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UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER

Year 2022, , 600 - 618, 29.05.2022
https://doi.org/10.33483/jfpau.1085681

Abstract

Amaç: Uyuz hastalığı (Skabiyes) dünyada yaygın olarak görülen kaşıntılı, döküntülü ve bulaşıcı ektoparaziter bir hastalıktır. Etken Sarcoptes scabiei var. hominis adı verilen mikroskobik bir eklem bacaklıdır. Her yaş, cinsiyet, coğrafya ve kültürden insanı etkileyebilir. Gelişmekte olan ülkeler, tropikal ve subtropikal ülkelerde endemik olan parazit nedenli bu hastalık, büyük kalabalıklar ve hijyenin korunamadığı ortamlarda salgınlar yapabilir. Tedavide topikal ve oral olarak kullanılan seçenekler kısıtlı sayıdadır. Permetrin, Benzil Benzoat, Kükürtlü merhemler, Lindan, İvermektin gibi ilaçların birçoğu toksik etkilerinden dolayı bebek, çocuk, gebe ve laktasyon ile ilgili kısıtlılıklar nedeniyle risk altındaki tüm popülasyonlara uygulanamamaktadır. Scabiyes tedavi edilmediğinde, özellikle pediyatrik yaş grubunda görülen piyoderma, impetigo gibi sekonder enfeksiyonların da tabloya eklenmesi, hastalığın yükünü artırmaktadır. Bu nedenle daha az toksik etkileri olan ilaç arayışları halihazırda kullanılagelen bitkilere olan ilgiyi de canlı tutmaktadır.
Sonuç ve Tartışma: Sporadik ya da epidemik tüm vakalarda, yayılımı önlemek için skabiyesin etkin tedavisi şarttır. Başarılı bir tedavi, ilaç uygulamasının doğru yapılmasına, tedavinin komplikasyonlar ve semptomları kontrol etmeye yönelik ek yaklaşımları içermesine ve beraberinde koruyucu önlemlerin alınmasına bağlıdır. Bu derlemede skabiyes, tedavisi, kullanılan ilaçlar, kullanılma potansiyeli olan yeni ilaçlar ve geleneksel olarak kullanılan bitkiler incelenmiştir. Ülkemizde yetişen, tanınan ve yetişme potansiyeli olan 49 taksonun uyuz hastalığı tedavisinde kullanıldığı belirlenmiştir. 

References

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SCABIES, SCABIES TREATMENT AND PLANTS USED IN THE TREATMENT OF SCABIES

Year 2022, , 600 - 618, 29.05.2022
https://doi.org/10.33483/jfpau.1085681

Abstract

Objective: Scabies are an itch and contagious ectoparasite that is common around the World. There is the causative Sarcoptes scabiei var. hominis. It can affect people of all ages, sexes, geographies and cultures. It is endemic in developing countries, tropical and subtropical countries. It can cause epidemics in large crowds and environments where hygiene cannot be maintained. Topical and oral options for treatment are limited. Drugs such as Permethrin, Benzyl Benzoate, Sulfur Ointments, Lindan, Ivermectin cannot be applied to all populations at risk due to their toxic effects, infants, children, pregnant women, and lactation-related restrictions. When scabies are not treated, the addition of secondary infections such as pyoderma and impetigo, which are seen especially in the pediatric age group, increases the burden of the disease. For that reason, the search for drugs with less toxic effects keeps the interest in plants still alive.
Result and Discussion: In all cases of sporadic or epidemic, effective treatment of scabies is essential to prevent to spread. Successful treatment depends on the correct administration of the medication, the inclusion of additional approaches to control complications and symptoms and the taking of preventive measures. In this review, scabies, their treatment, drugs used, new drugs with the potential to be used and traditionally used plants were examined. It has been determined that 49 taxa that are grown, known and have the potential to grow in our country are used in the treatment of scabies.

