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ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM.

Year 2010, , 145 - 154, 01.06.2010

Burçin Ergene Özlem Bahadır Acıkara Filiz Bakar Gülçin Saltan Serpil Nebioğlu

https://doi.org/10.1501/Eczfak_0000000560
Cited By: 7

Abstract

In present study, the extracts prepared using aerial parts and roots of Alchemilla persica Rothm. were evaluated for their antioxidant activity by using 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay and measurement of malondialdehyde (MDA) levels. HPLC analyses of the extracts were also performed using some phenolic acid and flavonoid standards. The hydro-methanolic extract of the aerial parts was found to possess significant antioxidant activity in both assays. IC50 values for the aerial parts and roots are determined as 0.055 M and 0.151 M respectively against DPPH radical. In TBARS assay, the MDA level of the aerial parts was found to be 5.9 nmol/ml, while 19.08 nmol/ml for the root extracts

Keywords

Alchemilla persica Rosaceae Antioxidant activity DPPH MDA

ALCHEMILLA PERSICA ROTHM. BĐTKĐSĐNĐN ANTĐOKSĐDAN AKTĐVĐTESĐ VE FĐTOKĐMYASAL ANALĐZĐ

Year 2010, , 145 - 154, 01.06.2010

Burçin Ergene Özlem Bahadır Acıkara Filiz Bakar Gülçin Saltan Serpil Nebioğlu

https://doi.org/10.1501/Eczfak_0000000560
Cited By: 7

Abstract

Bu çalışmada Alchemilla persica Rothm.’nın (Rosaceae) toprak üstü ve köklerinden hazırlanan ekstrelerin antioksidan aktivitesi 1,1-difenil-2-pikrilhidrazil (DPPH) radikal süpürücü etki ve malondialdehit (MDA) seviyelerinin ölçülmesiyle tespit edilmiştir. Bazı fenolik asit ve flavonoit standartları kullanılarak ekstrelerin YBSK analizleri de gerçekleştirilmiştir. Toprak üstü kısımlarından hazırlanan ekstre belirgin bir antioksidan aktivite göstermiştir. DPPH radikaline karşı toprak üstü ve kök ekstreleri için IC50 değeri sırasıyla 0.055 M ve 0.151 M olarak belirlenmiştir. Tespit edilen MDA seviyesi toprak üstü ekstresi için 5.9 nmol/ml, iken kök ekstresi için 19.08 nmol/ml’dir

Keywords

Alchemilla persica Rosaceae Antioxidant activity DPPH MDA

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Details

Other ID JA55ZP64PB
Journal Section Research Article
Authors

Burçin Ergene This is me

Özlem Bahadır Acıkara This is me

Filiz Bakar This is me

Gülçin Saltan This is me

Serpil Nebioğlu This is me

Publication Date June 1, 2010
Submission Date June 1, 2010
Published in Issue Year 2010

Cite

APA Ergene, B., Bahadır Acıkara, Ö., Bakar, F., Saltan, G., et al. (2010). ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Journal of Faculty of Pharmacy of Ankara University, 39(2), 145-154. https://doi.org/10.1501/Eczfak_0000000560
AMA Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Ankara Ecz. Fak. Derg. June 2010;39(2):145-154. doi:10.1501/Eczfak_0000000560
Chicago Ergene, Burçin, Özlem Bahadır Acıkara, Filiz Bakar, Gülçin Saltan, and Serpil Nebioğlu. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University 39, no. 2 (June 2010): 145-54. https://doi.org/10.1501/Eczfak_0000000560.
EndNote Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S (June 1, 2010) ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Journal of Faculty of Pharmacy of Ankara University 39 2 145–154.
IEEE B. Ergene, Ö. Bahadır Acıkara, F. Bakar, G. Saltan, and S. Nebioğlu, “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”., Ankara Ecz. Fak. Derg., vol. 39, no. 2, pp. 145–154, 2010, doi: 10.1501/Eczfak_0000000560.
ISNAD Ergene, Burçin et al. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University 39/2 (June 2010), 145-154. https://doi.org/10.1501/Eczfak_0000000560.
JAMA Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Ankara Ecz. Fak. Derg. 2010;39:145–154.
MLA Ergene, Burçin et al. “ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM”. Journal of Faculty of Pharmacy of Ankara University, vol. 39, no. 2, 2010, pp. 145-54, doi:10.1501/Eczfak_0000000560.
Vancouver Ergene B, Bahadır Acıkara Ö, Bakar F, Saltan G, Nebioğlu S. ANTIOXIDANT ACTIVITY AND PHYTOCHEMICAL ANALYSIS OF ALCHEMILLA PERSICA ROTHM. Ankara Ecz. Fak. Derg. 2010;39(2):145-54.

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Kapsam ve Amaç

Ankara Üniversitesi Eczacılık Fakültesi Dergisi, açık erişim, hakemli bir dergi olup Türkçe veya İngilizce olarak farmasötik bilimler alanındaki önemli gelişmeleri içeren orijinal araştırmalar, derlemeler ve kısa bildiriler için uluslararası bir yayım ortamıdır. Bilimsel toplantılarda sunulan bildiriler supleman özel sayısı olarak dergide yayımlanabilir. Ayrıca, tüm farmasötik alandaki gelecek ve önceki ulusal ve uluslararası bilimsel toplantılar ile sosyal aktiviteleri içerir.