SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE

Oya Bozdağ Dündar

doi:10.1501/Eczfak_0000000067

TR EN

ETİL {5-[(2-(4-KLOROBENZİLSULFANİL)-4-KLOROTİYAZOL-5- İL)METİLEN]-2,4-DİOKSO-TİYAZOLİDİN–3-İL} ASETAT BİLEŞİĞİNİN SENTEZİ VE ALDOZ REDÜKTAZ İNHİBİTÖR ETKİSİ : SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY

Abstract

Bu çalışmada, etil {5-[(2-(4-klorobenzilsulfanil)-4-klorotiyazol-5-il)metilen]-2,4-dioksotiyazolidin–3-il}asetat bileşiği sentez edilmiş ve yapısı IR, 1H-NMR, mass and elementel analiz bulguları ile aydınlatılmıştır. Sentez edilen bileşiğin, in-vitro ortamda spektrofotometrik olarak sıçan böbrek AR’ını inhibe etme gücü test edilmiştir. Sentez edilen bileşik % 6.51±0.97 inhibitor aktivite göstermiştir

Keywords

Tiyazolidin-2,4-dionlar, tiyazol türevleri, aldoz redüktaz inhibitör etki

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Oya Bozdağ Dündar This is me

Publication Date

December 1, 2006

Submission Date

December 1, 2006

Acceptance Date

-

Published in Issue

Year 2006 Volume: 35 Number: 4

DOI

https://doi.org/10.1501/Eczfak_0000000067

IZ

https://izlik.org/JA82YS39KS

Cite

RIS / Bibtex

APA

Bozdağ Dündar, O. (2006). SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE. Journal of Faculty of Pharmacy of Ankara University, 35(4), 245-254. https://doi.org/10.1501/Eczfak_0000000067

AMA

1.Bozdağ Dündar O. SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE. J. Fac. Pharm. Ankara. 2006;35(4):245-254. doi:10.1501/Eczfak_0000000067

Chicago

Bozdağ Dündar, Oya. 2006. “SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE”. Journal of Faculty of Pharmacy of Ankara University 35 (4): 245-54. https://doi.org/10.1501/Eczfak_0000000067.

EndNote

Bozdağ Dündar O (December 1, 2006) SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE. Journal of Faculty of Pharmacy of Ankara University 35 4 245–254.

IEEE

[1]O. Bozdağ Dündar, “SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE”, J. Fac. Pharm. Ankara, vol. 35, no. 4, pp. 245–254, Dec. 2006, doi: 10.1501/Eczfak_0000000067.

ISNAD

Bozdağ Dündar, Oya. “SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE”. Journal of Faculty of Pharmacy of Ankara University 35/4 (December 1, 2006): 245-254. https://doi.org/10.1501/Eczfak_0000000067.

JAMA

1.Bozdağ Dündar O. SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE. J. Fac. Pharm. Ankara. 2006;35:245–254.

MLA

Bozdağ Dündar, Oya. “SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE”. Journal of Faculty of Pharmacy of Ankara University, vol. 35, no. 4, Dec. 2006, pp. 245-54, doi:10.1501/Eczfak_0000000067.

Vancouver

1.Oya Bozdağ Dündar. SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY EFFECT OF ETHYL {5-[(2- (4-CHLORO-BENZYLSULPHANYL)- 4-CHLORO-THİAZOLE-5-YL)METHYLENE]- 2,4-DIOXO-THİAZOLİDİNE–3-YL}ACETATE. J. Fac. Pharm. Ankara. 2006 Dec. 1;35(4):245-54. doi:10.1501/Eczfak_0000000067

ETİL {5-[(2-(4-KLOROBENZİLSULFANİL)-4-KLOROTİYAZOL-5- İL)METİLEN]-2,4-DİOKSO-TİYAZOLİDİN–3-İL} ASETAT BİLEŞİĞİNİN SENTEZİ VE ALDOZ REDÜKTAZ İNHİBİTÖR ETKİSİ : SYNTHESIS AND ALDOSE REDUCTASE INHIBITORY

Abstract

Keywords