings pp. 483-6.
  • [48] Kannan S, Goetz-Neunhoeffer F, Neubauer J, Ferreira JMF, J Am Ceram Soc 2008; 91:1-12.

Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2

Year 2021, Volume: 33 Issue: 1, 116 - 121, 30.01.2021

Mustafa Sengor

https://doi.org/10.7240/jeps.771433
Cited By: 1

Abstract

Composites of calcinated bovine bone derived hydroxyapatite (BHA) doped 1 and 2 wt% MgF2 were prepared by a sintering process. Microstructure and crystallographic analyses along with measurements of density, compression strength, and microhardness were carried out in the produced samples. The experimental results indicated a beneficial effect of MgF2 in the matrix of BHA reflected in the significant increase of compression strength and microhardness up to 143 MPa and 313 HV, respectively, achieved after sintering at 1300 0C for 2% MgF2 addition. The presence of MgF2 reduced the onset of sintering towards lower temperatures (i.e. 1100 0C) and increased the stability of hydroxyapatite towards transformation to TCP at 1300 0C. The influence of Mg2+ and F- ions in the lattice of hydroxyapatite is discussed.

Keywords

hidroksiapatit MgF2 mikroyapı

References

  • 1] Oktar FN, Yetmez M, Agathopoulos S, Lopez Goerne TM, Goller G, Peker I and et al., J Mater Sci: Mater in Med 2006;17:1161-71.
  • [2] Bertoni E, Bigi A, Cojazzi G, Gandolfi M, Panzavolta S, Roveri N, J Inorg Biochem 1998; 72:29-35.
  • [3] Ni S, Chou L, Chang J, Ceram Int 2007;33:83-8.
  • [4] Joschek S, Nies B, Krotz R, Göpferich A, Biomater 2000;21:1645-58.
  • [5] Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y and et al., Biomater 2003;24:4913-20.
  • [6] Gunduz O, Karacayli U, Salman S, Valerio P, Goes AM, Agathopoulos S and et al., Int. J Artif Organs 2008;31:611-2.
  • [7] Cai Y, Zhang S, Zeng X, Wang Y, Qian M, Weng W, Thin Solid Films 2009;517: 5347-51.
  • [8] Oktar FN, Agathopoulos S, Ozyegin LS, Gunduz O, Demirkol N, Bozkurt Y and et al., J Mater Sci: Mater in Med 2007;18:2137-43.
  • [9] Kim SK, Lee JH, Kim YT, Riu DH, Jung SJ, Lee YJ and et al., Biomater 2003;24: 1389-98.
  • [10] Kim S-J, Bang H-G, Song J-H, Park S-Y, Ceram Int 2009;35:1647-50.
  • [11] Evis Z, Usta M, Kutbay I, J Eur Ceram Soc 2009;29:621-8.
  • [12] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • 1] Oktar FN, Yetmez M, Agathopoulos S, Lopez Goerne TM, Goller G, Peker I and et al., J Mater Sci: Mater in Med 2006;17:1161-71.
  • [2] Bertoni E, Bigi A, Cojazzi G, Gandolfi M, Panzavolta S, Roveri N, J Inorg Biochem 1998; 72:29-35.
  • [3] Ni S, Chou L, Chang J, Ceram Int 2007;33:83-8.
  • [4] Joschek S, Nies B, Krotz R, Göpferich A, Biomater 2000;21:1645-58.
  • [5] Yamasaki Y, Yoshida Y, Okazaki M, Shimazu A, Kubo T, Akagawa Y and et al., Biomater 2003;24:4913-20.
  • [6] Gunduz O, Karacayli U, Salman S, Valerio P, Goes AM, Agathopoulos S and et al., Int. J Artif Organs 2008;31:611-2.
  • [7] Cai Y, Zhang S, Zeng X, Wang Y, Qian M, Weng W, Thin Solid Films 2009;517: 5347-51.
  • [8] Oktar FN, Agathopoulos S, Ozyegin LS, Gunduz O, Demirkol N, Bozkurt Y and et al., J Mater Sci: Mater in Med 2007;18:2137-43.
  • [9] Kim SK, Lee JH, Kim YT, Riu DH, Jung SJ, Lee YJ and et al., Biomater 2003;24: 1389-98.
  • [10] Kim S-J, Bang H-G, Song J-H, Park S-Y, Ceram Int 2009;35:1647-50.
  • [11] Evis Z, Usta M, Kutbay I, J Eur Ceram Soc 2009;29:621-8.
  • [12] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • [13] Evis Z, "Reactions in hydroxylapatite–zirconia composites," Ceram Int 2007;33:987-91 .
  • [14] F.N. Oktar, Ph.D. Thesis: ''Characterization of processed tooth hydroxyapatite and bioglass for potential applications in dentistry'', (1999) Bogazici University.
  • [15] Oktar FN, Kesenci K, Piskin E, Artif Cell Blood Subs Immob Biotechn 1999;27:367-79.
