ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM.

Burçin Ergene; Özlem Bahadır Acıkara; Filiz Bakar; Gülçin Saltan; Serpil Nebioğlu

doi:10.1501/Eczfak_0000000560

ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM.

Year 2010, Volume: 39 Issue: 2, 145 - 154, 01.06.2010

Burçin Ergene Özlem Bahadır Acıkara Filiz Bakar Gülçin Saltan Serpil Nebioğlu

https://doi.org/10.1501/Eczfak_0000000560

Cited By: 10

https://izlik.org/JA28GC77DU

Abstract

In present study, the extracts prepared using aerial parts and roots of Alchemilla persica Rothm. were evaluated for their antioxidant activity by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay and measurement of malondialdehyde (MDA) levels. HPLC analyses of the extracts were also performed using some phenolic acid and flavonoid standards. The hydro-methanolic extract of the aerial parts was found to possess significant antioxidant activity in both assays. IC50 values for the aerial parts and roots are determined as 0.055 M and 0.151 M respectively against DPPH radical. In TBARS assay, the MDA level of the aerial parts was found to be 5.9 nmol/ml, while 19.08 nmol/ml for the root extracts

Keywords

Alchemilla persica , Rosaceae , Antioxidant activity , DPPH , MDA

ALCHEMILLA PERSICA ROTHM. BĐTKĐSĐNĐN ANTĐOKSĐDAN AKTĐVĐTESĐ VE FĐTOKĐMYASAL ANALĐZĐ

Year 2010, Volume: 39 Issue: 2, 145 - 154, 01.06.2010

Burçin Ergene Özlem Bahadır Acıkara Filiz Bakar Gülçin Saltan Serpil Nebioğlu

https://doi.org/10.1501/Eczfak_0000000560

Cited By: 10

https://izlik.org/JA28GC77DU

Abstract

Bu çalışmada Alchemilla persica Rothm.’nın (Rosaceae) toprak üstü ve köklerinden hazırlanan ekstrelerin antioksidan aktivitesi 1,1-difenil-2-pikrilhidrazil (DPPH) radikal süpürücü etki ve malondialdehit (MDA) seviyelerinin ölçülmesiyle tespit edilmiştir. Bazı fenolik asit ve flavonoit standartları kullanılarak ekstrelerin YBSK analizleri de gerçekleştirilmiştir. Toprak üstü kısımlarından hazırlanan ekstre belirgin bir antioksidan aktivite göstermiştir. DPPH radikaline karşı toprak üstü ve kök ekstreleri için IC50 değeri sırasıyla 0.055 M ve 0.151 M olarak belirlenmiştir. Tespit edilen MDA seviyesi toprak üstü ekstresi için 5.9 nmol/ml, iken kök ekstresi için 19.08 nmol/ml’dir

Keywords

Alchemilla persica , Rosaceae , Antioxidant activity , DPPH , MDA

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Details

Other ID	JA55ZP64PB
Authors	Burçin Ergene This is me Özlem Bahadır Acıkara This is me Filiz Bakar This is me Gülçin Saltan This is me Serpil Nebioğlu This is me
Submission Date	June 1, 2010
Publication Date	June 1, 2010
DOI	https://doi.org/10.1501/Eczfak_0000000560
IZ	https://izlik.org/JA28GC77DU
Published in Issue	Year 2010 Volume: 39 Issue: 2

Cite

APA	Ergene, B., Bahadır Acıkara, Ö., Bakar, F., Saltan, G., & Nebioğlu, S. (2010). ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Journal of Faculty of Pharmacy of Ankara University, 39(2), 145-154. https://doi.org/10.1501/Eczfak_0000000560
AMA	1.Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. J. Fac. Pharm. Ankara. 2010;39(2):145-154. doi:10.1501/Eczfak_0000000560
Chicago	Ergene, Burçin, Özlem Bahadır Acıkara, Filiz Bakar, Gülçin Saltan, and Serpil Nebioğlu. 2010. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University 39 (2): 145-54. https://doi.org/10.1501/Eczfak_0000000560.
EndNote	Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S (June 1, 2010) ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Journal of Faculty of Pharmacy of Ankara University 39 2 145–154.
IEEE	[1]B. Ergene, Ö. Bahadır Acıkara, F. Bakar, G. Saltan, and S. Nebioğlu, “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”., J. Fac. Pharm. Ankara, vol. 39, no. 2, pp. 145–154, June 2010, doi: 10.1501/Eczfak_0000000560.
ISNAD	Ergene, Burçin - Bahadır Acıkara, Özlem - Bakar, Filiz - Saltan, Gülçin - Nebioğlu, Serpil. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University 39/2 (June 1, 2010): 145-154. https://doi.org/10.1501/Eczfak_0000000560.
JAMA	1.Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. J. Fac. Pharm. Ankara. 2010;39:145–154.
MLA	Ergene, Burçin, et al. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University, vol. 39, no. 2, June 2010, pp. 145-54, doi:10.1501/Eczfak_0000000560.
Vancouver	1.Burçin Ergene, Özlem Bahadır Acıkara, Filiz Bakar, Gülçin Saltan, Serpil Nebioğlu. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. J. Fac. Pharm. Ankara. 2010 Jun. 1;39(2):145-54. doi:10.1501/Eczfak_0000000560

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The Journal of Faculty of Pharmacy of Ankara University is an international medium, an open access, peer-reviewed journal for the publication of original research reports, reviews and short communications in English or Turkish on relevant developments in pharmaceutical sciences., Proceeding of scientific meetings may be published as special issues of supplements to the journal. Additionally, it contains previous and forthcoming national and international scientific meetings with social activities in pharmaceutical areas.