References

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  • 2. Thomas, C., Coates, S. J., Engelman, D., Chosidow, O. and Chang, A. Y. (2020). Ectoparasites: Scabies. J Am Acad Dermatol, 82 (3) 533-548. [CrossRef]
  • 3. Jackson, R. (2004). Scabies by Kenneth Mellanby. J Cutan Med Surg, 8 (2) 73-76. [CrossRef]
  • 4. Organization, W. H. Web cite (2020). From https://www.who.int/news-room/fact-sheets/detail/scabie Erişim Tarihi: 10.09.2020 5. Wang, C. H., Lee, S. C., Huang, S. S., Kao, Y. C., See, L. C. and Yang, S. H. (2012). Risk factors for scabies in Taiwan. J Microbiol Immunol Infect, 45 (4) 276-280. [CrossRef]
  • 6. Ciftci, I. H., Karaca, S., Dogru, O., Cetinkaya, Z. and Kulac, M. (2006). Prevalence of pediculosis and scabies in preschool nursery children of Afyon, Turkey. Korean J Parasitol, 44 (1) 95-98. [CrossRef]
  • 7. Çetinkaya, Ü., Şahin, S. and Ulutabanca, R. (2018). The Epidemiology of Scabies and Pediculosis in Kayseri. Turkiye Parazitol Derg, 42 (2) 134-137. [CrossRef]
  • 8. Thomas, J., Peterson, G. M., Walton, S. F., Carson, C. F., Naunton, M. and Baby, K. E. (2015). Scabies: an ancient global disease with a need for new therapies. BMC Infectious Diseases, 15 (1) 250. [CrossRef]
  • 9. GBD. (2017). Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 390 (10100) 1211-1259. [CrossRef]
  • 10. Cinotti, E., Perrot, J. L., Labeille, B., Maguet, H., Couzan, C., Flori, P. and Cambazard, F. (2015). Inefficacy of alcohol-based hand rub on mites in a patient with hyperkeratotic scabies. Clin Exp Dermatol, 40 (2) 177-181. [CrossRef]
  • 11. Hicks, M. I. and Elston, D. M. (2009). Scabies. Dermatol Ther, 22 (4) 279-292. [CrossRef]
  • 12. Kazan, D. and Demirsoy, E. O. SKABİYES; KLİNİK BULGULAR, TANI VE TEDAVİ. Acta Medica Nicomedia, 3 (2) 80-87,
  • 13. Şimşek, E., Keskin, A. and Dağcıoğlu, B. F. (2019). Sık Rastlanan ve Sık Atlanan Hastalık Uyuz: Olgu Sunumu. Ankara Medical Journal, 19 (1) 205-209. [CrossRef]
  • 14. Shimose, L. and Munoz-Price, L. S. (2013). Diagnosis, prevention, and treatment of scabies. Curr Infect Dis Rep, 15 (5) 426-431. [CrossRef]
  • 15. Tai, D. B. G., Abu Saleh, O. and Miest, R. (2020). Genital nodular scabies. IDCases, 22 e00947. [CrossRef]
  • 16. Çetin, B. Ş. (2017). Uyuz Hastalığına Yaklaşım (Güncel Kılavuz Değerlendirmesi). Cocuk Enfeksiyon Dergisi, 11 (2) 107-109. [CrossRef]
  • 17. Leung, A. K. C., Lam, J. M. and Leong, K. F. (2020). Scabies: A Neglected Global Disease. Curr Pediatr Rev, 16 (1) 33-42. [CrossRef]
  • 18. Micali, G., Lacarrubba, F., Verzì, A. E., Chosidow, O. and Schwartz, R. A. (2016). Scabies: Advances in Noninvasive Diagnosis. PLoS Negl Trop Dis, 10 (6) e0004691. [CrossRef]
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There are 71 citations in total.

Details

Primary Language Turkish
Subjects Pharmacology and Pharmaceutical Sciences
Journal Section Collection
Authors

Jale Akgöl 0000-0002-9163-3991

Ayşegül Köroğlu 0000-0002-8450-1376

Publication Date May 29, 2022
Submission Date March 10, 2022
Acceptance Date April 15, 2022
Published in Issue Year 2022

Cite

APA Akgöl, J., & Köroğlu, A. (2022). UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER. Journal of Faculty of Pharmacy of Ankara University, 46(2), 600-618. https://doi.org/10.33483/jfpau.1085681
AMA Akgöl J, Köroğlu A. UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER. Ankara Ecz. Fak. Derg. May 2022;46(2):600-618. doi:10.33483/jfpau.1085681
Chicago Akgöl, Jale, and Ayşegül Köroğlu. “UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER”. Journal of Faculty of Pharmacy of Ankara University 46, no. 2 (May 2022): 600-618. https://doi.org/10.33483/jfpau.1085681.
EndNote Akgöl J, Köroğlu A (May 1, 2022) UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER. Journal of Faculty of Pharmacy of Ankara University 46 2 600–618.
IEEE J. Akgöl and A. Köroğlu, “UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER”, Ankara Ecz. Fak. Derg., vol. 46, no. 2, pp. 600–618, 2022, doi: 10.33483/jfpau.1085681.
ISNAD Akgöl, Jale - Köroğlu, Ayşegül. “UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER”. Journal of Faculty of Pharmacy of Ankara University 46/2 (May 2022), 600-618. https://doi.org/10.33483/jfpau.1085681.
JAMA Akgöl J, Köroğlu A. UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER. Ankara Ecz. Fak. Derg. 2022;46:600–618.
MLA Akgöl, Jale and Ayşegül Köroğlu. “UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER”. Journal of Faculty of Pharmacy of Ankara University, vol. 46, no. 2, 2022, pp. 600-18, doi:10.33483/jfpau.1085681.
Vancouver Akgöl J, Köroğlu A. UYUZ HASTALIĞI (SKABİYES), TEDAVİSİ VE UYUZ HASTALIĞI TEDAVİSİNDE KULLANILAN BİTKİLER. Ankara Ecz. Fak. Derg. 2022;46(2):600-18.

Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.