  • [16] Carvalho AL, Faria PEP, Grisi MFM, Souza SLS, Taba M, Jr Palioto DB and et al., J Oral Implant 2007;33:267-76.
  • [17] Gunduz O, Daglilar S, Salman S, Ekren N, Agathopoulos S, Oktar FN, J Comp Mater 2008;42:1281-7.
  • [18] Gunduz O, Ahmad Z, Ekren N, Agathopoulos S, Salman S, Oktar FN, J Therm Comp Mater 2009;22:407-19.
  • [19] Salman S, Gunduz O, Yilmaz S, Öveçoğlu L, Snyder RL, Agathopoulos S, Oktar FN, Ceram Int 2009;35:2965-71.
  • [20] Gunduz O, Erkan EM, Daglilar S, Salman S, Agathopoulos S, Oktar FN, J Mater Sci 2008;43:2536-40.
  • [21] Ozyegin LS, Oktar FN, Goller G, Kayali ES, Yazici T, Mater Let 2004;58:2605-9.
  • [22] British Standards 7253: Part 2: 1990, ISO 6474-1981.
  • [23] Ozyegin LS, Oktar FN, Agathopoulos S, Salman S, Bozkurt Y, Eruslu N, Key Eng Mater 2007;330-332:43-6.
  • [24] Goller G, Oktar FN, Agathopoulos S, Tulyaganov DU, Ferreira JMF, Kayali ES and et al., J Sol-Gel Sci Techn 2006;37:111-5.
  • [25] Goren S, Gokbayrak H, Altintas S, Key Eng Mater 2004;264-268:1949-52.
  • [26] Gokbayrak H, Production of hydroxyapatite ceramics, M.Sc. Thesis, Bogazici University, 1996.
  • [27] Goller G, Oktar FN, Mater Lett 2002;56:142-7.
  • [28] Evis Z, Usta M, Kutbay I, Mater Chem Phys 2008;110:68-75.
  • [29] Oktar FN, "Hydroxyapatite–TiO2 composites" Mater Lett 2006;60:2207-10 .
  • [30] Salman S, Oktar FN, Gunduz O, Agathopoulos S, Öveçoğlu ML, Kayalı ES, Key Eng Mater 2007;330-332:189-92.
  • [31] Erkmen ZE, Genc Y, Oktar FN, J Am Ceram Soc 2007;90:2885-92.
  • [32] Ooi CY, Hamdi M, Ramesh S, Ceram Int 2007;33:1171-7.
  • [33] Goller G, Oktar FN, Ozyegin LS, Kayali ES, Demirkesen E, Mater Lett 2004;58: 2599-604.
  • [34] Demirkol N, Karacayli U, Gunduz O, Salman S, Agathopoulos S, Kayali ES and et al., A novel biomaterial: Chicken hydroxyapatite (CHA). Euromat 2009, European Congress and Exhibition on Advanced Materials and Processes. 7-10 September, Glaskow, UK.
  • [35] Unpublished data by Gunduz O, Karacali U, Demirkol N, Oktar FN, Enamel and dentine derived HA from bovine teeth, enamel and dentine derived HA from sheep teeth.
  • [36] Goller G, Oktar FN, Key Eng Mater 2002;206-212:1615-20.
  • [37] Oktar FN, "Microstructure and mechanical properties of sintered enamel hydroxyapatite", Ceram Int 2007;33:1309-14.
  • [38] Oktar FN, Goller G, "Sintering effects on mechanical properties of glass-reinforced hydroxyapatite composites", Ceram Int 2002;28:617-21.
  • [39] Goller G, Demirkıran H, Oktar FN, Demirkesen E, Ceram Int 2003;29:721-4.
  • [40] Goller G, Oktar FN, Toykan D, Kayali ES, Key Eng Mater 2003;240-242:619-22.
  • [41] Kurkcu M, Benlidayi ME, Ozsoy S, Ozyegin LS, Oktar FN, Kurtoglu C, J. Mater. Sci Mater Med 2008;19:59-65.
  • [42] Daglilar S, Erkan ME, Gunduz O, Ozyegin LS, Salman S, Agathopoulos S and et al., Mater. Lett. 2007;61:2295-98.
  • [43] Lemos AF, Rocha JHG, Quaresma SSF, Kannan S, Oktar FN, Agathopoulos S and et al., J Eur Ceram Soc 2006;26:3639-46.
  • [44] Tuyel U, Oner ET, Ozyegin S, Oktar FN, J Biotech 2007;131S:S65-S66.
  • [45] Rocha JHG, Lemos AF, Agathopoulos S, Valério P, Kannan S, Oktar FN and et al., Bone 2005;37:850-7.
  • [46] Karacayli U, Gunduz O, Salman S, Ozyegin LS, Agathopoulos S, Oktar FN, Effect of sintering temperature on mechanical properties and microstructure of sheep-bone derived hydroxyapatite (SHA). The 13th International Conference on Biomedical Engineering, Singapoure, 3-6 December 2008. Proceedings pp. 103-4.
  • [47] Gunduz O, Karacayli U, Salman S, Kayali ES, Sengil AZ, Agathopoulos S and et al., A Novel Natural Hydroxyapatite: Sheep Hydroxyapatite. 22nd International Symposium on Ceramics in Medicine “Bioceramics-22”, Daegu, Korea, 26-29 October, 2009. Proceedings pp. 483-6.
  • [48] Kannan S, Goetz-Neunhoeffer F, Neubauer J, Ferreira JMF, J Am Ceram Soc 2008; 91:1-12.
There are 60 citations in total.

