SYNTHESIS OF SOME NEW MANNICH BASES OF 6-ACYL-5-CHLORO-2-BENZOXAZOLINONES : BAZI YENİ MANNICH BAZI 6-AÇİL-5-KLORO-2-BENZOKSAZOLINONLARIN SENTEZLERİ

Abstract

Bu çalışmada, 3 numaralı konumda piperazinometil (veya piperidinometil) grubu taşıyan 6-açil- 5-chloro-2-benzoksazolinon türevi yedi tane yeni bileşik, uygun benzoksazolinonlar ve 4-substitue piperazin (veya 4-substitue piperidin) kullanılarak Mannich reaksiyonuyla sentezlenmiştir. Bileşiklerin kimyasal yapıları IR, 'H-NMR ve elemental analizleriyle kanıtlanmıştır.

Keywords

• 2-Benzoksazolinon, sentez, acilleme, mannich bazları

SYNTHESIS OF SOME NEW MANNICH BASES OF 6-ACYL-5-CHLORO-2-BENZOXAZOLINONES

Abstract

n this study, seven new 6-acyl-5-chloro-2-benzoxazolinone derivatives having a piperazinomethyl (or piperidinomethyl) group at the third position of the ring were synthesized by using appropriate benzoxazolinones and 4-substituted piperazines (or 4-substituted piperidines) via a Mannich reaction. The chemical structures of the compounds were elucidated by IR, 'H-NMR and elemental analysis.

Keywords

• 2-Benzoxazolinones, synthesis, acylation, mannich bases