Details

Primary Language Turkish
Subjects Engineering
Journal Section Research Articles
Authors

Mustafa Sengor 0000-0002-2447-7538

Publication Date January 30, 2021
Published in Issue Year 2021 Volume: 33 Issue: 1

Cite

APA Sengor, M. (2021). Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2. International Journal of Advances in Engineering and Pure Sciences, 33(1), 116-121. https://doi.org/10.7240/jeps.771433
AMA Sengor M. Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2. JEPS. January 2021;33(1):116-121. doi:10.7240/jeps.771433
Chicago Sengor, Mustafa. “Microstructure and Mechanical Properties of Composites of Bovine Derived Hydroxyapatite (BHA) Reinforced With MgF2”. International Journal of Advances in Engineering and Pure Sciences 33, no. 1 (January 2021): 116-21. https://doi.org/10.7240/jeps.771433.
EndNote Sengor M (January 1, 2021) Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2. International Journal of Advances in Engineering and Pure Sciences 33 1 116–121.
IEEE M. Sengor, “Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2”, JEPS, vol. 33, no. 1, pp. 116–121, 2021, doi: 10.7240/jeps.771433.
ISNAD Sengor, Mustafa. “Microstructure and Mechanical Properties of Composites of Bovine Derived Hydroxyapatite (BHA) Reinforced With MgF2”. International Journal of Advances in Engineering and Pure Sciences 33/1 (January 2021), 116-121. https://doi.org/10.7240/jeps.771433.
JAMA Sengor M. Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2. JEPS. 2021;33:116–121.
MLA Sengor, Mustafa. “Microstructure and Mechanical Properties of Composites of Bovine Derived Hydroxyapatite (BHA) Reinforced With MgF2”. International Journal of Advances in Engineering and Pure Sciences, vol. 33, no. 1, 2021, pp. 116-21, doi:10.7240/jeps.771433.
Vancouver Sengor M. Microstructure and mechanical properties of composites of bovine derived hydroxyapatite (BHA) reinforced with MgF2. JEPS. 2021;33(1):116-21.

Cited By

Effects of sintering and zirconmullite doping on nanostructural vacancies of bovine hydroxyapatite by positron techniques
Journal of the American Ceramic Society
https://doi.org/10.1111/jace.18985